What is acute liver disease?
Rapid onset of liver dysfunction without prior liver disease
The liver has ___ potential.
Which two blood vessels supply the liver?
Hepatic portal vein
What percentage of blood is supplied to the liver by the hepatic portal vein?
By which great vessel does deoxygenated blood leave the liver?
Inferior vena cava
By which vessel does bile leave the liver and gall bladder?
What are the cardinal features of acute liver disease?
Increased coagulation time
What are some symptoms of acute liver disease?
What are some causes of acute liver disease?
Viruses (Hepatitis, EBV, CMV)
Drugs (ask about paracetamol)
How is acute liver disease treated?
Rest (up to 3 months)
Try to increase calories (not fat-rich foods)
How can itching associated with acute liver disease be treated?
Sodium bicarbonate bath
Bile salt sequestrants
Which drugs can cause liver disease?
Antibiotics (co-amoxiclav, flucloxacillin, NSAIDs)
What is fulminant liver failure?
Hepatic failure < 8 weeks after onset of symptoms
basically the same as acute liver failure, but really fast
Fulminant liver failure should be treated ___ and may result in a liver ___.
What are the most common causes of fulminant liver failure?
Viruses e.g Hepatitis B