Antihistamines

Question 1

In regards to the respiratory system, the H1 receptors cause broncho_____

Answer 1

Constriction

Question 2

Cetirizine, Loratadine, and Fexofenadine are all ____ Generation H1 Antihistamines

Answer 2

Second

Question 3

The H1 receptor vasodilates via _____ production

Answer 3

NO

Question 4

Levocetirizine and desloratadine are ____ generation H1 antihistamines, which means they are activated forms of previous generation

Answer 4

Thrid

Question 5

All the immuno hematopoietic cells contain H____ Histamine receptors

Answer 5

4

Question 6

Cimetidine and Ranitidine are are _____ Antihistamines that can inhibit CYP450 enzymes

Answer 6

H2

Question 7

H1 receptors are found on the _____ muscle as well as postsynaptic brain neurons; and use G_____ signaling to work with IP3 and DAG

Answer 7

Smooth, Q

Question 8

“Birds love grains” What are the two main Degranulation inhibitors?

Answer 8

1. Cromolyn

2. Nedocromil

Question 9

The Urticarial response to stinging insects/plants uses the _____ Histamine Receptor

Answer 9

H1

Question 10

Cimetidine, Ranitidine, Famotidine, and Nizatidine are all _____ Antihistamines

Answer 10

H2

Question 11

Both H3 and H4 receptors use G____ signaling

Answer 11

i

Question 12

______ Generation Antihistamine drugs are:

• Neutral
• Hydrophobic
• Enter CNS
• Short-acting

Answer 12

First

Question 13

The H2 receptor vasodilates via _____ production

Answer 13

cAMP

Question 14

_____ Generation Antihistamine drugs are:

• Ionized
• Hydrophilic
• No CNS
• Long-acting

Answer 14

Second

Question 15

Seeing the “Amine” or “z” in the drug means its _____ antihistamine

Answer 15

H1

Question 16

Seeing the “Tid” in the drug name means it’s a _____ antihistamine

Answer 16

H2

Question 17

H2 receptors are found in the _____ Mucosa, cand cardiac muscle; with G____ signaling

Answer 17

Gastric, S