Anti-Cytokine

Question 1

Ustekinumab blocks IL _____ and IL _____ while Secukinumab, Ixekziumab, and Brosalumab block IL-_____A to treat Psoriasis

Answer 1

12, 23, 17

Question 2

IL-1 and IL-6 are blocked by Anakinra and Tocilizumab and are both used to treat _____ _____

Answer 2

Rheumatoid Arthritis

Question 3

The co-stimulatory molecule on the T-cell is known as CD_____

Answer 3

28

Question 4

______ , Such as Leflunomide or Methotrexate, prevent the proliferation of lymphocytes. For example, can block T-cells talking with B-cells or B-cells from making Antibodies.

Answer 4

Disease Modifying Anti-Rheumatic Drugs (DMARDS)

Question 5

Etanercept, Infliximab, Adalimumab, and Certolizumab all block _____ and are used to treat Rheumatoid Arthritis as well as Crohn’s

Answer 5

TNF-A

Question 6

Mnemonic for Lupus treatment with Pathway blockage

Answer 6

Big Ass Fat Fucks have Big Beli’s and hunt Wolves (BAFF is blocked by Belimumab)

Question 7

Belimumab blocks ______ to neutralize B-cell proliferation and to treat _____

Answer 7

BAFF, Lupus

Question 8

ABATACEPT uses _____ to block _____ Cells through the ______ receptor

Answer 8

CTLA-4, T-, Co-Stimulatory