READ ME / 1: Introduction to sepsis Flashcards Preview

CLASP: Sepsis 2017/18 > READ ME / 1: Introduction to sepsis > Flashcards

Flashcards in READ ME / 1: Introduction to sepsis Deck (37)
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1
Q

Thanks for using my flashcards, hope you find them useful!

If you spot any errors or have suggestions, please let me know by clicking the speech bubble or sending me a message. It’s really helpful.

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2
Q

The questions are written using the official Dundee lectures, so you might find it useful to have them open in the background in case you get stuck.

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3
Q

I write the questions based on what I think the important facts are, but not everything is relevant. Don’t waste your time learning tiny details.

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4
Q

On the other hand, this isn’t everything you need to know - back it up with stuff from tutorials, other people’s questions, Youtube videos, Oxford handbooks etc.

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5
Q

There’s a good chance that older decks will be inaccurate (lectures and guidelines change year to year) so I’ll try to update them in the future.

Break a leg 👍

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6
Q

What should be eliminated in any patient with an infection?

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Sepsis

7
Q

What does colonisation mean?

A

Microbe in the body WITHOUT an inflammatory response

e.g Staph aureus on the skin

8
Q

What is infection?

A

Inflammatory response due to a microbe

9
Q

What is bacteraemia?

A

Presence of viable bacteria in the blood

10
Q

What is septicaemia?

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A duff term that shouldn’t be used

11
Q

What is the definition of sepsis?

A

Life-threatening organ dysfunction caused by dysregulated host response to infection

12
Q

What is the definition of septic shock?

A

Circulatory / metabolic dysfunction secondary to sepsis

i.e the patient cannot be adequately resuscitated

13
Q

___ is a subset of ___.

(sepsis, septic shock)

A

Septic shock is a subset of sepsis

14
Q

People with septic shock have a much higher mortality and should be admitted to…

A

intensive care

15
Q

Sepsis has distinct ___ and ___.

A

signs and symptoms

16
Q

What is an abdominal infection caused by leakage of bowel contents into the peritoneal cavity?

A

Peritonitis

17
Q

general signs and symptoms of sepsis

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18
Q

What needs to be determined re: sepsis to treat it properly?

A

Severity

19
Q

How does sepsis cause organ dysfunction?

A

Bacteraemia causes leaky blood vessels

> ischaemia, infarction

20
Q

What is SIRS?

Is it in favour anymore?

A

Systemic inflammatory response syndrome

No, NEWS or qSOFA criteria used now

21
Q

Is SIRS specific to infection?

A

No, caused by trauma, pancreatitis…

But all patients with sepsis fulfill the SIRS criteria

22
Q

Apart from infection, what are some other causes of SIRS?

A

Trauma (especially polytrauma)

Burns

Pancreatitis

23
Q

What are the SIRS criteria?

A

T > 38 or < 36

HR > 90bpm due to leaky vessels > insufficient perfusion

RR > 20/min due to perceived hypoxia

Raised or reduced WBCs

24
Q

With regard to SIRS criteria, what is sepsis?

A

2+ fulfilled SIRS criteria with KNOWN INFECTION

25
Q

What is septic shock with regard to SIRS criteria?

A

2+ fulfilled SIRS criteria

Known infection

Organ dysfunction

Hypotension despite fluid resuscitation

26
Q

As sepsis progresses to septic shock, mortality ___.

A

increases

27
Q

How do you remember the Sepsis 6 bundle of treatment?

A

BUFALO

Give three, take three

(Take blood, urine output, lactate. Give fluids, oxygen and antibiotics.)

28
Q

What is SOFA?

A

Sequential organ function assessment

A scoring system for sepsis

29
Q

When is the actual SOFA score used?

A

ICU

when you have access to loads of information

30
Q

What is the abbreviated version of the SOFA score?

A

qSOFA

31
Q

What are the three criteria in the qSOFA score?

A

RR > 22/min

sBP < 100mgHg

Altered GCS

32
Q

The higher your qSOFA score, the greater your ___.

A

mortality

33
Q

qSOFA:

Respiratory rate > __ / min

sBP < ___ mmHg

GCS < __

A

RR > 20/min

sBP < 100 mmHg

GCS < 14

34
Q

How does the NHS score patients at risk of sepsis?

A

NEWS2 score

35
Q

A NEWS2 score of > __ and __ is diagnostic of sepsis.

A

NEWS2 > 5

confirmed infection

36
Q

The higher your NEWS2 score, the poorer your ___.

A

prognosis

37
Q

NEWS2 and ___ scoring tend to agree with one another.

A

qSOFA