8/27/12 Flashcards Preview

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Flashcards in 8/27/12 Deck (13):
1

What tumor marker should be monitored in pts w/ liver cirrhosis and at risk for hepatocellular carcinoma?

Alpha-fetoprotein

2

CA-125 is a tumor marker elevated in 80% of people with _______.

ovarian cancer

3

Are the ACh receptors at the neuromuscular junction muscarinic or nicotinic? Ionotropic or metabotropic?

Nicotinic, ionotropic

4

Pt. w/ Marfanoid habitus, numerous flesh-colored nodules around the oral mucosa, and suspected medullary carcinoma of the thyhroid. Dx?

MEN 2B (Syndrome also includes pheochromocytoma.)

5

What are the characteristics of MEN 1 syndrome?

"diamond"; 3 P's:
Pituitary tumor (prolactin or GH)
Parathyroid tumors
Pancreatic (gastrin, VIP, insulin, glucagon)

6

What are the characteristics of MEN 2A?

"square"; 2 P's:
Parathyroids
Pheochromocytoma
Medullary carcinoma of the thyroid (parafollicular cells)

7

What are the characteristics of MEN 2B?

"triangle"; 1 P:
Pheochromocytoma
Oral/intestinal ganglioneuromas
Medullary carc. of the thyroid
(Marfanoid habitus)

8

Name the hemorrhagic skin lesions in increasing order of size.

petechia, purpura, ecchymosis

9

What is the size of a purpuric lesion?

5mm - 1 cm

10

How does Protein A, found on the surface of S. aureus, prevent opsonization?

binds Fc portion of IgG

11

IgA protease is a virulence factor seen in some strains of _______.

Strep. pneumoniae

12

How do you differentiate Aspergillus from Rhizopus or Mucor in the nasal cavity of an immunosuppressed pt?

Aspergillus - V-shaped (45 deg) branching
Mucor/Rhizopus/Absidia - right angles

13

Black necrotic eschar in nasal mucosa of pt. who had DKA. Tx?

surgical debridement and amphotericin B