1.4 Competitive + non-competitive inhibition Flashcards
1
Q
define an inhibitor
A
an substance or molecule which slows down the rate of enzyme controlled reaction
2
Q
what are the 2 types of inhibitors
A
- competitive
- non-competitive
3
Q
how do competitive inhibitors bind
A
- to the active site
- structurally SIMILAR
prevents enzyme/substrate complexes from forming
4
Q
does a competitive inhibitor compete for active site?
A
no, it collides with enzyme
5
Q
how do non competitive inhibitors bind
A
- binds to allosteric site, altering shape of active site (no longer complimentary), ∴ substrate molecule can longer fit
6
Q
what happens if you increase the substrate conc (non-competitive)
A
- will not increase rate
7
Q
what happens if you increase the substrate conc (competitive)
A
- increase rate
8
Q
A
