4: Concepts in infection 2 Flashcards Preview

CLASP: Sepsis 2017/18 > 4: Concepts in infection 2 > Flashcards

Flashcards in 4: Concepts in infection 2 Deck (16)
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1

- patient looks ill

- early warning score

- sign of infection

= sepsis

2

Where is the site of infection?

Where the inflammation is

3

What factors affect how a host responds to infection?

Age

Immunosuppression

Drugs

Genetics

4

What are some examples of deep infections which are difficult to identify?

Endocarditis (generally unwell)

Osteomyelitis

5

A NEWS2 score of >= __ indicates sepsis.

>= 5

6

Once you've taken a history, examined and decided where the infection is, what do you do?

Investigations

7

What must be done with any abscess or pus?

Drained (+/- by surgery)

antibiotics don't penetrate it

8

What indicates spontaneous peritonitis?

Ascites

9

What indicates secondary bacterial peritonitis?

History (e.g trauma, perforated bowel)

10

Which organisms colonise the mouth?

Strep viridans

Neisseria spp.

Anaerobes

Some Candida and Staph

11

What organisms colonise the colon?

Coliforms:

E. coli, Klebsiella, Enterobacter

12

Are the bile ducts colonised by bacteria?

No

13

workhorse for coliforms, i.e gram -ves is gentamicin, alternative is aztreonam IV

step down is oral co-trimoxazole

don't use ciprofloxacin - C diff

14

notable anaerobes:
 clostridium - diff (4 cs), perfringens (gas gangrene), botulinum (botulism)

bacteroides (not really)

metronidazole

15

MRSA isn't killed by fluclox (related to methicillin)

16

take peritonitis:

amoxicillin for enterococci

gentamicin for gram negatives (coliforms)

metronidazole for anaerobes