Wk 6 Deck 1 Flashcards

1
Q

dorsal

A

back

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2
Q

anterior

A

head

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3
Q

posterior

A

tail

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4
Q

ventral

A

belly

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5
Q

when are the axes setup in development?

A

very early

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6
Q

what gene specifies eye development for humans and flies

A

Pax6

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7
Q

in humans and insects, does the same gene specify the formation of an eye?

A

yes, Pax 6

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8
Q

by inserting a human Pax6 gene into a fruitfly leg, what happens

A

the regulatory switch gene forms a fruitfly eye, not a human eye

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9
Q

as an embryo develops, a ________ system is formed

A

coordinate system

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10
Q

the _______ gene determines if you’re in the right anterior/posterior place

A

Hawkes gene

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11
Q

in embryonic development, information is received from info in the ____ and the _____

A

egg and genome

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12
Q

cells in development become _________ specialized

A

progressively

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13
Q

2 general ways that daughter cells can differentiate

A
  1. asymmetric division(intrinsic), cells are born different,;
  2. symmetric division(extrinsic), sister cells become different as result of influences acting on them after birth (close range signals)
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14
Q

proper spindle ________ is required for an asymmetric outcome

A

orientation

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15
Q

localization ofa cell fate determinant in yeast involves RNP particles, _______ and the _____ _________

A

a motor, actin cytoskeleton

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16
Q

yeast makes a mating type _____, with allows conjugation, restoring _______

A

switch, diploidy

17
Q

how is the switch in yeast initiated?

A

HO initiates the switch, by making a cut in the dna

18
Q

Ash1 ______ the expression of the nuclease (HO) in the daughter yeast cell

A

inhibits

19
Q

Ash1 is a _____ _______

A

transcriptional repressor

20
Q

asymmetric localization of ASH1 requires an _____ -______

A

actin cytoskeleton

21
Q

ORF

A

open reading frame

22
Q

UTR

A

untranslated region

23
Q

3’ UTR removal from ASH1 mrna ______ polar aggregation of rna

A

inhibited

24
Q

how is the ASH1 mRNA moved from one to side of the cell to another

A

myosin (myo4P) binds to She2 and She3 and carries the mRNA to one side of the cell by binding to a target sequence on the URT tail of the Ash1 mRNA