9/7/12 pt. III Flashcards Preview

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Flashcards in 9/7/12 pt. III Deck (24):
1

Does the trachea deviate toward or away from the affected lung in a large pleural effusion?`

away

2

Does the trachea deviate toward or away from the affected lung in atelectasis?

toward

3

Name 2 drugs that can cause seizures.

Bupoprione
Isoniazid
Imipenem

4

Pick's disease affects what area of the brain?

frontal cortex

5

Where in the cell is transketolase found? What pathway is it involved with?

cytoplasm; pentose phosphate

6

What is the defective protein in hypertrophic cardiomyopathy?

beta-myosin heavy chain, a cardiac sarcomere protein

7

Injury to what blood vessel is likely to occur in fracture of the neck of the femur and may cause avascular necrosis?

medial circumflex a.

8

Wilson's disease causes cystic degeneration of what area of the brain?

putamen

9

Where can you see the caudate nucleus in a coronal section of the cortex?

lateral to ventricles, supero-medial to internal capsule

10

What is the most common manifestation of CMV infection in the immunocompetent adult?

mono

11

What is the most common manifestation of CMV infection in an HIV pt?

retinitis

12

Which TB drug works best intracellularly?

pyrazinamide

13

Nevirapine, efavirenz, and delavirdine are all ...

non-nucleoside reverse transcriptase inhibitors (NNRTIs)

14

Dofetilide, which may be used for pharmacological cardioversion, is what kind of anti-arrhythmic?

Class III - slows K+ rectifier current

15

What is pituitary apoplexy?

hemorrhage into a pre-existing pituitary adenoma

16

How does the tetrodotoxin block the action potential?

binds closed Na+ channels, preventing depolarization

17

peptostreptococcus and fusobacterium may be found where in the normal adult?

oral flora

18

What is chlorpheniramine?

first gen H1 receptor antagonist (like diphenhydramine)

19

What do jistological specimens of HAV infected livers look like?

ballooning degeneration of hepatocytes, mononuclear infiltrates, and Councilman bodies (eosinophilic, apoptotic hepatocytes)

20

Middle-aged male w/ chronic GI upset, greasy stools, weight loss, joint pain, and PAS+ macrophage infiltrate in lamina propria of intestine. Dx?

Tropheryma whippelii

21

Amphotericin B and Nystatin inhibit fungal growth by?

binding ergosterol in cell membrane

22

What system converts pro-carcinogens to carcinogens?

CYP450

23

What two organ systems does Kaposi's sarcoma affect?

Skin and GI

24

What cardiac pathology causes an S4?

decreased LV wall compliance