3b- LABAs

Question 1

What are 3 ways LABAs differ from SABAs?

Answer 1

1. Chemical structore
2. Length of onset + Duration (Slower + longer)
3. Main goals of use (longer relief + symptom prevention)

Question 2

What are 4 LABA Drugs?

SOVO

Answer 2

1. Serevent
2. Oxeze (Formoterol)
3. Vilanterol
4. Onbrez (Indacaterol)

Question 3

Severent

Describe its times

Answer 3

• Onset –> 15-20min
• Peak –> 3-5hrs
• Duration –> 12hrs

Question 4

Oxeze (Formoterol)

Describe its times + 2 special things about this drug

Answer 4

• Onset –> 5min
• Peak –> 30-60min
• Duration –> 12hrs

1. SMART Treatment Approach
2. GINA Recommendation

Question 5

Vilanterol

What is it classified as? What is its duration time? When can it only show up?

Answer 5

• Ultra Long LABA
• Duration –> 24hrs
• Only shows up in COMBINATION FORM

Question 6

Onbrez (Indacaterol)

Describe its times

Answer 6

• Onset –> ~5min
• Peak –> 15-120min
• Duration –> 24hrs (Ultra Long LABA)

Question 7

Onbrez (Indacaterol)

What is its primary use?

Answer 7

• Maintenance therapy for moderate to severe COPD
• ↑Lung function + ↓dyspnea

Question 8

Onbrez (Indacaterol)

What are its side effects? (4)

Answer 8

1. Tremor/Headache
2. Tachycardia
3. Hypokalemia
4. Cough

Question 9

Symbicort

What is this drug composed of?

Answer 9

Budesonide + Formoterol

Question 10

Symbicort (Budesonide + Formoterol)

What is special about it?

Answer 10

• SMART Drug

Question 11

What are LABAs primarily used for?

Answer 11

1. COPD + Asthma Treatment Plans
2. Long Term Prevention + Maintenance of Symptoms

Question 12

What happens if you use a LABA w/o an ICS?

Answer 12

• It masks airway inflammation
• Delays care + worsens outcomes