Chronic Diabetes Flow Chart Flashcards Preview

Physiology Exam 2 Endocrine (Shelby) > Chronic Diabetes Flow Chart > Flashcards

Flashcards in Chronic Diabetes Flow Chart Deck (25)
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1
Q

What happens once ventilation can no longer compensate for metabolic acidosis from increased blood fatty acids and ketosis

A

diabetic coma

severe acidosis = depress brain function

2
Q

What causes dehydration

A

polyurea from osmotic diuresis from glucosuria from hyperglycemia

3
Q

what contributes to the existing hyperglycemia problem NOT from glucose

A

gluconeogensis from blood amino acids from decreased cellular amino acid uptake and increased protein degradation

4
Q

What is the specific cause of the decrease in intracellular glucose

A

decreased glucose uptake by cells

5
Q

low blood volume leads to:

A

low cerebral blood flow

renal failure

6
Q

What is the cause of glucosauria

A

hyperglycemia- proximal tubules cannot keep up with filtration, glucose lost in the urine

7
Q

what causes increased blood fatty acids

A

increased lipolysis

decreased triglyceride synthesis

8
Q

What specifically causes the symptom of polyphagia

A

decreased intracellular glucose

9
Q

increased blood amino acids is a results of

A

decreased cellular amino acid uptake

increased protein degradation

10
Q

insulin deficiency effects on protein

A

decreased cellular amino acid uptake

increased protein degredation

11
Q

Insulin deficiency leads to

(increased/decreased) triglyceride synthesis

(increased/decreased) lipolysis

A

decreased triglyceride synthesis

increased lipolysis

12
Q

What is the cause of polydipsia

A

an attempt to compensate for effects of dehydration

13
Q

metabolic acidosis causes what compensatory mechanism to occur, why?

****it does not always occur tho…

A

increased ventilation

to ventilate CO2 to shift pH up

14
Q

in children, how is proerp growth compromised?

A

increased protein degradation leads to muscle wasting leads to weight loss

15
Q

What causes polyurea

A

osmotic diuresis from glucosuria from hyperglycemia

16
Q

What is the cause of osmotic diuresis

A

glucosauria from hyperglycemia

17
Q

Ketone bodies in the blood do what

A

disrupt blood pH resulting in a metabolic acidosis

18
Q

What is the result of cellular shrinking from dehydration?

A

nerve cell malfunction due to an osmotic shift of water into ECF and the blood

19
Q

How do nerve cells malfunction from cellular shrinking

A

nerve cells lose their ability to maintain correct membrane potentials and form action potentials

20
Q

dehydration leads to what three things:

A

polydypsia

low blood volume

cellular shrinking

21
Q

what causes an increase in gluconeogensis

A

increased blood amino acids

22
Q

What is the cause of ketosis

A

hepatic use of fatty acids from large-scale mobilization of fatty acids from triglyceride stores

23
Q

Hyperglycemia results from what two things

A
  1. inadequate uptake of glucose into cells
  2. increased output of glucose from the liver
24
Q

Why does renal failure occur with low blood volume

A

GFR declines due to inadequate filtration pressure

25
Q

Increased protein degredation leads to

A

muscle wasting

weight loss