3B and 3C Flashcards
(38 cards)
Rosalind Franklin
the structure of DNA - Franklin’s X-ray and creation of the Photo of the double-helix structure
Watson & Crick
proposed the double helix structure of DNA by building it. stole franklin’s light
DNA function
store and transmit genetic information, acting as the blueprint for all living organisms and viruses.
Chargaff’s Rules
A=T and G=C
DNA structure
a double-stranded molecule with a twisted ladder shape known as a double helix. Dna is a nucleic acid made up of nucleotides
bases of DNA vs RNA
Adenine, thymine, guanine, cytosine vs Adenine, uracil, guanine, cytosine
Purpose of DNA replication
to produce two identical copies of a DNA molecule,so each new cell receives a complete set of genetic information
replication fork
Y-shaped structure formed during DNA replication where the double-stranded DNA helix is separated
Topoisomerase
enzymes that unwinds dna BUT DOSENT SEPERATE for helicase to follow
DNA helicase
an enzyme that unzips the double-stranded DNA helix, separating the two strands
DNA polymerase
enzymes that create DNA molecules by assembling nucleotides
DNA ligase
enzymes that fills the junctions between okazaki fragments and primer
RNA primer
short stretches of RNA that provide a starting point for DNA polymerase to begin synthesizing a new DNA strand
Okazaki fragment
short, newly synthesized DNA sequences on the lagging strand during DNA replication formed by polymerase
leading vs lagging strand
the leading strand is synthesized continuously and goes from 3’ to 5’, while the lagging strand is synthesized in short, discontinuous fragments called Okazaki fragments going from 5’ to 3’
Similarities and differences between RNA & DNA
DNA is double-stranded, utilizes deoxyribose sugar, and contains thymine, while RNA is single-stranded, uses ribose sugar, and contains uracil instead of thymine
mRNA
carries genetic info from nucleus to ribosome
Trna
serves as a link between the mRNA and the growing chain of amino acids that make up a protein.
rRNA
form ribosome and catalyzing the formation of peptide bonds between amino acids
intron
non coding sequences that are removed
exons
a segment of a DNA or RNA molecule containing information coding for a protein or peptide sequence.
RNA splicing/editing
processes that modify pre RNA transcripts by removing introns. after transcription but still in the nucleus
Substitution mutation
change in a single nucleotide base in a DNA sequence. ONLY A GENE/POINT mutation
Insertion mutation
one or more nucleotide base pairs are added into the DNA sequence. could result to frameshift.ONLY A GENE/POINT mutation