5.6 Female Genitourinary Tract Pathology Flashcards Preview

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Flashcards in 5.6 Female Genitourinary Tract Pathology Deck (21):
1

What are deposits in the urinary bladder called?

Within lumen: Lithiasis
Within wall: Amyloid

2

What are the benign and malignant neoplasms of Flat urothelial cells?

Benign: regenrative changes following inflammation
Malignant: Carcinoma in situ and Urothelial carcinoma

3

How can you tell the difference between CIS and urothelial carcinoma?

CIS will not have invaded past the BM

4

What is the treatment for CIS and urothelial carcinoma?

CIS: transurethral resection and intravesical BSG

Urothelial carcinoma: Cystectomy

5

What is the sturucture of a papilla?

Finger like projection with a core of blood vessels and connective tissue surrounded by epithelium

6

What are the benign and malignant neoplasms of papillary cells of the urothelium?

Benign: Papilloma
Malignant: Papillary urothelial carcinoma

7

What will you see histologically in papillary urothelial carcinoma?

Lined by cytologically malignant epithelium
Increased thickness of urothelium
Complete loss of organisation
Several mitoses

8

What is inflammation/infection of the fallopian tube known as?

Salpingitis

9

What is the macro appearance of salpingitis?

Adhesion and fusion of fimbriae
Dilated tube filled with pus

10

What is the micro appearance of salpingitis?

Acute or chronic inflammation
Pilcea fused

11

What are the complications of salpingitis?

Abscess formation
Ectopic pregnancy
Infertility

12

What is the appearance of ectopic pregnancy?

Fallopian tubes distended with ruptured walls

Macro: dilated, haemorrhage, may have fetus

Micro: chorionic villi

13

What is the term for endometrium in the wrong location?

Endometriosis: otuside the uterus
Adenometriosis: within myometrium

14

What is the appearance of endometrial carcinoma?

Glands arranged back to back without intervening normal stroma.
The glands and papillae are lined by multiple layers of cells

Cells show large nuclei with neucleoli, altered nuclear/cytoplasmic ratio and pleomorphism

15

What is leiomyoma and what is its appearance?

smooth muscle proliferation with homogenous, whirled appearance

16

What are the complications of leiomyoma?

pain, mennorrhagia, compressive symptoms, infertility

17

What are the malignant conditions of the cervix?

SCC and adenocarcinoma

18

What are the malignant conditions of the vagina?

SCC, clear cell carcinoma, embryonal rhabdomyosarcoma

19

What lines the vulva?

stratified keratinising squamous epithelium

20

What is leukoplakia?

A white plaque like thickening of the mucosa which can be benign (Lichen sclerosis) or malignant (early SCC)

21

What is the micro and macro appearance of lichen sclerosis?

Macro: an area of leukoplakia
Micro: hyperkeratosis, thinning of epidermis, loss of rete pegs and dermal collagen altered