Transplantation Immunology

Question 1

HLA Haplotypes A,B,C refer to Class _____ MHC molecules

Answer 1

I

Question 2

In the direct pathway for Transplant rejection, the Key affector cells are _____ and they mainly target the epithelium after being presented to Antigen from the graft.

Answer 2

CD8 T-Cells

Question 3

HL Haplotypes DP, DQ, DR, refer to Class _____ MHC Molecules

Answer 3

II

Question 4

Hyperacute Rejection from Transplants is driven by pre-formed _____, within minutes to hours; surgeon will see organ become mottled and non-functional as well as Fibrin Thrombi.

Answer 4

antibodies

Question 5

In antibody-mediated rejection, you see inflammation focused in the _____

Answer 5

Vessels

Question 6

In the indirect pathway for Transplant rejection, the Key affector cells are ________ and ______ that mainly target the blood vessels

Answer 6

CD4 T-cells, B-Lymphocytes

Question 7

In Chronic Kidney transplant rejection, you’ll start to see the organ-specialized structures such as the Glom. Caps become _______ as well as the _____ in the interstitium

Answer 7

Thicken, Fibrosis

Question 8

In the acute pathway for Transplant rejection, the Key Affector Cells are activated _______

Answer 8

Macrophages