6.8.16 Flashcards

(31 cards)

1
Q

Turner synd: renal ssx

A
  • horseshoe kidney
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Turner synd: lymph ssx

A
  • lymphedema

- cystic hygroma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Turner synd: cardiac ssx

A
  • bicuspid aortic valve

- aortic coarctation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Turner synd: gyn ssx

A
  • streak ovaries
  • 1ary amenorrhea
  • infertile
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Turner Synd: physical appearance

A
  • short stature
  • web neck
  • shield chest
  • low post hairline
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

neural tube defect: prenatal dx

A

AFP & ACE in amniotic fluid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

chronic renal allograft rejection: ssx

A
  • worsening HTN

- slow progressive rise in serum Cr

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

chronic renal allograft rejection: renal bx findings

A
  • obliterative fibrous intimal thickening
  • tubular atrophy
  • interstitial fibrosis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

post triangle of neck: which N vulnerable to injury?

A

spinal access N (CN XI)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

injure spinal access N: affect which muscle?

A

trapezius

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

weak trapezius: ssx

A
  • shoulder droop
  • impaired abduction of arm above horizontal
  • winging of scapula
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

drugs w high hepatic clearance tend to have what property?

A

high lipophilic ==> & high vol of dist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

geriatric pt: drugs to avoid

A
  • antichol –> ie 1st gen antihist
  • a-blocker
  • TCA
  • sulfonylurea
  • sedating pain meds
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what stimulates insulin release?

A

increased ATP production in pancreatic beta cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

maturity-onset diabetes of the young: cause

A

glucokinase mutation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Case: central vasc catheter + TPN + yeast in blood –> what infection?

17
Q

femoral N injury: ssx

A
  • weak quadriceps
  • loss of patellar reflex
  • loss of sensation: ant/med thigh, medial leg
18
Q

femoral N: runs along what muscle?

19
Q

what indicates severe mitral regurg?

A

S3 –> high regurg vol, LV vol overload

20
Q

what produces S3?

A

tensing of chordae tendinae during rapid filling & expansion of ventricle

21
Q

what is: metab by 1st order kinetics

A

constant fraction of drug eliminated per unit time

22
Q

drug –> continuous infusion –> metab by 1st order kinetics: how long to reach steady state?

A

4-5 half lives

23
Q

which histone is outside the histone core?

24
Q

RA: typical findings

A

PIP & MCP: bilat pain, stiff, deformity

25
what is: rheumatoid factor
IgM autoAb to Fc portion of IgG
26
rheumatoid factor: indicates
marker of tissue damage & dz activity
27
anaerobic glycolysis: how regenerate NAD+?
NADH transfer electrons to pyruvate to form lactate
28
why is it important to regenerate NAD+ in glycolysis?
G3P deH: glyceraldehyde-3-phosphate (G3P) --> 1-3-bisphosphoglycerate (BPG) Cells have limited amts of NAD+ --> need for above run --> if use up NAD+ without regenerating it --> no more glycolysis
29
vitA def: ssx
- night blindness | - hyperkeratosis
30
vitA def: cause
- biliary disorder - exocrine pancreas insuff - intestinal malabsorption
31
skeletal muscle contraction cycle: ATP binding causes?
myosin head to detach from actin filament