4: Concepts in infection 2 Flashcards Preview

CLASP: Sepsis 2017/18 > 4: Concepts in infection 2 > Flashcards

Flashcards in 4: Concepts in infection 2 Deck (16)
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1
Q
  • patient looks ill
  • early warning score
  • sign of infection

= sepsis

A
2
Q

Where is the site of infection?

A

Where the inflammation is

3
Q

What factors affect how a host responds to infection?

A

Age

Immunosuppression

Drugs

Genetics

4
Q

What are some examples of deep infections which are difficult to identify?

A

Endocarditis (generally unwell)

Osteomyelitis

5
Q

A NEWS2 score of >= __ indicates sepsis.

A

>= 5

6
Q

Once you’ve taken a history, examined and decided where the infection is, what do you do?

A

Investigations

7
Q

What must be done with any abscess or pus?

A

Drained (+/- by surgery)

antibiotics don’t penetrate it

8
Q

What indicates spontaneous peritonitis?

A

Ascites

9
Q

What indicates secondary bacterial peritonitis?

A

History (e.g trauma, perforated bowel)

10
Q

Which organisms colonise the mouth?

A

Strep viridans

Neisseria spp.

Anaerobes

Some Candida and Staph

11
Q

What organisms colonise the colon?

A

Coliforms:

E. coli, Klebsiella, Enterobacter

12
Q

Are the bile ducts colonised by bacteria?

A

No

13
Q

workhorse for coliforms, i.e gram -ves is gentamicin, alternative is aztreonam IV

step down is oral co-trimoxazole

don’t use ciprofloxacin - C diff

A
14
Q

notable anaerobes:
clostridium - diff (4 cs), perfringens (gas gangrene), botulinum (botulism)

bacteroides (not really)

metronidazole

A
15
Q

MRSA isn’t killed by fluclox (related to methicillin)

A
16
Q

take peritonitis:

amoxicillin for enterococci

gentamicin for gram negatives (coliforms)

metronidazole for anaerobes

A