2.5 cell membranes Flashcards

(38 cards)

1
Q

no. membranes around nucleus

A

2

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2
Q

no. membranes around ER

A

1

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3
Q

no. membranes around GOLGI

A

1

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4
Q

no. membranes around LYSOSOME

A

1

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5
Q

no. membranes around CHLOROPLAST

A

2

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6
Q

no. membranes around MITOCHONDRIA

A

2

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7
Q

partially permeable defintion

A

allows some substances to pass through but not all

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8
Q

purpose of plasma membrane

A
  1. BARRIER : controls movement of substances in and out of the cell (cell membrane)
  2. Compartmentalisation (golgi apparatus)
  3. cell signalling (receptors on csm)
  4. electrical communication (nerve csm)
  5. attachment site for enzymes (inner membrane of mitochondria)
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9
Q

phopholipid properties

A
  • hydrophilic head (charged)
  • hydrophobi tails (uncharged)
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10
Q

phospholipid bilayer orientation

A

orientate so that hypdrophilic heads are faced towards water and hydrophobic tails away from water
- can form a micelle (sphere) HPI heads outside and in the middle

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11
Q

7 components of CSM

A
  1. glycoprotein
  2. glycoplipid
  3. phospholipid bilayer
  4. cholestrol
  5. channel / carrier protein
  6. extrinsic protein
  7. actin microfilament
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12
Q

fluid mosaic model

A
  • phospholipid bilayer
  • hydophilic heads facing external environment
  • hydophobic tails away from external environment
  • proteins free to move inside membrane
  • proteins randomly arranged throughouy
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13
Q

cholestrol

A
  • 4 carbon rings
  • regulates fluidiity of membrane
  • ONLY IN EUKARYOTIC
  • high temp: binds to tails of phospholipids, increasing packing reducing fluidity
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14
Q

channel proteins

A
  • ALLOW facilitated diffusion to happen
  • only specific substances can diffuse through
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15
Q

carrier proteins

A
  • change shape to allow specific substances through
  • facilitated diffusion AND active transport
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16
Q

glycoproteins and glycolipids

A
  • polysaccharaide chain attached to lipid or protein
  • act as antigens for cell recognition (tissue formation)
  • receptors for cell signalling
17
Q

temperature effect on membranes

A
  • as temp increaes, KE increases
  • membrane bceoms more fluid
  • gaps created
  • more permeable
18
Q

organisms in COLD environments membranes

A
  • MORE cholestrol to prevent membrane freezing
  • more UNSATURATED and SHORTER fatty acid tails to make it more fluid
19
Q

organisms in HOT environments membrane adaptation

A
  • more SATURATED and LONGER fatty acid tails to make membrane less fluid
20
Q

role of membrane bound receptors for hormones and drugs to bind

A
  1. glycoprotein or glycolipid receptors on the outer surface of csm has a BINDING SITE complementary in shape to the hormone or drug
  2. hormone or drug is primary messenger. binds to the receptor activating g proteins -> adenyl cyclase ->atp to camp
  3. camp secondary messenger, activates proteins by activating pka, phosphorylates. binding can also change shape
21
Q

what can diffuse across with simple diffusion?

A
  • small
  • non polar
  • FAT SOLUBLE (eg lipid) molecules
22
Q

channel proteins are involved in

A

facilitated diffusion

23
Q

carrier proteins are involved in

A

(facilitated diffusion) AND active transport

24
Q

endocytosis transports …

A

bulk transport of materials into the cell

25
describe endocytosis
1. molecule binds to specific comp receptor (glycprotein or glycolipid) on cell surface membrane and folds in around the substance 2. fuses with itself and pinches off, forming a vesicle 3. vesicle moves through cytoplasm 4. USES ATP
26
how does the active transport using proteins work
- carrier protein changes shape using ATP - AT pump (protein) is shaped so that the molecule being carried fits to one side only
27
how to describe permeability when using the proteins
selectively permeable
28
extrinsic proteins
proteins held on the outer surface of the membrane
29
2 examples of what cannot go across by simple diffusion
- water - ions
30
how does cholestrol work
- fits between the tails of phospholipids - inhibits their movement, reducing fluidity
31
waht happens if the temp is too high
- loses mechanical stability - fully permeable - proteins denature
32
effect of solvents like alcohol
- dissolve fatty substances by inserting into bilayer and breaking IMFs
33
OTHER use of cholestrol
steroid hormones - make vitamin D - make bile salts
34
3 example of active transport
- mineral ions into root hair cells - h+ out of companion cells - sucrose out of sieve tube at sink
35
freezing effect on permeability
increases
36
how does x pass through membrane
- non-polar lipid - soluble in the phospholipid bilayer so can pass through
37
why is rate of transport not constant in active transport
- uses carrier proteins - proteins become saturated
38
exocytosis
bulk transport of substances OUT of the cell - component packaged into vesicle - vesicle fuses w cell surface membrane - released outside - requires ATP