P21 - Urinary Part 1 Flashcards
4 main components of the kidney
- glomerulus
- tubules
- interstitium
- vasculature
what part of the kidney should be removed during necropsy to examine the cortical surface
- external fibrous capsule
color of the outer cortex in mature cats
- yellow
when can the glomerulus be seen macroscopically
- when accentuated by inflammation (glomerulonephritis)
- appear as granular foci in cortex on cut surface
type of capillaries the glomerulus contains
- fenestrated
function of mesangial cells in the glomerulus
- production of collage and matrix
- specialized smooth muscle cells that contract tuft
- phagocytosis
- secretion of inflammatory mediators
what are podocytes and what are they important for
- visceral epithelial cells that participate in glomerular filtration
- important for filtration barrier
glomerular filtration barrier filtration slits are formed between what
- podocyte pedicels and fenestrated endothelial cells with shared basal lamina
what is the glomerular basement membrane (GBM) composed of
- type IV collagen and numerous glycoproteins
T/F: the proximal tubule has an absorptive function
- true
T/F: the descending limb is thin and permeable
- true
T/F: the ascending limb is thick and permeable
- false: is thick but is impermeable
interstitial cells are responsible for the production of what
- prostaglandins
amount of connective tissue increases with what 3 things
- age
- chronic inflammation
- ischemic damage
which part of the renal vasculature is more susceptible to embolism leading to renal infarction (2)
- interlobular arteries
- arcuate artery
