Peptic Ulcer disease Flashcards
1
Q
what is the prevalence of peptic ulcer disease?
A
aprox 10 % incidence (significant prevalence)
2
Q
what is peptic ulcer disease
A
- ulcerative disorder of upper & GI tract
- 20% happens in stomach
- 80% duodenum
3
Q
what layer of intestine does peptic ulcer disease primarily affect
A
-primarily affects mucosa
4
Q
what is the protective factor of the stomach
A
stomach has mucus barrier to protect from HCL
5
Q
what is the protective factor of the duodenum
A
duodenum has pancreatic buffer to protect from, if HCL comes in when no pancreatic buffer (from pancreatic juices) affecting negatively
6
Q
what is the pattern that peptic ulcer disease comes in
A
pattern of remissions & exacerbations
7
Q
what is the etiology of peptic ulcer disease
A
- helicobacter pylori infection (bacterial infection) (not normal bacteria in the gut) : -site
- adhesion
- Urease
