From Review Flashcards by M H | Brainscape

Q

Apc inhibits

A

Beta catenin

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Q

Ras activated by

A

GDP to Gtp

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Q

Gain of function (cancer)

A

Dominant / oncogene

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Q

Loss of function - cancer

A

Recessive / tumor suppressor

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Q

P53 activates ?

A

P21 and Bax

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Q

Does P53 suppress or encourage cell growth ?

A

Repress

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Q

Loss of gtpase activity on Ras will—?

A

Leave Ras activated and lead to cancer

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Q

Morula potency

A

Totipotent

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Q

Blastocyst potency

A

Pluripotent

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Q

Post gastrulation potency

A

Multipotency

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Q

Is wnt secreted ?

A

Yes! And localized

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