4: Acute liver disease and fulminant hepatic failure Flashcards Preview

Gastrointestinal Week 6 2016/17 > 4: Acute liver disease and fulminant hepatic failure > Flashcards

Flashcards in 4: Acute liver disease and fulminant hepatic failure Deck (15)
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1

What is acute liver disease?

Rapid onset of liver dysfunction without prior liver disease

2

The liver has ___ potential.

regenerative

3

Which two blood vessels supply the liver?

Hepatic arteries

Hepatic portal vein

4

What percentage of blood is supplied to the liver by the hepatic portal vein?

70%

5

By which great vessel does deoxygenated blood leave the liver?

Inferior vena cava

6

By which vessel does bile leave the liver and gall bladder?

Bile duct

7

What are the cardinal features of acute liver disease?

Encephalopathy

Increased coagulation time

8

What are some symptoms of acute liver disease?

JAUNDICE!!!

Lethargy

Nausea

Anorexia

Pain

Itching

Arthralgia

9

What are some causes of acute liver disease?

Viruses (Hepatitis, EBV, CMV)

Drugs (ask about paracetamol)

Alcohol

Malignancy

Shock liver

Cholangitis

10

How is acute liver disease treated?

Rest (up to 3 months)

Fluids

Try to increase calories (not fat-rich foods)

11

How can itching associated with acute liver disease be treated?

Sodium bicarbonate bath

Bile salt sequestrants

Ursodeoxycholic acid

12

Which drugs can cause liver disease?

Antibiotics (co-amoxiclav, flucloxacillin, NSAIDs)

Paracetamol

13

What is fulminant liver failure?

Hepatic failure < 8 weeks after onset of symptoms

basically the same as acute liver failure, but really fast

14

Fulminant liver failure should be treated ___ and may result in a liver ___.

quickly

transplant

15

What are the most common causes of fulminant liver failure?

Paracetamol overdose

Viruses e.g Hepatitis B