Flashcards in  Class 1-Lipids-Agbas Deck (55)
What is water insoluble but highly soluble in organic solvents?
What is the key constituent of Lipids?
What part of the lipid is responsible for hydrophobic properties?
What makes lipids amphipathic?
Hydrophobic fatty acid tail
Hydrophilic phosphate head group
Unsaturated double bond in FA tail contributes 2 things:
Allows cholesterol to be in between 2 FA's and provides fluidity to the membrane
Proteins are modified by what attachment that allows them to target membranes
Covalent attachment of FA's
Functions of FA's:
Store fuel as triacylglycerols (TAG)
Derivatives serve as hormones, signal molecules, and Intracellular messengers
How do you number carbons in FA chain?
Starting at carboxyl terminus
Omega begin counting at methyl carbon at distal end of the chain
Carbons 2 and 3 of fatty acid
alpha and beta
How to name fatty acids?
E changes to -oic.
Double bonds change
-ane to en to dien to trien
18 Carbon FA w/ no double bonds and :2= 2 double bonds
Fatty acids usually contain an _____ number of Carbon atoms, typically between ____ and ____ carbons
EVEN ; 14 and 24
What length FA's are most common?
16- and 18-
Configuration of the double bonds in most unsaturated FA's is
FA's are _______ at physiological pH
What determines the properties of fatty acids?
Length of hydrocarbon chain
Degree of saturation
Relate melting point and unsaturated FA vs. saturated FA
Unsaturated has lower melting point...doesn't allow for tight packing
How is melting point affected when saturated FA increase w/ chain length?
M.P increases w/ increased chain length d/t more tight packing is possible w/ more carbon groups
Name the 3 essential FA's:
Which EFA is not really a EFA?
Can be manufactured by linolenate
What type of bond is found in archea that allows life in extreme environments? Why?
Ether bonds; they're more resistant to hydrolysis
They also have branched and saturated hydrocarbons- resistant to oxidation
3 major membrane lipids:
2 types of phospholipids
What are the 4 components of a phospholipid?
2 A backbone
3 A phosphate
4 An alcohol
Which properties allow phospholipids to interact w/ the environment?
Hydrophilic properties of the phosphate and alcohol groups.
Name the simplest phosphoglyceride:
What process is Phosphatidate or diacylglycerol 3-phosphate involved in?
It is a key intermediate in the biosynthesis of other phosphoglycerides
Is there a lot of Phosphatidate in membrane?
No only small amounts of phosphatidate are present in membranes