8. Selective serotonin and/or norepinephrine reuptake inhibitors. Flashcards Preview

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Flashcards in 8. Selective serotonin and/or norepinephrine reuptake inhibitors. Deck (8)
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1

Selective serotonin reuptake inhibitors (SSRI)

first line of action antidepressants
take 1 to 2 months to achieve maximal effect

drugs...
Fluoxetine
Paroxetine
Sertraline
Citalopram

2

Selective serotonin & norepinephrine reuptake inhibitors (SSNRI)

for patients not responding to SSRIs and chronic painful symptoms
take 1 to 2 months to achieve maximal effect

drugs...
Duloxetine
Milnacipran
Levomilnacipran

3

Selective norepinephrine reuptake inhibitors (SNRI)

Reboxetine
Atomoxetine

4

Fluoxetine

should be discontinued for 6 weeks before MAOI treatment is initiated
for bulimia nervosa
lowest risk for discontinuation syndrome
long half-life

5

Paroxetine & Sertraline

short acting
discontinuation syndrome

6

Duloxetine

Urinary stress incontinence

7

Milnacipran

for patients not responding to SSRIs and chronic painful symptoms
used for fibromyalgia as well

8

discontinuation syndrome

withdrawal syndrome
flu-like symptoms, trouble sleeping, nausea, poor balance, sensory changes, and anxiety