2 - Derm - Skin + Systemic disease - Cutaneous small vessel vasculitis

Question 1

what is cutaneous small vessel vasculitis - also known as?

Answer 1

infl in blood vessel walls

leucocytoclastic vasculitis

Question 2

Features

• skin changes
• where
• ass features

Answer 2

palpable purpura
livedo reticularis
urticaria

back buttocks lower leg

malaise fever and wt loss common

Question 3

Triggers

Answer 3

infection - esp strep a (throat inf)
drugs - penicillin, nsaids, thiazides OCP, anticoags
systemic - SLE, RA, systemic vasculitis
malignancy

Question 4

Henoch-Schonlein purpura (HSP) - how different to other subtypes?

• common in?
• skin change? +where

Answer 4

• ANCA -ve
• common in young males
• vasculitic rash on buttocks/legs

Question 5

Henoch Schonlein purpura

• ass w?
• other Sx

Answer 5

commonly with throat/rep infection

arthralgia, abdo pain, haematuria, glomerulonephritis

Question 6

Investigations for Cut small vessel vasculitis

-7 things

Answer 6

FBC, ESR/CRP, U+E (renal involvement), LFT (hep involvement), CXR (pulm involvement)
Throat swab (ASO titre)
Autoantibodies - ANCA, ANA, RhF

Question 7

mgmt

Answer 7

rest and elevate
analgesia
corticosteroids + immsuppressants in severe