6.1 Immunosuppression and DMARDs Flashcards Preview

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Flashcards in 6.1 Immunosuppression and DMARDs Deck (36)
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31

When do you use Sulphasalazine?

Safe for pregnant people
Good for IBD (Poorly absorbed so stays in the intestines)

32

ADRs for Sulphasalazine

Myelosuppression
Hepatitis
Rash
GI symptoms

33

Advantages of Sulphasalazine?

Safe for pregnancy
Non-carcinogenic
Has very few interactions
Effective
Less Toxic

34

When do you use anti-TNF agents?

If RA is clinically active
If other treatments have failed

35

Why don't you use anti-TNF agents much?

Expensive
Can cause Hypersensitivity
Can cause infections
Hypogammaglobinaemia

36

What is anti-TNF alpha?

Anti-inflammatory
Decreases joint destruction
Decreases angiogenesis