READ ME / 1: Introduction to sepsis Flashcards Preview

CLASP: Sepsis 2017/18 > READ ME / 1: Introduction to sepsis > Flashcards

Flashcards in READ ME / 1: Introduction to sepsis Deck (37)
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1

Thanks for using my flashcards, hope you find them useful!

If you spot any errors or have suggestions, please let me know by clicking the speech bubble or sending me a message. It's really helpful.

2

The questions are written using the official Dundee lectures, so you might find it useful to have them open in the background in case you get stuck.

3

I write the questions based on what I think the important facts are, but not everything is relevant. Don't waste your time learning tiny details.

4

On the other hand, this isn't everything you need to know - back it up with stuff from tutorials, other people's questions, Youtube videos, Oxford handbooks etc.

 

5

There's a good chance that older decks will be inaccurate (lectures and guidelines change year to year) so I'll try to update them in the future.

Break a leg 👍

6

What should be eliminated in any patient with an infection?

Sepsis

7

What does colonisation mean?

Microbe in the body WITHOUT an inflammatory response

e.g Staph aureus on the skin

8

What is infection?

Inflammatory response due to a microbe

9

What is bacteraemia?

Presence of viable bacteria in the blood

10

What is septicaemia?

A duff term that shouldn't be used

11

What is the definition of sepsis?

Life-threatening organ dysfunction caused by dysregulated host response to infection

12

What is the definition of septic shock?

Circulatory / metabolic dysfunction secondary to sepsis

i.e the patient cannot be adequately resuscitated

13

___ is a subset of ___.

(sepsis, septic shock)

Septic shock is a subset of sepsis

14

People with septic shock have a much higher mortality and should be admitted to...

intensive care

15

Sepsis has distinct ___ and ___.

signs and symptoms

16

What is an abdominal infection caused by leakage of bowel contents into the peritoneal cavity?

Peritonitis

17

general signs and symptoms of sepsis

18

What needs to be determined re: sepsis to treat it properly?

Severity

19

How does sepsis cause organ dysfunction?

Bacteraemia causes leaky blood vessels

> ischaemia, infarction

20

What is SIRS?

Is it in favour anymore?

Systemic inflammatory response syndrome

No, NEWS or qSOFA criteria used now

21

Is SIRS specific to infection?

No, caused by trauma, pancreatitis...

But all patients with sepsis fulfill the SIRS criteria

22

Apart from infection, what are some other causes of SIRS?

Trauma (especially polytrauma)

Burns

Pancreatitis

23

What are the SIRS criteria?

T > 38 or < 36

HR > 90bpm due to leaky vessels > insufficient perfusion

RR > 20/min due to perceived hypoxia

Raised or reduced WBCs

24

With regard to SIRS criteria, what is sepsis?

2+ fulfilled SIRS criteria with KNOWN INFECTION

25

What is septic shock with regard to SIRS criteria?

2+ fulfilled SIRS criteria

Known infection

Organ dysfunction

Hypotension despite fluid resuscitation

26

As sepsis progresses to septic shock, mortality ___.

increases

27

How do you remember the Sepsis 6 bundle of treatment?

BUFALO

Give three, take three

(Take blood, urine output, lactate. Give fluids, oxygen and antibiotics.)

28

What is SOFA?

Sequential organ function assessment

A scoring system for sepsis

29

When is the actual SOFA score used?

ICU

when you have access to loads of information

30

What is the abbreviated version of the SOFA score?

qSOFA