3.5 Infections in Immunocompromised hosts Flashcards Preview

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Flashcards in 3.5 Infections in Immunocompromised hosts Deck (10):
1

What are the physiologic causes of immunocomprimise?

Very young
Pregnant
Very old

2

What are the macroscopic barriers to immunodeficiency and what breaches them?

Skin - surgical wounds, eczema
Mucous membranes - mucositis
Foreign materials - Catheters

3

What are the surface barriers in the body?

Stomach acid
Mucociliary elevator in lungs
Normal flora in genital tract
Bile acid in GI tract
Tears in eyes
Acids and desquamation in skin

4

What cells are involved in extracellular bacteria infection?

Phagocytes, B cells > CD4 T cells

5

What cells are involved in Viral infections?

CD8 T cells > NK cells >> CD4 t cells, B cells and phagocytes

6

What cells are involved in fungal infections?

Phagocytes > CD4 T cells >> B cells

7

What cells are involved in intracellular bacterial infections?

Phagocytes and CD4 T cells

8

What are the bacterial intracellular pathogens?

Salmonella, listeria, Nocardia, Legionella, Rickettsia, Mycoplasma

Most facultative

9

what are the fungal, viral and parasite intracellular pathogens?

Fungal: cryptotoccus, pneumocystis

Viral: Herpes

Parasite: Toxoplasma

10

What are the three factors of diagnosing an infection?

HOST EXPOSURE SYNDROME