41. Fracture biology_biomechanics Flashcards Preview

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Flashcards in 41. Fracture biology_biomechanics Deck (36):

T/Fbone is stronger when loaded rapidly than when loaded slowly

TRUEbone is stronger when loaded rapidly than when loaded slowly (viscoelastic)


bone mechanical property of anisotropy

mechanical properties of bone strongly depend on the direction of loadingfor example, long bones are stronger and better resist forces placed along the long axis than those across the axis.


stress vs strain

stress (y axis): force per unit area (N/meter ^2)strain (x axis): local deformation (units of length/length) or the change in unit length over original length (usually a percentage)


strength vs stiffness of a material

strength: ultimate load a material can withstand before ultimate failurestiffness: RATE at which material deforms when the load is applied; slope of the ascending linear portion of the stress/strain curve; aka elastic modulus


stress/strain curve vs load/displacement curve

stress/strain curve----materialsload/displacement----structures/fractures


yield point

Ypoint at which strain exceeds the materials ability to recoverrender the material permanently deformed


plastic vs elastic deformation

elastic deformation--reversible deformation before yield point is reached, material can recover to original formplastic deformation--irreversible deformation past the yield point where strain exceeds the materials ability to recover


failure point

Umaterial can no longer withstand strain and fails


cortical bone material properties (3)

anisotropic--stronger when loaded longitudinallybrittle--plastic deformation phase is steep/short viscoelastic --more rapid it is loaded, the stiffer it becomespizoelastic--as bone deforms it produces an electrical charge; compression is NEG (osteoblasts), tension is POS (osteoclasts)


cancellous bone material properties (

porosity--75-95% make it weaker and more compliantless stiff and lower yield point than cortical boneshort elastic phase, long plastic phase (from collapse of trabeculae)


what happens to stress when the surface area is decreased by one half

stress = force/meters squared (N/m^2)when area is decreased by 1/2, stress doubles


how is toughness of a material defined

AREA under the stress vs strain curvearea under the curve represent the total energy absorbed during the loading process


forces acting on bone

axial--parallel to long axis--made up of tensile (lengthen) and compressive (shorten) forcessheartorsional bending (4 types)


4 types of bending (moments) and the anticipated fracture site associated with them

1. pure bending: apply equal and opposite forces at each end of the bone (uniform bending); fracture can occur anywhere; RARE2. cantilever bending: fixed on one end, and load applied transversely on other end; fracture occurs near site of fixation3. 3 point bending: equal load on both ends and opposite load applied somewhere in the middle; fracture occurs at the site of load application4. 4 point bending: equal load on both ends and 2 opposite loads applied in the middle; fracture occurs btwn two inner loads; RARE


compressive forces on bone result in what type of fracture configuration

OBLIQUE--due to bone being dramatically weaker in shear than compressionwhen loaded in compression, bone fails along the lines of highest shear (usually at 30-45 degrees the to direction of compressive force


tensile forces on the bone result in what type of fracture configuration

TRANSVERSE or perpendicular to the direction of tensile forcerarely occurs as a sole entity


bending forces on bone result in what type of fracture configuration

TRANSVERSE during bending, the side opposite the load (convex) is under tension and under the load (concave) is compressionbc bone is weaker in tension, fracture starts on convex or tension surface


bending and compression forces on the bone result in what type of fracture configuration

COMBINATIONmay start transverse from bending force on tensile side and propagate , split and deviate creating a butterfly fragment


torsional forces on the bone result in what type of fracture configuration



causes of pathologic fractures

1. neoplasia2. osteopenia from immobilization3. osteomyelitis4. iatrogenic bone damage (ie. THR)5. post op implant removalLOW energy fractures--> simple fracture patternsusually at site (stress riser) btwn healthy and dz bone


fatigue fractures

repetitive loading causes bone damage at a rate faster than it can be repaireddecreases tensile strength of bone more rapidly than compressive strengthRARE (maybe FCP, avascular necrosis)


fracture gap size and strain associated

small fracture gap HIGH STRAINlarge fracture gap LOW STRAINfor the same amount of instability present


strain necessary for bone formation

LOW strain environment needed for bone formations< 2 % strain


bone healing mechanisms in place to DECREASE strain and aid in bone formation/healing

1. fracture resorption (increasing the denominator)2. callus formation (decreasing the numerator)strain = change in length/original length


types of bone healing

1. primary---contact vs gap2. secondary: inflammatory (hematoma), reparative (angiogenesis; GT), remodeling (Wolffs law; piezoelectric properties)


stages of secondary bone healing

1. inflammatory (hematoma--no stability)2. reparative (angiogenesis; GT--some stability, tolerates high strain to make fibrous connective tissue soft callus) --interfragmentary strain decreases to form fibrous hard callusfibrous hard callus-->cartilage-->(endochondral ossification) mineralization-->woven bone3. remodeling (Wolffs law; piezoelectric takes -->woven bone-->lamellar bone/Haversian system cortical bone under low strain environment)


what are the two physical requirements for primary bone healing to take place

1. interfragmentary strain < 2%2. < 1mm gap


difference btwn contact and gap repair for primary bone healing

Both do not form callus; Both are PRIMARY healing; need stable fracture conditionsBUT contact--direct Haversion remodeling occurs (cutting cones, longitudinal lamellar bone); bone union and remodeling occur in ONE phasegap--two stages: layers of bone laid perpendicular and THEN replaced by longitudinal lamellar bone through Haversian remodeling; bone union and remodeling take place in two stages


concept of distraction osteogenesis

Gavril Ilizarovmechanically induced bone formation via intramembranous ossification1. within gap is fibrous inter zone (radiolucent, central)2. either side of zone = osteoblasts, vascular that deposit osteoid3. with distraction the fibrous inter zone mineralizes


T/FChondroblasts are formed under LOW oxygen tension

TRUEinitial low oxygen tension is a signal for formation of capillary buds and chondroblasts


tension side of femur vs tibia

femur= craniolateraltibia=craniolateral


tension side of humerus

humerus = craniolateral


tension side of radius and ulna

radius= cranialulna = caudal


granulation tissue can withstand ___________% deformation before failure

100% strain


fibrous tissue can withstand ___________% deformation before failure

10-15 % strain


bone can withstand ___________% deformation before failure

2% strain

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