P14 - Neoplasia Part 2 Flashcards

1
Q

pre-neoplastic changes preceding neoplasia (4)

A
  • hypertrophy
  • hyperplasia
  • metaplasia
  • dysplasia
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2
Q

neoplasia (5)

A
  • new growth
  • tumor
  • can be benign or malignant
  • irreversible
  • loss of responsiveness to normal growth/death controls
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3
Q

growth limits for benign

A
  • limited
  • circumscribed
  • encapsulated
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4
Q

growth limits for malignant

A
  • unrestricted
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5
Q

mode of growth for benign

A
  • expansion

- pedunculation

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6
Q

mode of growth for malignant

A
  • expansive

- infiltrative

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7
Q

metastasis of benign

A
  • none
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8
Q

metastasis of malignant

A
  • frequent
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9
Q

recurrence of benign

A
  • rare
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10
Q

recurrence of malignant

A
  • frequent
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11
Q

anaplasia of benign

A
  • well differentiated
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12
Q

anaplasia of malignant

A
  • anaplastic (poorly differentiated)
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13
Q

tissue structure of benign

A
  • nearly normal
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14
Q

tissue structure of malignant

A
  • abnormal
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15
Q

stroma of benign

A
  • usually abundant
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16
Q

stroma of malignant

A
  • usually scanty
17
Q

mitotic figures of benign

A
  • few
18
Q

mitotic figures of malignant

A
  • numerous
19
Q

blood supply of benign

A
  • usually adequate
20
Q

blood supply of malignant

A
  • adequate
21
Q

tissue destruction of benign

A
  • minimal
22
Q

tissue destruction of malignant

A
  • frequent
23
Q

cellular size of benign

A
  • uniform
24
Q

cellular size of malignant

A
  • pleomorphic
25
Q

growth rate exceptions to general rule

A
  • papillomas (benign)

- hormone dependent mammary tumors

26
Q

benign non-glandular end in

A
  • “oma”
27
Q

benign glandular end in

A
  • “adenoma”
28
Q

malignant non-glandular end in

A
  • “carcinoma”
29
Q

malignant glandular end in

A
  • “adenocarcinoma”
30
Q

mesenchymal tumors are generally cells from

A
  • connective tissue, muscle, blood cells, endothelial and related cells
  • generally spindle cells in streams/bundles
31
Q

teratomas

A
  • tumor composed of multiple neoplastic tissues foreign to part which they arise
  • usually benign
32
Q

mixed tumor

A
  • arise from cells that are normally found in the tissue in which they arise
  • can be benign or malignant