14B Assignment Flashcards
If a mitochondrion wears out and can no longer maintain a proton gradient, it will also stop:
Fusion
Fission
Fusion
For electron carriers that are essential for many redox reactions in mitochondrial metabolism, what metal ion is necessary to support proper function of these electron carriers?
calcium
iron
potassium
magnesium
iron
Does succinate dehydrogenase, a component of the citric acid cycle, transfer electrons to the electron transport chain via action of NADH dehydrogenase (a.k.a. respiratory complex I)?
no
yes
no
Generally, for generation of the proton gradient across the inner mitochondrial membrane that is responsible for proton motive force is dependent on movement of protons from the _________ to the _______.
matrix; intermembrane space
intermembrane space; matrix
matrix; intermembrane space
When cytochrome c oxidase catalyzes the production of two water molecules, that requires incorporation of _______ into the water produced.
two protons and two electrons
four protons and four electrons
four protons and four electrons
Given the site of oxidation of NADH by NADH dehydrogenase, where is cytochrome c located?
cristae spaces
matrix
cytosol
cristae spaces
Which would be likely to interact with hydronium (H3O+)?
See figure legend for details of the other choice. Here, yes, partial negative charges on the hdroxyl groups of serine or threonine side chains
See figure legend for details of the other choice. Here, yes, negatively charged side chains of glutamate or aspartate
both
both
In a model of proton pumping by NADH dehydrogenase and cytochrome c oxidase. The proton is shown binding to the high-affinity state of the protein from the ________.
matrix side
cristae space
matrix side
The cristae spaces are parts of the ______ formed by the folding of the inner membrane.
intermembrane space
cytosol
matrix
intermembrane space
The NADH dehydrogenase pumps up to four H+ per electron, the cytochrome c reductase complex pumps two, whereas the cytochrome c oxidase complex pumps one per electron. So, how many protons are pumped after delivery of two electrons from NADH via NADH dehydrogenase.
seven
14
14 or fewer
seven or fewer
14 or fewer
The NADH dehydrogenase pumps up to four H+ per electron, the cytochrome c reductase complex pumps two, whereas the cytochrome c oxidase complex pumps one per electron. How many protons are pumped for two electrons from activity of succinate dehydrogenase, entering at ubiquinone and bypassing NADH dehydrogenase?
three
six
seven
14
six
