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Phase 1 > Brick wall model of skin > Flashcards

Brick wall model of skin Flashcards

1
Q

What are the three layers of the skin?

A

Epidermis, dermis, subcutis

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2
Q

What are the five layers of the epidermis?

A

Corneum, lucidum, granulosum, spinosum, basale

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3
Q

How is NMF produced?

A

Profilaggrin-> filaggrin -> NMF

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4
Q

Where is NMF found?

A

In swelled corneocytes

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5
Q

What does NMF do?

A

Moisturize the skin and maintain the acidic environment at the stratum corneum

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6
Q

What is desquamation?

A

When mature corneocytes shed from the surface of the stratum corneum

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7
Q

What connects adjacent corneocytes?

A

Corneodesmosomes

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8
Q

What surrounds the corneocytes?

A

Cornified envolope

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9
Q

What surrounds the cornified envolope?

A

lipid lamellae

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10
Q

What is the role of the lipid lemellae?

A

Keeps water inside the cells, and helps irritants and allergens to bounce off the skin surface

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11
Q

What is the role of the stratum corneum?

A

Barrier to penetrating allergens and irritants, and prevents water loss

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12
Q

What is the role of vitamin D within the skin?

A

Produces anti-microbial peptides for defending skin from bacteria and viruses

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13
Q

What are the 3 signs of inflammation?

A

Red, itchy, dry

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14
Q

What is the cause of red skin?

A

Lymphocyte activity causing dilation of blood vessels

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15
Q

What is the cause of itchy skin?

A

Stimulation of nerves

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16
Q

What is the cause of dry skin?

A

Skin cells leaking, no H2O retention

17
Q

What is the normal skin pH?

A

5.5

18
Q

What do sebaceous glands produce?

A

Sebum

19
Q

What is the term for when products cause acne?

A

Cosmetically induced acne

Phase 1 (41 decks)

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