– Durg Release
– Release of drug from the dosage form
Liberation
End product of Liberation
Drug in AQUEOUS solution
Pharmacotechnical Factors (Solid Dosage Forms)
Governing Principle of Liberation
NOUES-Whitney Equation (Dissolution Rate)
– Highly Modifiable
– Modified Release Dosage Forms
* Delayed Release
Extended Release
* Prolonged Release — Slowly over time
Delayed Release
Enteric Coated