Cytokines Flashcards

Dr. Langer

1
Q

IL-8 Function:

A

Chemotaxis

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2
Q

Blocking CXCR4 and CCR5 can help treat _____

A

HIV

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3
Q

The chemokine receptors CXCR____ and CCR____ are needed for infection

A

4, 5

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4
Q

The Dominant receptor for HIV is the ____ protein on T-cells

A

CD4

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5
Q

IFNAR-1 and IFNAR-2 are:

A

Receptors for Type I IFN

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6
Q

Type I and Type II cytokine receptors use _____-_____ Signaling

A

Jak-Stat

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7
Q

High levels of IL-1 and TNF can cause _____

A

DIC

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8
Q

Low levels of IL-1 and TNF promotes _____

A

Inflammation

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