9. Intox Flashcards

1
Q

Metabolito tóxico y dosis tóxica del paracetamol

A

NAPQ1 (necrosis hepatocel)
Dosis 200 mg/kg
Dosis supraterapéutica 90 mg/kg/d

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2
Q

Antídoto paracetamol

A

N-acetil-cisteína 140 mg/kg/dosis
Lavado gástrico
Carbón activado máx 100 g

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3
Q

Clínica y lab paracetamol

A

↑Enzimas hepáticas, INR
4 etapas
*Anorexia, vóm (24h)
*Sensib Pp y dolor CSD, ↑transaminasas (24-48h)
*Fallo hepático y multiorgánico, fallece o recupera (3-5d)
*Resolución fx hep (4d-2sem)

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4
Q

Dosis tóxica salicilatos

A

Aguda 50 mg/kg
Mod >300
Grave >500

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5
Q

Antídoto salicilatos

A

Carbón activado

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6
Q

Clínica salicilatos

A

GI, acúfenos
Taquipnea, taquicardia, altx edo mental y volemia
Conv, hipertermia

Alcalosis resp → acidosis metab
Coag, CK
Rx: infiltrados pulm difusos

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7
Q

Etiología Sx anticolinérgico

A

Atropina (10 mg), butilhioscina, antihistamínicos

Bloquean acth y M2-M3

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8
Q

Clínica Sx atropínico

A

LOCO como sombrerero
ROJO como betabel
CIEGO como murciélago
CALIENTE como liebre
SECO como hueso

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9
Q

Tx Dx anticolinérgico

A

Lavado gástrico
Carbón activado
Diálisis GI
Benzodiacepinas

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10
Q

Causa Sx colinérgico y serotoninérgico

A

COli: organofosforados
SerotoNI: metoclopramida

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