Cornea: Severe Peripheral Corneal Ulceration Flashcards

0
Q

astigmatism

A

what is the main cause of blurred vision in a Mooren ulcer

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1
Q

Mooren ulcer

A

a rare, idiopathic disease characetrized by progressive, circumferential, peripheral, stromal ulceration with later central spread

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2
Q

perforation, scarring

A

severe complications of Mooren ulcer

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3
Q

PUK

A

Mooren ulcer, PUK, or both: typically extends to involve the sclera (scleritis - most important distinguishing feature)

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4
Q

PUK

A

Mooren ulcer, PUK, or both: end-stage may result in contact-lens cornea

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5
Q

PUK

A

Mooren ulcer, PUK, or both: associated with life-threatening systemic disease

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6
Q

both

A

Mooren ulcer, PUK, or both: resection of limbal conjunctiva or cryotherapy may have therapeutic effect

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7
Q

Mooren ulcer

A

Mooren ulcer, PUK, or both: incidence high in areas where helminthic infection in endemic

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8
Q

circumferentially then centripetally

A

pattern of spread of Mooren ulcer

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9
Q

bilateral, rapidly progressive

A

bilateral, rapidly progressive or unilateral, slowly progressive – type of Mooren ulcer in West African males with helminthic infection

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10
Q

unilateral, slowly progressive

A

bilateral, rapidly progressive or unilateral, slowly progressive – type of Mooren ulcer in elderly men and women

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11
Q

true

A

TRUE or FALSE: a Mooren ulcer associated with a systemic condition is by definition PUK

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12
Q

rheumatoid arthritis

A

most common disease association of PUK

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13
Q

peripheral stromal thinning, sclerosing keratitis, keratolysis

A

three variants of PUK in patients with rheumatoid arthritis

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14
Q

PUK

A

Mooren ulcer, PUK, or both: may demonstrate keratolysis in which the central corneal stroma melts acutely

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15
Q

Wegener’s granulomatosis

A

second most common disease association of PUK

16
Q

PUK

A

Mooren ulcer, PUK, or both: may demonstrate minimal inflammation

17
Q

hydration

A

basic treatment of PUK to prevent local action of destructive cytokines

18
Q

conjunctival flap

A

what kind of treatment used for ulceration would be absolutely contraindicated in a case of Mooren ulcer or PUK?

19
Q

both

A

Mooren ulcer, PUK, or both: severe involvement requires use of systemic immunosuppressive agents

20
Q

corticosteroids

A

This treatment for severe peripheral corneal ulceration, though it may suppress inflammation, may actually accellerate melting by delaying re-epithelialization, predisposing to infection, and suppressing collagen production

21
Q

Mooren ulcer

A

Mooren ulcer, PUK, or both: associated with elevated levels of IgA and deficiency of suppressor T cells

22
Q

lamellar

A

if keratoplasty is to be performed in PUK or Mooren ulcer, it should be of this type

23
Q

PUK

A

.

24
Q

Mooren ulcer

A

.