(Part 2) 2.23.1 Mycobacterium Flashcards

1
Q

Atm req for Mycobacterium?

A

O. aerobic

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2
Q

Mycobacterium, motile

T or F

A

F

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3
Q

Mycobacterium is Gram positive

T or F

A

T

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4
Q

Spp. of Mycobacterium that caust the most cases of human tuberculosis

A

M. tuberculosis

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5
Q

Primary reservoir for tuberculosis?

a. Cavitary disease
b. Pulmonary disease
c. Kidney disease
d. GI disease

A

a

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6
Q

MOT of M. tuberculosis

A

Inhalation of droplet nuclei

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7
Q

Skin test to identify individuals infected with M. tuberculosis

a. PPD
b. T-spot TB test
c. Quantiferon-TB gold

A

PPD (Purified protein derivative)

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8
Q

In PPD, After 48-72 hours, infected individuals show erythema and
induration (+)

T or F

A

T

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9
Q

In PPD (+) is <10

t or F

A

F

> 10

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10
Q

An assay which measures T cell that have been activated by M. tuberculosis antigens

a. PPD
b. T-spot TB test
c. Quantiferon-TB gold

A

b

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11
Q

Based on the quantification of Interferon-Gamma released from sensitized lymphocytes in heparinized whole blood that has been incubated overnight

a. PPD
b. T-spot TB test
c. Quantiferon-TB gold

A

c

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12
Q

Sample used in Quantiferon-TB Gold

a. Serum
b. Whole blood without Plasma
c. Heparinized whole Blood
d. Coagulated Whole Blood

A

c

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13
Q

in Nontuberculous Mycobacteria (NTM) , membaers are opportunistic pathogens and not usually transmitted from person to person

T or F

A

T

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14
Q

Slow growing NTM, pigmented colonies in both light and Dark

a. Photochromogens
b. Scotochromogens
c. Non-Photochromogens
d. Rapid growers

A

b

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15
Q

Slow growing NTM, pigmented colonies only in light

a. Photochromogens
b. Scotochromogens
c. Non-Photochromogens
d. Rapid growers

A

a

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16
Q

Slow growing NTM, Non-pigmented colonies in regardless if light or Dark

a. Photochromogens
b. Scotochromogens
c. Non-Photochromogens
d. Rapid growers

A

c

17
Q

NTM colonies grow in less than 7 days or earlier

a. Photochromogens
b. Scotochromogens
c. Non-Photochromogens
d. Rapid growers

A

d

18
Q

M. kansasii
M. asiaticum
M. marinum
M. intermedium
M. branderi

(KAMIB, Only “K”, “M”, “B” in the NTM spp. and in this Categories)

a. Photochromogens
b. Scotochromogens
c. Non-Photochromogens
d. Rapid growers

A

a

may spp sa ibang categories na nag sisimula sa “A” and “I”

19
Q

Mycobacterium terrae complex
Mycobacterium avium complex
M. gastri

(TAG, Only “T” is unique in this category)

a. Photochromogens
b. Scotochromogens
c. Non-Photochromogens
d. Rapid growers

A

c

20
Q

M. szulgai
M. scrofulaceum
M. gordonae
M. europeaeum
M. interjectum

(GoSS In Europe, Only “S” and “E” are unique in this categry)

a. Photochromogens
b. Scotochromogens
c. Non-Photochromogens
d. Rapid growers

A

b

21
Q

M. abscessus subsp. abscessus
M. chelonae,
M. fortuitum

(FAC, Only “F” and “C” is unique)

a. Photochromogens
b. Scotochromogens
c. Non-Photochromogens
d. Rapid growers

A

d

22
Q

The only Mycobacterium that is noncultivable

a. M. tuberculosis
b. M. kansasii
c. M. leprae
d. M. terrae complex

A

c

23
Q

Mycobacterium Leprae causes?

a. Hansen disease
b. Gas gangrene
c. Manuel disease
d. Ginger disease

A

a

24
Q

MOT of M. leprae

A

Inhalation of nasal secretions

25
Q

M. leprae cannot be cultivated in vitro

T or F

A

T

26
Q

M. leprae can be cultivated in the armadillo and footpads of mice

T or F

A

T

27
Q

PCR assays have been used to detect and identify M. leprae in infected tissues

T or F

A

T

28
Q

Most specimen for Mycobacterium are respiratory samples

T or F

A

T

29
Q

Sputum collection guidelines recommend collection of ______ specimens at least _______ apart

A

three, 8 hours

30
Q

Decontamination is necessary for non-sterile specimens to kill bacterial contaminants, Example of Decontaminant?

a. Ethanol
b. Sodium chloride
c. Ethyl acid
d. Sodium hydroxide

A

d

31
Q

Digestion is necessary for sputum which involves splitting the disulfide bonds that may trap mycobacteria, example of digesting agent?

a. EDTA
b. NALC
c. YMMS
d. PMRA

A

b. NALC (N-acetyl-L-cysteine)

32
Q

After digestion and decontamination, specimens are concentrated by centrifugation at _______

a. 2000 x g
b. 1000 x g
c. 4000 x g
d. 3000 x g

A

d