Polyarthrite rhumatoïde Flashcards

1
Q

3 cytokines proinflammatoires

A

IL1 IL6 TNF alpha

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2
Q

Radiographies

A

Radiographies bilatérales des mains et poignets de FACE (pas de profil)
pieds de face + 3⁄4 (1ère erosion = 5MT)
RP face + profil (sarcoïdose)
articulations douloureuses

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3
Q

Bilan biologique

A
anti CCP
FR
AAN
BU (amylose AA)
NFS, CRP, BH, créatininémie
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4
Q

2 indications d’arrêt du MTX

A

cytolyse hépatique

pneumopathie d’hypersensibilité

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5
Q

Bilan pré MTX

A
VHB, VHC, VIH
NFS
BH BR
radio P
bHCG
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6
Q

Bilan pré anti TNF a

A
quantiféron ou IDR
NFS
AAN (risque lupus induit)
radio pulm
VHC, VHB, VIH
\+/- bilan hépato rénal
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7
Q

facteurs de mauvais pronostic

A
syndrome inflammatoire intense
positivité FR et ACPA (= anti CCP)
érosions radio
manifestations extra articulaires ou systémiques
HAQ >= 0,5
DAS VS>3,2
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