Flashcards in 3.5 Infections in Immunocompromised hosts Deck (10):
What are the physiologic causes of immunocomprimise?
What are the macroscopic barriers to immunodeficiency and what breaches them?
Skin - surgical wounds, eczema
Mucous membranes - mucositis
Foreign materials - Catheters
What are the surface barriers in the body?
Mucociliary elevator in lungs
Normal flora in genital tract
Bile acid in GI tract
Tears in eyes
Acids and desquamation in skin
What cells are involved in extracellular bacteria infection?
Phagocytes, B cells > CD4 T cells
What cells are involved in Viral infections?
CD8 T cells > NK cells >> CD4 t cells, B cells and phagocytes
What cells are involved in fungal infections?
Phagocytes > CD4 T cells >> B cells
What cells are involved in intracellular bacterial infections?
Phagocytes and CD4 T cells
What are the bacterial intracellular pathogens?
Salmonella, listeria, Nocardia, Legionella, Rickettsia, Mycoplasma
what are the fungal, viral and parasite intracellular pathogens?
Fungal: cryptotoccus, pneumocystis