2-18-17 Flashcards

(43 cards)

1
Q

it’s not birth, marriage, or death, but _______ which is truly the most important moment of your life

A

gastrulation

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2
Q

skin and nervous - formed during gastrulation

A

ectoderm

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3
Q

respiratory and digestive - formed in gastrulation

A

endoderm

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4
Q

connective tisseu, blood, heart - formed during gastrulation

A

mesoderm

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5
Q

week one embryonic development events

A

fertilization, morula, blastocycst, implantation

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6
Q

polyspermy-

A

multiple sperm

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7
Q

zona pellucida

A

translucent layer around Oocyte, sperm attachment site, protects zygote, implantation to the uterus

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8
Q

Oocyte

A

egg+sperm??

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9
Q

acrosomal vesicle was originally derived from______

A

golgi

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10
Q

how does one sperm recognize an Oocyte

A

specific receptor on head of sperm that recognize zona pellicula

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11
Q

how is polyspermy prevented

A

binding increases opening of sodium channels and release of cortical granules

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12
Q

activation of sperm

A

exocytosis of the acrosomal vesicle (containing proteases)

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13
Q

4 key steps of fertilization

A
  1. binding of sperm 2. acrosomal reaction 3. penetration through zona pellucida 4. fusion of plasma membranes 5 sperm nucleaus enters egg cytoplasm.
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14
Q

cleavage begins about ______ hours post fertilization

A

30

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15
Q

blastomeres are ________

A

totipotent

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16
Q

cleavage leads to _______of the ________

A

compaction , morula

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17
Q

the morula is tightly adhered within the ________ __________

A

zona pellucida

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18
Q

blastomere is _____ the blastula

19
Q

how many cells in a blastomere?

20
Q

totipotency synonym

21
Q

the first cell differentiation event takes place in the __________

22
Q

parts of a blastocyst

A

blastocoel, zona pellucida, inner cell mass, trophoblast

23
Q

what portion of the blastocyst forms the embryo?

A

the inner cell mass

24
Q

Oct4 protein is expressed in the _______ cells of the __________

A

pluripotent ICM

25
totipotent
can give rise to any other cell in the body
26
pluripotent
can give rise to more than one other cell in the body
27
you can make a cell pluripotent by the introduction of _____ _________
transcription factors
28
we all _____ as embryos
hatch
29
we hatch from the _____ ______
zona pellucida
30
the chorion enables_______
the fetus to get oxegen and nutrients from the mother
31
syntrhophoblast
multiple nuclei and ……
32
3 types of monozygotic twins
unique chorion, shared chorion- ok, shared chorion-possible conjoined
33
cyncytiotrophoblast
intermediary trophoblast with finger like projections
34
ICM's form originally into a _____ _______
bilaminar disc
35
epiblast
part of the bilaminar disc
36
hypoblast cells
part of the bilaminar disc
37
connecting stalk connects to the _______
umbilical cord
38
the hypoblast is pushed away to form the ______
endoderm
39
top down order of first layers
ecto, meso, endoderm
40
almost 2/3 of fertilized embyos ______
terminate
41
how do you go from a sheet of cells into something as complex as a brain?
shaping, folding, closure
42
MHP
medial hinge points
43
folic acid supplements can prevent what?
50% of neural closure defects