CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR (CRYOPRECIPITATE) Flashcards

1
Q

Shelflife, Thawed, and Pooled of CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR

A

> Frozen – 1 year
Thawed – 6 hours
Pooled – 4 hours

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2
Q

What is cryoprecipitate?

A

> Cryoprecipitate is a preparation rich in clotting factors of fibrin glue

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3
Q

How many Celcius in the storage temp for CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR (CRYOPRECIPITATE)

A

> Frozen= -18ºC or colder
Thawed – 20-24ºC

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4
Q

Give the contents about CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR (CRYOPRECIPITATE)

A

> Factor VIII:C - 80-150 IU
Factor VIII:vWF : 40 – 70 %
Fibrinogen – 150-250mg
Factor XIII : 20 – 30 %

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5
Q

Give the Indications about CRYOPRECIPITATED ANTIHEMOPHILIC FACTOR (CRYOPRECIPITATE)

A

> Hemophilia A, von Willebrand’sdse, Fibrinogen deficiency, Factor XIII deficiency

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6
Q

What is the purpose of Fibrin Glue when used in surgery with thrombin reagent?

A
  • Fibrin Glue, composed of an equal mixture of cryoprecipitate and thrombin reagent, serves as a topical application in surgical procedures.
  • Its primary function is to effectively halt hemorrhagic bleeding at the surgical site.
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7
Q

What coagulation factors are present in cryoprecipitate?

A
  • Factor 1 (Fibrinogen) and Factor 13.
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