endocrine pathways

Question 1

thyroid hormone secretion

Answer 1

hypothalamus, TRH, anterior pituitary, TSH, thyroid gland, TH, target cells, circulation, BMR & body temp effects

Question 2

growth hormone secretion

Answer 2

hypothalamus, GnRH / GHIH -> anterior pit -> GH -> adipose, muscle, iver -> IGF-1

Question 3

stress comand pathway

Answer 3

stress -> hypothalamus -> CRH -> ant pit -> ATCH -> adrenal cortex -> cortisol -> most cells -> metabolic changes

Question 4

calcitonin/PTH pathway

Answer 4

low plasma Ca -> PTH -> increase PTH -> increase plasma Ca

high plasma Ca -> thyroid cells -> increase calcitonin -> decrease plasma Ca

Question 5

osteoblast pathway

Answer 5

osteoblasts -> RANK ligand or OPG

RANK ligand -> macrophages -> increase osteoclast action -> decrease bone mass

OPG -> rank ligand bound to OPG -> blocks RANK action -> decreased osteoclast action -> increased bone mass