Ossficiation Flashcards
Where is the primary centre of ossification
Shaft of the bone
Where are the secondary centres of ossification
Epiphysis
How does primary ossification work?
Hyaline cartilage is where a future bone will be
Perichondrium of bone will begin to form osteoblasts, making bone collar
Chondrocytes begin to enlarge, everything around them begins to calcify
Chondrocyres die and leaves behind cavity which gets so large, it brings blood vessels and stem cells
Osteoblasts deposit bone matrix
Osteoclasts reabsorb bone matrix, making hollow cavity
Where does enchondral ossification take place?
- Physis (growth plate)
- Artocular wpiphysed cartilage complex
- Cuboidal bones
What stimulates cell division in the epiphyseal cartilage
IGF 1
What are cartilage canals
Channels within the cartilage, containing an arteriole, venules and capillaries
Provides blood to growth cartilage
What happens to cartilage canals
Under chondrigfication
Canal disappears
What is osteochondris
When cartilage isn’t replaced by bone
Focal failures
Why does osteochondrisis happen
Failure of blood vessels in cartilage canal, causing chondronecrosis at junction between cartilage and bone (lower layers where bone needs to replace cartilage). Necrotic regions don’t ossify
What is osteochondritis
Extension of lesions to the article surface, causes inflammation of the join g
What is osteochondritis disease
Presence of a osteochondral flap or loose fragment in the joint
What are the most common sides to see osteochondritis in horse?
Tibiotarswk joint
Femoropatellar
Fetlock joint
What are the most common osteochondrosis sites in a dog/
Shoulder
Stifle
Elbow
How is compression linked to growth rate
More compression —> higher growth rate
Excessive compression —> lower growth rate
What is physical dysplasia and what causes it
Enlargement of growth plate and metaphysis
Due to dismatch between metaphysical bone strength and applied loads
