P13 - Neoplasia

Question 1

hyperplasia

Answer 1

• increase in cellular numbers

Question 2

is hyperplasia reversible

Answer 2

• yes

Question 3

epithelial cells ability to undergo hyperplasia

Answer 3

• quick to respond to stimuli for proliferation

Question 4

smooth muscle, bone and cartilage ability to undergo hyperplasia

Answer 4

• intermediate ability to proliferate

Question 5

striated muscle, nervous system ability to undergo hyperplasia

Answer 5

• negligible

Question 6

physiologic causes of hyperplasia

Answer 6

• endometrial and mammary gland epithelial cells to hormones

Question 7

compensatory causes of hyperplasia

Answer 7

• damage to one part of an organ
• wound healing
• goiter

Question 8

goiter

Answer 8

• thyroid gland undergo hyperplasia in response to iodine deficiency

Question 9

pathologic causes of hyperplasia

Answer 9

• persistent stimulation

- can be precursor to neoplastic transformation

Question 10

idiopathic causes of hyperplasia

Answer 10

• nodular hyperplasia rather common in certain organs such as liver, pancreas or spleen

Question 11

metaplasia

Answer 11

• transformation of one differentiated cell type to another

Question 12

dysplasia

Answer 12

• abnormal pattern of tissue growth, often with disorderly arrangement of cells and cell atypia

Question 13

dysplasia is often due to

Answer 13

• persistent, severe injury/irritation

Question 14

anaplasia

Answer 14

• loss of cellular differentiation

Question 15

primitive cellular morphology

Answer 15

• variation in size and shape
• nuclear variability
• prominent and hyperchromic nucleoli
• mitotic figures

Question 16

is anaplasia reversible

Answer 16

• no, it is irreversible and considered malignant