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MTAP 1 Bacte > (Part 2) 2.22.3 Clostridium > Flashcards

(Part 2) 2.22.3 Clostridium Flashcards

1
Q

Clostridium Endospores are for aerobically

T or F

A

F

Anaerobically

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2
Q

Clostridium is Gram?

A

Pos

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3
Q

Clostridium is a normal flora

T or F

A

T

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4
Q

Produces an extremely potent neurotoxin (BoNT)

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

b

[Botulinum neurotoxin]

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5
Q

Produces up to sevn exotoxins, including lethal toxin (LT), Hemorrhagic Toxin (HT) and enterotoxin A, B, C

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

c

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6
Q

Produces toxin A (TcdA) which is an enterotoxin, and toxin B (TcdB) which is a cytotoxic

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

e

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7
Q

Produces several exotoxins:

alphatoxin - destroys host cell membrane

Enterotoxin - insert and disrupts membrane

Beta toxin - cytotoxin

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

d

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8
Q

Produces a GTP (Glycosylate guanosine triphosphate which signals proteins to breakdown cellular cytotoxin and cell death

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

e

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9
Q

Produces tetanospasmin (TeNT), a neurotoxic exotoxin that disrupts nerve impulses to muscles

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

a

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10
Q

Causes tetanus

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

a

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11
Q

Commonly known as lockjaw

A

Tetanus

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12
Q

Causes foodborne botulism, Infant botulism, wound botulism, and intestinal botulism

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

b

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13
Q

Foodborne botulism colonizes GI tract of infants

T or F

A

F

Foodborne botulism is a flaccid paralysis (Rag doll)

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14
Q

Type of botulism associated with surgery and antibiotics

A

Intestinal botulism

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15
Q

Causes gas gangrene, necrotizing fasciitis, food poisoning, and enteritis necroticans

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

d

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16
Q

Causes Gas gangrene of the uterus as a result of abortion, normal , delivery, or cesarean section

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

c

17
Q

This organism requires diminution of normal gut microbiota by the activity of various antimicrobial agents

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

e

18
Q

Causes antibiotic-associated diarrhea and Pseudomembranous colitis

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

e

19
Q

The only terminally located endospore in clostridium

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

a

20
Q

Clostridium tetani is also known as?

A

Drumstick/Tackhead bacillus

Terminally = Endospore are at the end of bacillus

21
Q

Clostridium perfringens endospores are rarely observed

T or F

A

T

22
Q

What is the modified version of Lecithinase test

A. Neufeld Reaction
B. Nagler Reaction
c. Niger Reaction
d. Neufold Reaction

A

b

23
Q

Causes the double zone of inhibition

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

d

24
Q

Inner zone = Beta lysis (Theta toxin)

Outer zone = Alpha toxin

T or F

A

T

25
Q

In reverse CAMP test, what is the streak organism/Control organism

a. S. agalactiae
b. Staph. aureus
c. Clostridium perfringens
d. Listeria monocytogenes

A

a

26
Q

Positive in Reverse CAMP?

a. C. tetani
b. C. botulinum
c. C. sordelii
d. C. perfringens
e. C. difficile

A

d

27
Q

Positive indicator for Lipase test?

A

Iredescent sheen when held at an angle to a light source

28
Q

CCFA Medium (Cycloserin-Cefoxitin Fructose agar

Cycloserine- inhibits G(-)
Cefoxitin - inhibits G (+) and (-) but C. difficile

T or F

A

T

29
Q

in CCFA, Colonies of C. difficile is describe?

A

Yellow ground glass

MTAP 1 Bacte (93 decks)

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