P5 - Fluids and Vascular Disorders Part 3 Flashcards

1
Q

how is blood flow controlled by heart and nervous system (3)

A
  • baroreceptors
  • left atrial volume receptors
  • Osmoreceptors in hypothalamus
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2
Q

role of epinephrine in blood distribution

A
  • acts on B2 receptors -> vasodilation -> increase flow
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3
Q

role of norepinephrine in blood distribution

A
  • acts on A receptors -> vasoconstriction -> reduce flow
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4
Q

vasodilation causes

A
  • hyperemia
  • engorgement of arterioles and capillaries
  • increased metabolic activity
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5
Q

congestion of vessels

A
  • passive engorgement of vascular bed

- decreased outflow

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6
Q

right-sided heart failure causes what kind of congestion

A
  • hepatic
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7
Q

obstruction of venous outflow as a result of (4)

A
  • neoplastic mass
  • inflammatory mass
  • displacement of organ
  • fibrosis resulting from healed injury
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8
Q

nutmeg liver

A
  • alternating tan (normal) and red (congested) areas

- hypoxia in centrilobular areas

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9
Q

left-sided heart failure causes what kind of congestion

A
  • pulmonary
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10
Q

vessel occlusion results in

A
  • acute infarction of dependent tissue
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11
Q

venous infraction due to

A
  • congested intestinal loops that impinge on vessels and veins
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12
Q

pathogenesis after prolonged ischemia

A
  • ATP degraded to adenosine (potent vasodilator to relieve ischemia) -> blood return causes fluid to move into interstitium -> high tissue pressure -> compression of veins (inhibits local blood return) -> blood vessel hemorrhage -> TF released secondary hemostasis and thrombosis
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13
Q

progression of infraction (tan infracts)

A
  • become tan and pale over time as cells swell and tissue becomes necrotic and blood is forced out of infracted area
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14
Q

types of sock (3)

A
  • cardiogenic
  • hypovolemia
  • blood maldistribution
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15
Q

cardiogenic shock

A
  • myocardial infraction
  • dilated or hypertorphic cardiomyopathy
  • outflow obstruction
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16
Q

hypovolemia shock

A
  • low volume due to hemorrhage or fluid loss
17
Q

types of blood maldistribution shock (3)

A
  • anaphylactic
  • neurogenic
  • septic
18
Q

anaphylactic shock

A
  • histamine and other vasoactive mediators released -> vasodilation
  • increased vascular permeability
  • smooth muscle contraction
19
Q

neurogenic shock

A
  • electrochock -> autonomic discharges
20
Q

septic shock

A
  • due to infectious pathogens
21
Q

stages of shock (3)

A
  • nonprogressive
  • progressive (cardiac damage)
  • irreversible
22
Q

clinical signs of chock (6)

A
  • hypotension
  • weak pulse
  • tachycardia
  • hyperventilation with pulmonary rales
  • reduced urine output
  • hypothermia
23
Q

nonprogressive stage of shock

A
  • compensatory mechanisms counter decreased blood volume and peripheral pressure
24
Q

progressive stage of shock

A
  • cardiac damage leads to decreased output, blood pooling and tissue hypoperfusion
25
Q

irreversible stage of shock

A
  • anaerobic metabolism inhibits cellular enzymes for energy production
  • multiorgan failure