27. Anaerobic Gram-positive Bacillus Flashcards Preview

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Flashcards in 27. Anaerobic Gram-positive Bacillus Deck (24):
1

Location of spores produced by Clostridium spp.

Terminal or central

2

Clostridium spp. that causes gas gangrene and food poisoning

Clostridium perfringens

3

Clostridium spp. that causes tetanus

Clostridium tetani

4

Clostridium spp. that causes botulism

Clostridium botulinum

5

Clostridium spp. that causes antibiotic-associated diarrhea and colitis

Clostridium difficile

6

Motility of C. perfringens

Nonmotile

7

Disease caused by C. perfringens

Gas gangrene
Food poisoning

8

Motility of C. tetani

Motile

9

Disease caused by C. tetani

Tetanus

10

Treatment for gas gangrene caused by C. perfringens

Hyperbaric O2 chamber
Antibiotics
Surgical (debridement)

11

Treatment of Tetanus

Antitoxin

12

Prophylaxis for tetanus

Vaccination (toxoid)

13

Motility of C. botulinum

Motile

14

Toxin produced by C. botulinum

Botulism neurotoxin (BoTN)

15

Mechanism of botulism neurotoxin

Blocks Ach release at the neuromuscular junction and causes inhibition of muscle contraction

16

How to destroy Botulinum toxin in food?

Boiling the food

17

MOT of infant botulism

Ingestion of food containing spores

18

Most common food source of C. botulinum spores

Honey

19

Motility of C. difficile

Motile

20

Enterotoxins released by C. difficile

A and B

21

Disease caused by C. difficile

Pseudomembranous colitis/antibiotic-associated colitis

22

Treatment for pseudomembranous colitis

Metronidazole
Vancomycin

23

Diagnostic tests for pseudomembranous colitis

- immunoassay of stool extract for C. difficile toxins
- colonoscopy showing pathologic findings of pseudomembranous colitis

24

Microscopic characteristics of Clostridium spp.

Gram-positive bacillus
(usually large bacilli)