3 - Derm - Benign and Malignant Melanocytic lesions - Melanoma 1 Flashcards Preview

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Flashcards in 3 - Derm - Benign and Malignant Melanocytic lesions - Melanoma 1 Deck (11):
1

incidence of melanoma
slightly more common in who
% of skin cancer deaths?

~10/10000
women
80

2

RFs for melanoma

UV exposure
fair skin
FHx
immunosuppression
large congenital naevi
old age
multiple atypical naevi

3

Clinical features - Glasgow 7 point checklist - maj points

major point/3 minors = suspicion

maj -
1 - irregular shape/asymmetry
2 - changing or irregular colour
3 - changing size

4

Clinical features - Glasgow 7 point checklist - min points

min-
4 - oozing/crusting/bleeding
5- sensation change, itching
6- inflammation
7- largest diameter >7mm

5

types of melanoma - 4 overall types

Acral
nodular
superficial spreading
lentigo/lento maligna

6

Lento maligna - what happens, where? begins as? duration?

malignant proliferation of melanocytes confined to epidermis
at sun exposed sites
begins as large freckle
long history

7

Lento maligna - peak age? ass w? not ass w?

60-80
ass w UV exp
not ass w pre existing naevi

8

Lento maigna - features - 4

large (>6mm)
irregular border
variable colour
smooth surface

9

Lento maligna - mgmt

surgical excision with 5mm margin

10

Lentigo maligna melanoma - dif from lento?

when malignant cells invade dermis - 3-10%

11

Lentigo maligna melanoma - features

thickening of lesion - can become nodular
variability in colours (blue, black)
2ndary features - ulceration bleeding, itching, stinging

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