Therapeutic Use Of Insulin Flashcards

1
Q

Differences in synthetic insulin

A

Injectable

Loss of portal peripheral gradient

Loss C peptide

Cause weight gain

Not controlled endogenously

Narrow therapeutic index

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2
Q

Two types of insulin

A

Rapid acting

Long acting insulin

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3
Q

Molecular size of insulin correlates with

A

Absorption from subcutaneous injection sites

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4
Q

Modify insulin toro what?

A

Make it faster acting or longer lasting

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5
Q

Standard conc of insulin

A

100 units per ml (called U100)

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6
Q

Basal boils insulin regimen

A

Basal: long acting insulin twice or once daily

+

Prandial: rapid acting analogues before meals

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7
Q

Measure insulin when

A

Before meals and before bed

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8
Q

Insulin dose adjustment golden rules

A

Look for hypos first

Look for a pattern

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9
Q

DAFNE IS

A

Teach type 1 people about how to manage their insulin

5 day programme

Emphasis on building confidence and appropriate independence

Taught how to adjust insulin to life style

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10
Q

Insulin pump therapy is

A

Continuous subcutaneous insulin infusion all day

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11
Q

How are type 2 people given insulin?

A

Basal ( long acting) given pre bed

Measured pre breakfast

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12
Q

If you cahange conc of premixed insulin you must

A

Also change conc of the other insulin in the premix

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13
Q

Type 1 therapy

A

Basal boils

Insulin pump

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14
Q

Type 2 therapy

A

Bedtime insulin
Twice daily mixed

Basal bolus

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15
Q

Side effects of insulin

A

Hypoglycaemia
Weight gain

Very rarely allergies

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