[2] Class 1-Lipids-Agbas Flashcards Preview

Biochemistry > [2] Class 1-Lipids-Agbas > Flashcards

Flashcards in [2] Class 1-Lipids-Agbas Deck (55)
Loading flashcards...
1

What is water insoluble but highly soluble in organic solvents?

Lipids

2

What is the key constituent of Lipids?

Fatty acids

3

What part of the lipid is responsible for hydrophobic properties?

Fatty acids

4

What makes lipids amphipathic?

Hydrophobic fatty acid tail

Hydrophilic phosphate head group

5

Unsaturated double bond in FA tail contributes 2 things:

Allows cholesterol to be in between 2 FA's and provides fluidity to the membrane

6

Proteins are modified by what attachment that allows them to target membranes

Covalent attachment of FA's

7

Functions of FA's:

Membrane component
Store fuel as triacylglycerols (TAG)
Derivatives serve as hormones, signal molecules, and Intracellular messengers

8

How do you number carbons in FA chain?

Starting at carboxyl terminus
OR
Omega begin counting at methyl carbon at distal end of the chain

9

Carbons 2 and 3 of fatty acid

alpha and beta

10

How to name fatty acids?

E changes to -oic.
Double bonds change
-ane to en to dien to trien

11

18:0
Vs
18:2

18 Carbon FA w/ no double bonds and :2= 2 double bonds

12

Fatty acids usually contain an _____ number of Carbon atoms, typically between ____ and ____ carbons

EVEN ; 14 and 24

13

What length FA's are most common?

16- and 18-

14

Configuration of the double bonds in most unsaturated FA's is

Cis

15

FA's are _______ at physiological pH

Ionized

16

What determines the properties of fatty acids?

Length of hydrocarbon chain

Degree of saturation

17

Relate melting point and unsaturated FA vs. saturated FA

Unsaturated has lower melting point...doesn't allow for tight packing

18

How is melting point affected when saturated FA increase w/ chain length?

M.P increases w/ increased chain length d/t more tight packing is possible w/ more carbon groups

19

Name the 3 essential FA's:

Linoleate
Linolenate
Arachidonate

20

Which EFA is not really a EFA?

Arachidonate

Can be manufactured by linolenate

21

What type of bond is found in archea that allows life in extreme environments? Why?

Ether bonds; they're more resistant to hydrolysis

They also have branched and saturated hydrocarbons- resistant to oxidation

22

3 major membrane lipids:

Phospholipids
Glycolipids
Cholesterol

23

2 types of phospholipids

Phosphoglyceride
Sphingomyelin

24

Major glycolipid:

Cerebroside

25

What are the 4 components of a phospholipid?

1 FA
2 A backbone
3 A phosphate
4 An alcohol

26

Which properties allow phospholipids to interact w/ the environment?

Hydrophilic properties of the phosphate and alcohol groups.

27

Name the simplest phosphoglyceride:

Phosphatidate

OR

Diacylglycerol 3-phosphate

28

What process is Phosphatidate or diacylglycerol 3-phosphate involved in?

It is a key intermediate in the biosynthesis of other phosphoglycerides

29

Is there a lot of Phosphatidate in membrane?

No only small amounts of phosphatidate are present in membranes

30

What is derived from Phosphatidate?

Phosphoglycerides