Flashcards in 5.6 Female Genitourinary Tract Pathology Deck (21):
What are deposits in the urinary bladder called?
Within lumen: Lithiasis
Within wall: Amyloid
What are the benign and malignant neoplasms of Flat urothelial cells?
Benign: regenrative changes following inflammation
Malignant: Carcinoma in situ and Urothelial carcinoma
How can you tell the difference between CIS and urothelial carcinoma?
CIS will not have invaded past the BM
What is the treatment for CIS and urothelial carcinoma?
CIS: transurethral resection and intravesical BSG
Urothelial carcinoma: Cystectomy
What is the sturucture of a papilla?
Finger like projection with a core of blood vessels and connective tissue surrounded by epithelium
What are the benign and malignant neoplasms of papillary cells of the urothelium?
Malignant: Papillary urothelial carcinoma
What will you see histologically in papillary urothelial carcinoma?
Lined by cytologically malignant epithelium
Increased thickness of urothelium
Complete loss of organisation
What is inflammation/infection of the fallopian tube known as?
What is the macro appearance of salpingitis?
Adhesion and fusion of fimbriae
Dilated tube filled with pus
What is the micro appearance of salpingitis?
Acute or chronic inflammation
What are the complications of salpingitis?
What is the appearance of ectopic pregnancy?
Fallopian tubes distended with ruptured walls
Macro: dilated, haemorrhage, may have fetus
Micro: chorionic villi
What is the term for endometrium in the wrong location?
Endometriosis: otuside the uterus
Adenometriosis: within myometrium
What is the appearance of endometrial carcinoma?
Glands arranged back to back without intervening normal stroma.
The glands and papillae are lined by multiple layers of cells
Cells show large nuclei with neucleoli, altered nuclear/cytoplasmic ratio and pleomorphism
What is leiomyoma and what is its appearance?
smooth muscle proliferation with homogenous, whirled appearance
What are the complications of leiomyoma?
pain, mennorrhagia, compressive symptoms, infertility
What are the malignant conditions of the cervix?
SCC and adenocarcinoma
What are the malignant conditions of the vagina?
SCC, clear cell carcinoma, embryonal rhabdomyosarcoma
What lines the vulva?
stratified keratinising squamous epithelium
What is leukoplakia?
A white plaque like thickening of the mucosa which can be benign (Lichen sclerosis) or malignant (early SCC)