002 Aliphatic Alkaloids

Question 1

amino acid intermediate of aliphatic alkaloids and determine which is essential and non-essential

Answer 1

lysine (essential)
ornithine (non-essential)

Question 2

lysine and ornithine is from what intermediate from the TCA cycle

Answer 2

oxaloacetate
a-ketoglutarate

Question 3

(3) reactions that form the aliphatic alkaloids in order

Answer 3

transamination
racemisation
decarboxylation

Question 4

examples of aliphatic alkaloids from ornithine and their distinguishing keywords

Answer 4

Pyrrolidine - 1 N and 4 C
Hygrine - coca leaves, cocaine, anticonvulsant

Question 5

examples of aliphatic alkaloids from lysine

Answer 5

Quinolizidine
Lupinine
Piperidine

Question 6

The word “alkaloid” was coined by ___________________ and derived from the Arabic word “al qali”, the plant from which soda was first isolated

Answer 6

Carl Friedrich Wilhelm Meissner