Microbio - all! Flashcards

0
Q

Osteoperiostitis of the alveoli of the teeth

Secondary to gingivitis

A

Magitot’s disease

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1
Q

Blue pus

By pseudomonas aeruginosa

A

Charrin’s disease

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2
Q

Durand’s disease is caused by

A

Chlamydia trachomatis

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3
Q

Erythrasma is caused by

A

Corynebacterium minutissimum

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4
Q

Tuberculous pericarditis

Cirrhosis of the liver

A

Hutinel’s disease

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5
Q

Hutinel’s disease is caused by

A

Mycobacterium tuberculosis

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6
Q

Lymphocytic choriomeningitis

A

Armstrong’s disease

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7
Q

Tyzzer’s disease is caused by

A

Bacillus pilliformis

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8
Q

Chromoblastomycosis

Cauliflower like lesion

A

Chromomycosis

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9
Q

Inflammation of tunica intima of cerebral arteries

A

Heubner’s disease

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10
Q

Self limited diarrhea

Un pasteurized milk and untreated well water

A

Brainered diarrhea

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11
Q

Phycomycosis, mucormycosis

A

Zygomycosis

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12
Q

Epidermodysplasia verruciformis
Red-violet lesions
Tendency to become malignant

A

Lewandowsky lutz disease

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13
Q

Maduramycosis

Madura foot

A

Mycetoma

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14
Q

Infectious ecematoid dermatitis

A

Engman’s disease

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15
Q

Fourth disease

A

Duke’s disease

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16
Q

Echinococcus multilocularis larvae infection

A

Hydatid disease, alveolar

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17
Q

Sepsis of cirrhotic patient

Oyster ingestion

A

Vibrio vulnificus

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18
Q

Chromomycosis is caused by …

A

Phialophora verrucosa, fonsecaea pedrosoi and

Clasposporium carrioni

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19
Q

Prion disease
Mad cow disease
Degenerative brain disorder

A

Bovine spongiform encephalopathy

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20
Q

Rapidly progressive septicemia

Puncture wound from Fish spine

A

Fish-slime disease

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21
Q

Diamond skin disease is caused by…

A

Strep pyogenes

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22
Q

Lethargic encephalitis

A

Economo’s disease

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23
Q

Endartritis obliterans

A

Friedlander’s disease

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24
Q

Vesicles on penis or vagina

A

Durand’s disease

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25
Q

Brown-symmers disease is an acute encephalitis. What are the viral pathogens that causes this?

A
Rabies
Rubella
Mumps
Measles
Influenza
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26
Q

Echinococcus granulosus infection

A

Hydatid disease, unilocular

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27
Q

Acute miliary TB of larynx and pharynx

A

Isambert’s disease

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28
Q

Duke’s disease is caused by…

A

Coxsackie and echovirus

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29
Q

Erysipelothrix insidiosa

Meat and fish handlers

A

Erysepeloid

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30
Q

Osteochondritic separation of epiphyses due to syphilis

A

Wegner’s disease

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31
Q

Transmission of armstrong’s disease

A

Food or dust contaminated by rodents

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32
Q

Rheumatic endocarditis

Delayed sequel for pharyngeal infection by group B strep

A

Boulilauds disease

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33
Q

Engman’s disease is caused by

A

Staph

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34
Q

Mycetoma is caused by

A

Allescheria boydii or actinomycetales

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35
Q

Polymorphous skin eruption

Etiology unknown

A

Habermann’s disease

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36
Q

Congenital syphilis

By treponema pallidum

A

Duboi’s disease

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37
Q

Superficial bacterial skin infection

A

Erythrasma

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38
Q

Syphylitic disease of the bursa

By treponema pallidum

A

Verneuil’s disease

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39
Q

Liver and intestine necrosis

Contact with rodents or dogs

A

Tyzzer’s disease

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40
Q

Armstrongs’s disease is caused by

A

Lymphocytic choriomeningitis virus LCM of arena virus

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41
Q

Swine erysipelas

Acute febrile vascular disease

A

Diamond-skin disease

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42
Q

Economo’s disease is caused by

A

Neurotropic virus

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43
Q

Diseases caused by coxsackie B3 and B5

A

Devil’s eye
Myocarditis and pericarditis
Pleurodynia (Bornholm’s disease)

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44
Q

Rimantadine and amantadine action

A

Prevents viral un coating in influenza A

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45
Q

CMV infection recurrence in immunocompromised patients, especially AIDS patient.

A

CMV retinitis

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46
Q

Re activation to zoster from…

A

Dorsal root ganglia

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47
Q

Incubation period of chickenpox

A

10-21 days

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48
Q

Glycoprotein the breaks down neuraminic acid, an important component of mucin

A

NA

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49
Q

Prion disease

A

Kuru
Gerstmann-straussler disease
Prion (13-3-3 protein)

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50
Q

Positive sense RNA virus

A
PCCRaFT 
Picornavirus 
Calicivirus 
Coronavirus
Reovirus
Flavivirus
Togavirus
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51
Q

Most common viral encephalitis in the Philippines

A

Japanese encephalitis

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52
Q

Negative sense RNA viruses

A
"Always Bring Polymerase Or Fail Replication"
Arenavirus
Bunyavirus
Paramyxovirus 
Orthomyxovirus
Filovirus
Rhabdovirus
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53
Q

Diagnosis for parvovirus

A

PCR

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54
Q

Primary infection of HSV 1

A

Gingivostomatitis - painful group of vesicles on the lips and mouth, which ulcerate and has usually without leaving a scar. Often accompanied by fever and viral symptoms

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55
Q

Family of hepa D virus

A

Deltavirus

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56
Q

Type of RNA virus which are like mRNA, they are immediately translated by the host’s ribosome into protein

A

Positive sense RNA virus

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57
Q

Diagnostic preparation in isolating HSV

A

Tzanck smear, cowdry A

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58
Q

Coxsackie A or B:

In mice, it causes paralysis and death with multiple organ damage

A

Coxsackie B

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59
Q

Diseases caused by poliovirus

A

Mild flu-like illness
Nonparalytic poliomyelitis: Aseptic meningitis
Paralytic poliomyelitis

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60
Q

Hepatitis that is chronic, cirrhosis, carcinoma and carrier

A

Hepatitis C

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61
Q

Protein found in paramyxovirus that results in multinucleated giant cells (called syncytial cells)

A

F protein

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62
Q

Non defective parvovirus strain

A

B19 virus

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63
Q

Reoviruses

A

Respiratory, Enteric, Orphan

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64
Q

Transfusion hepatitis

A

Hepatitis C

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65
Q

Kluver-bucy syndrome

A

Herpes encephalitis

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66
Q

Polio virus initially replicated in the tonsils and Peyer’s patches, spreading to the blood, and across cns barrier to the (anterior,posterior) horn of the spinal cord.

A

Anterior horn cells

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67
Q

Intact virus of hepatitis B

A

Dane particle

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68
Q

Hepatitis that may cause hepatocellular carcinoma

A

Hepatitis B and C

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69
Q

All RNA virus are SIngle stranded, except…

A

Rotavirus

Reovirus

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70
Q

Disease caused by parvovirus which ensues when the virus stops the production of RBCs in the bone marrow

A

Transient aplastic anemia crisis

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71
Q

Transmission of poliovirus

A

Fecal-oral transmission

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72
Q

Rhinovirus is acid-labile or acid-stable?

A

Acid-labile

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73
Q

Also known as break bone fever

A

Dengue fever

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74
Q

Treatment for CMV infection

A

Ganciclovir

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75
Q

Caliciviruses

A

Norwalk virus

Hepatitis E

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76
Q

Type of RNA virus that is transcribed in reverse fashion into DNA

A

Retrovirus

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77
Q

Most common cause of common cold

A

Rhinovirus

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78
Q

Papovavirus
Polyomavirus that causes mild and ASYMPTOMATIC infection in children. Also seen from immunosuppressive kidney transplant patients and HPV.

A

BK polyomavirus

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79
Q

RNA virus has this enzyme for synthesis.

A

RNA-dependent RNA polymerase

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80
Q

Building block of capsid

A

Capsomer

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81
Q

Herpesvirus that cause infectious mononucleosis

A

EBV

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82
Q

RNA viruses that cause gastroenteritis

A

Rotavirus (reovirus)

Calicivirus

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83
Q

Causes adult acute t-cell leukemia and tropical spastic paraparesis (partial paralysis of lower limb)

A

Human T lymphotrophic virus type 1 (HTLV-1)

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84
Q

Retrovirus has this required enzyme for synthesis

A

Reverse transcriptase

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85
Q

Virus that cause common cold and has prominent halo and spikes

A

Coronavirus

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86
Q

TORCHES can cross blood-placental barrier

A
Toxoplasmosis
Rubella
CMV
Herpes, HIV
Syphilis
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87
Q

Most frequent cause of viral (aseptic) meningitis

A

Mumps virus
Coxsackie
Echovirus

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88
Q

Intranuclear inclusion bodies seen in yellow fever virus infection

A

Councilman bodies - acidophilic inclusion

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89
Q

Most important antigen of EBV

A

Viral capsid antigen (VCA)

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90
Q

Diseases caused by HSV 1

A

Gingivostomatitis
Encephalitis
Keratoconjunctivitis
Herpes labialis

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91
Q

Largest virus

A

Poxvirus

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92
Q

Poxvirus that is Completely eradicated worldwide

A

Variola virus

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93
Q

Type of RNA virus which should be transcribed first into positive sense RNA virus.

A

Negative sense RNA virus

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94
Q

Bronchiolitis

A

RSV

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95
Q

Infectious RNA

Hamstring Myalgia

A

Poliovirus

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96
Q

Influenza B and C infects…

A

Human only

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97
Q

HPV genes implicated in carcinogenesis

A

E6, E7 genes

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98
Q

Non paralytic polio

A

Aseptic meningitis

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99
Q

Australian antigen

A

Hepatitis B

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100
Q

True or false : genetic material of viruses may be both DNA and RNA.

A

False. Never both

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101
Q

Intranuclear inclusion bodies seen in poliovirus infection

A

Cowdry B

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102
Q

Aka slow virus

A

Lentivirus

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103
Q

Only occurs in inflenza A because of trading of RNA segments between animals and human strains. It is a reassortment, a major changes of the HA and NA resulting in devastating influenza pandemics.

A

Antigenic shift

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104
Q

Difference between Orthomyxovirus and paramyxovirus

A

Combined HA and NA Glycoprotein (wherein in Orthomyxovirus they are separate)
Has fusion protein (F protein)

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105
Q

Treatment for poliovirus

A

Pleconaril - inhibits penetration
Salk vaccine - formalin-killed poliovirus injected subQ
Sabin vaccine (OPV) - attenuated polio virus is ingested

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106
Q

Small mutations resulting in minor changes in the antigenicity of NA or HA. This results in epidemics go the common flu.

A

Antigenic drift

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107
Q

HSV 8 transmission

A

Sexually transmitted especially in homosexual men

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108
Q

Influenza A infects..

A

Human and animals

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109
Q

physical separation of the viral nucleic acid from the outer structural components of the virion so that it can function.

A

Uncoating

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110
Q

Disease caused by b19 virus of parvovirus with characteristic “slapped cheek” rash.

A

Erythema infectiosum

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111
Q

Diseases caused by poxvirus

A

Smallpox

Molluscum contagiosum - small white bumps with central dimple (like wart). Often found in genital region.

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112
Q

Gamma group herpesvirus

A

EBV, HSV-8

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113
Q

Catarrhal

A

Measles virus

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114
Q

Recurrence of VZV leads to what disease?

A

Shingles - painful eruption of vesicles isolated in a single dermatome. The vesicles dry up and form crusts which disappears in about 3wks.

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115
Q

All DNA virus have linear DNA, except…

A

Papovavirus

Hepadnavirus

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116
Q

Entire infectious unit

A

Virion

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117
Q

Steps of viral replication

A
  1. Adsorption and penetration
  2. Uncoating
  3. Synthesis and assembly of viral products
  4. Release of virions from host cell (by lysis or by budding)
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118
Q

Most common viral cause of infant pneumonia

A

RSV

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119
Q

T or F: acute viral hepatitis never becomes chronic in hepatitis A

A

True

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120
Q

All RNA virus are enveloped, except…

A

PCR
Picornavirus
Calicivirus
Reovirus

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121
Q

Characteristic appearance of the vesicle rash in chickenpox

A

Dew drop lesion on the top of a rose petal

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122
Q

Herpesvirus causes this type of infection where in the virus migrates up to the nerves to sensory ganglia and reside there. It will be activated in peripheral skin

A

Latency

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123
Q

Focal micro glial nodules in rabies

A

Babes nodules

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124
Q

Arenaviruses

A

Lymphocytic choriomeningitis virus (LCM)

Lassa virus

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125
Q

Arthropod borne viruses (arbovirus)

A

Togavirus
Flavivirus
Bunyavirus

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126
Q

Dengue fever is a biphasic fever. What is its vector

A

Aedes mosquitoes

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127
Q

T or F: IFN does not protect virus-infected cell and not itself the antiviral agent

A

True

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128
Q

Forscheimer spots

A

Rubella virus

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129
Q

All DNA virus have icosahedral capsid, except…

A

Pox virus

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130
Q

Family of hepa G virus

A

Flavivirus

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131
Q

Enteric hepatitis C

A

Hepatitis E

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132
Q

Family of hepa C virus

A

Flavivirus

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133
Q

Type I or viral IFN

A

IFN alpha and beta

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134
Q

Most common poliomyelitis

A

Abortive poliomyelitis

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135
Q

Rhinovirus replicates better in what temperature

A

33 degrees centigrade

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136
Q

Steps in viral pathogenesis

A
  1. Viral entry
  2. Primary viral replication
  3. Viral spread
  4. Cellular injury
  5. Host immune responses
  6. Viral clearance
  7. Viral shedding
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137
Q

Papovavirus
Polyomavirus that causes Progressive multifocal leukoencephalopathy (PML) characterized by degenerative cns white matter disease

A

JC polyomavirus

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138
Q

Varicella is highly contagious. It causes what disease?

A

Chickenpox

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139
Q

DNA virus which is circular and ds. The complete strand not covalently closed circle and other strand is missing approximately 25% of its length

A

Hepadnavirus

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140
Q

Virulence factor / glycoproteins of Orthomyxovirus

A

Hemagglutinin (HA)

Neuraminidase (NA)

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141
Q

type II or immune interferon

A

IFN Gamma

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142
Q

Papovavirus that causes warts

A

HPV

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143
Q

HPV type that causes verucca vulgaris and condylomata accuminata (hallmark: koilocytes)

A

HPV type 6,11

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144
Q

causes the epidemic keratoconjunctivitis.

A

Adenovirus type 8

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145
Q

Diseases caused by coxsackie A

A

Herpangina - fever, sore throat and small red-based vesicles over the back of the patient’s throat
Hand-foot-and-mouth disease

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146
Q

Family of hepa B virus

A

Hepadnavirus

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147
Q

Most common viral cause of infant diarrhea

A

Rotavirus

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148
Q

Chemical treatment for genital warts

A

Podophyllin

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149
Q

Retroviruses

A

Oncovirus

Lentivirus

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150
Q

Diagnostic tests for EBV

A

Paul-bundle test
Heterophil antibody test (positive by 2wks of illness)
Monospot test

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151
Q

Infectious particles composed solely of protein with no detectable nucleic acid.

A

Prion

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152
Q

Diseases caused by bunyavirus

A

Encephalitis
Korean hemorrhagic fever
Hantavirus pulmonary syndrome
Muerto canyon virus

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153
Q

Xanthochromic CSF is a finding in …

A

Herpes encephalitis

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154
Q

HSV 6 transmission

A

Transmitted by saliva

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155
Q

Envelope is acquired from

A

Budding

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156
Q

Creutzfieldt-Jakob syndrome
Heidenheim dementia
90% die in 1year
Corneal transplant

A

Prion (13-3-3 protein)

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157
Q

Beta group herpesvirus

A

CMV, HSV-6

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158
Q

HSV 2 latency in …

A

Lumbar or sacral sensory ganglia

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159
Q

Alpha group herpes virus

A

HSV-1
HSV-2
VZV

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160
Q

HPV type that causes common warts

e.g. Verucca plantaris, skin warts

A

HPV type 1, 2, 4 and 7

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161
Q

Appears during early acute phase and disappears before HBcAg is gone

A

Hep B 37 Ag (HBeAg)

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162
Q

Influenza a treatment

A

Amantadine and rimantidine

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163
Q

Picornaviruses

A

Enterovirus: poliovirus, coxsackie A&B, echovirus, hepatitis A
Rhinovirus

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164
Q

Hydrophobia and foaming of mouth in rabies is due to

A

Laryngospasm

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165
Q

Vaccine for poxvirus

A

Vaccinia virus - an avirulent pox virus

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166
Q

Small infectious agents that cause diseases of plants.

A

Viroids

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167
Q

Do not give aspirin in children for fever,. You give what?

A

Acetaminophen

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168
Q

Diseases caused by HSV 2

A

Genital herpes
Neonatal herpes
Aseptic meningitis in neonates

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169
Q

Characteristic appearance in roseola

A

Nagayama spots - in uvopalatoglossal junction

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170
Q

HSV type lesions below the waist

A

HSV 2

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171
Q

All DNA virus are double stranded, except…

A

Parvovirus

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172
Q

Paramyxoviruses

A

Parainfluenza virus
RSV
Mumps virus
Measles virus (rubeola)

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173
Q

Japanese encephalitis vector

A

Culex mosquitoes

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174
Q

RNA virus

A
PCR TCORPR
picornavirus
Calicivirus
Reovirus
Toga virus
Corona virus
Orthomyxovirus
Rhabdovirus
Paramyxovirus
Retrovirus
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175
Q

Mode of transmission of HSV-1

A

Direct contact of mucus membrane

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176
Q

All DNA virus replicates in nucleus, except…

A

Pox virus which replicates in cytoplasm

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177
Q

Hepatitis that enteric and for expectant mother

A

Hepatitis E

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178
Q

Paramyxovirus that has no HA and NA

A

RSV

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179
Q

Family of hepa E virus

A

Calicivirus

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180
Q

HSV 1 latency in …

A

Trigeminal ganglia

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181
Q

Incubation of Hepatitis A

A

14-45 days

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182
Q

Mumps virus has only one antigenic type. Therefore, the MMR vaccine is protective. What is the antigen?

A

“S” soluble antigen

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183
Q

Disease caused by parainfluenza virus characterized by strider and barking cough due to infection and swelling of larynx

A

Croup

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184
Q

Mononucleosis is a dse of young adults. As with viral infections, the lower the socioeconomic class, the earlier children are indeed and the milder disease. American teenagers living in high socioeconomic class with better sanitation are infected later in life through social contact such as kissing. Thus the reference to kissing’s disease. What virus causes this?

A

EBV

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185
Q

CMV infection recurrence in immunocompromised patients, especially bone marrow transplant patients

A

CMV pneumonitis

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186
Q

Filovirus that cause mucus membrane bleeding (hemorrhagic fever)

A

Ebola virus

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187
Q

Disease caused by HSV 8

A

Kaposi’s sarcoma
Castleman’s disease (lympho proliferative disorder)
Primary effusion lymphoma

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188
Q

RNA viruses that cause common cold.

A

Coronavirus and rhinovirus (picornavirus)

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189
Q

Herpesviruses has this effect, especially HSV 1&2, and VZV. This results in separation of epithelium and causes blisters.

A

Cytopathic effect - cause cell destruction

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190
Q

Transmission of hepatitis A and E

A

Fecal-oral route

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191
Q

HPV type that causes genital warts

A

HPV type 6,11,16,18

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192
Q

Hepatitis that only carries DNA polymerase within the virion

A

Hepatitis B

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193
Q

RNA virus that contains nonfunctional ribosomes on its surface.

A

Arenavirus

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194
Q

Treatment fro HSV 1&2 and VZV

A

Acyclovir

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195
Q

Smallest virus

A

Picornavirus, parvovirus

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196
Q

Characterized by high fever, black vomitus, jaundice

A

Yellow fever

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197
Q

Family of hepa A virus

A

Picornavirus

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198
Q

Hepatitis that is asymptomatic, alone and acute

A

Hepatitis A

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199
Q

Cannibalism-related prion disease

A

Kuru “shivering”

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200
Q

Coxsackie A or B:

In mice, it causes paralysis and death with extensive skeletal muscle necrosis

A

Coxsackie A

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201
Q

Wheel-shape appearance

A

Rotavirus

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202
Q

DNA virus

A
HHAPPPy , PHP AHP
Parvovirus
Hepadnavirus
Papovavirus
Adenovirus
Herpes virus
Poxvirus
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203
Q

Herpes viruses

A

Herpes simplex virus type 1 and 2 HSV
Varicella-zoster virus VZV
cytomegalovirus CMV
Epstein-Barr virus EBV

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204
Q

Enveloped viruses are heat labile

A

True

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205
Q

Paramyxovirus that only has HA and F protein

A

Measles (rubeola)

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206
Q

Disease caused by HSV 6

A

Roseola infantum (6th disease, exanthem subitum)

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207
Q

All RNA virus have helical capsid symmetry, except…

A
PCRFT, R
Picornavirus 
Calicivirus
Reovirus
Flavivirus
Togavirus 
Rhabdovirus - bullet-shaped
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208
Q

Host cell outcome

A
  1. Death

2. Transformation - oncogene

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209
Q

RNA virus that cannot replicate without hepa B

A

Deltavirus

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210
Q

Disassociation of Dane particles leaves..

A

HBcAg and HBsAg

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211
Q

Eosinophilic intracytoplasmic inclusion in rabies virus

A

Negri bodies

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212
Q

HPV type that causes cervical cancer

A

HPV type 16,18

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213
Q

Antigen found within nuclei of infected hepatocytes

A

HBcAg

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214
Q

Mode of transmission of HSV-2

A

Sexually transmitted

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215
Q

Incubation of hepatitis B

A

50-180 days

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216
Q

Diseases caused by b19 strain of parvovirus

A

Erythema infectiosum

Transient aplastic anemia crisis

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217
Q

Disease caused by influenza virus

A

Flu fever

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218
Q

Transmission of Hepatitis B, C, D

A

Blood transfusion
Needle stick
Sexual
Across placenta

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219
Q

RNA virus that causes rabies

A

Rhabdovirus

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220
Q

Major target cell of EBV

A

B lymphocytes, binding to C3d receptor

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221
Q

HSV type lesions above the waist

A

HSV 1

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222
Q

Recurrent infection of measles after 2 years

A

Subacute sclerosing para encephalitis (SSPE)

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223
Q

What are the papovaviruses?

A

Papillomavirus (HPV)
Polyomavirus
Vacuolating viruses (SV40)

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224
Q

Bunyavirus that is not arbovirus

A

Hantavirus

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225
Q

Filoviruses

A

Ebola virus

Marburg virus

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226
Q

Togavirus that is not arbovirus

A

Rubivirus

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227
Q

DNA virus that causes childhood URTI such as rhinitis, sore throat, fever and conjunctivitis, and the epidemic keratoconjunctivitis (pink eye)

A

Adenovirus

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228
Q

Recurrent infection of HSV 1

A

Herpes labialis (fever blisters,cold sore)

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229
Q

Hematologic hallmark of Monocucleosis

A

Atypical lymphocytes

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230
Q

Autosomal dominant prion disease

Supranuclear gaze palsy

A

Gerstmann- straussler disease

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231
Q

Virus particle that is functionally deficient in some aspect for replication

A

Defective virus

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232
Q

All RNA virus replicates in cytoplasm, except…

A

Retrovirus

Orthomyxovirus

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233
Q

Segmental viruses

A
BORA
bunyavirus
Orthomyxovirus
Reovirus
Arenavirus
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234
Q

Intranuclear inclusion bodies seen in herpes encephalitis

A

Cowdry A

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235
Q

RNA virus that cause rubella (German measles/ 3-day measles)

A

Rubivirus

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236
Q

Vector of yellow fever virus

A

Aedes mosquito

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237
Q

Glycoprotein that binds with sialic acid, often found in the surface of RBC.

A

HA

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238
Q

Vaccine for rubella

A

MMR vaccine
Measles
Mumps
Rubella

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239
Q

Host-coded proteins that are member of cytokines and which inhibits viral replication.

A

Interferon (IFN)

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240
Q

Hepatitis that is defective and dependent to hepatitis B

A

Hepatitis D

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241
Q

Protein coat of viruses

A

Capsid

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242
Q

Diseases caused by flavivirus

A
Yellow fever
Dengue fever
Japanese encephalitis
St. Louis encephalitis
West Nile encephalitis
Hepatitis c
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243
Q

Orthomyxovirus

A

Influenza virus (a,b,c)

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244
Q

Togaviruses

A

Alpha virus:
WEE
VEE
EEE

Rubivirus

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245
Q

Neuraminidase inhibitors that can shorten course of influenza A and B infection

A

Zanamivir (inhaled)

Oseltamivir (oral)

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246
Q

Soluble component of HBcAg and a markers of active disease and highly infectious

A

HBeAg

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247
Q

HPV type that causes laryngeal warts

A

HPV type 6,11

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248
Q

Incubation period of poliovirus

A

7-14 days or 3-35days

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249
Q

Diseases caused by EBV

A

BHINK
Burkitt’s lymphoma: B cell lympho affecting children in central Africa
Hodgkin’s disease : lymphoma characterized by arising in a single node or chain of nodes, spreading in anatomically contagious nodes
Infectious mononucleosis
Nasopharyngeal carcinoma
Kissing’s disease

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250
Q

Phase of viral growth cycle where in soon after interaction with a host cell, the infecting virion is disrupted and its measurable infectivity is lost.

A

Eclipse period

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251
Q

Disease that travels to the cns in a retrograde fashion up to the nerve axon

A

Rhabdovirus

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252
Q

Parvovirus that requires helper virus to replicate

(+) and (-) strand DNA are carried on separate particles

A

Defective parvovirus

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253
Q

Complication of influenza virus infection

A

Secondary bacterial pneumonia in elderly

Reye’s syndrome: children who use aspirin and get liver and brain disease

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254
Q

Hematologic hallmark in CMV

A

Owl’s eye inclusion

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255
Q

Diseases caused by mumps virus

A

Parotitis
Orchitis (in post pubertal male
Meningitis
Encephalitis

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256
Q

T or F: maternal antibody against mumps virus provide protection during 6months of life

A

True

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257
Q

T or F: Icosahedral viruses tend to be stable, losing little infectivity after several hours at 37 °C.

A

True

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258
Q

Incubation of mumps virus

A

18-21 days

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259
Q

The koplik’s spot in measles occur after 1-2days of prodrome. It is small red based blue-white centered lesions in the mouth found specifically in..

A

Opposite the 2nd upper molar

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260
Q

DNA virus that has brick-like appearance

A

Poxvirus

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261
Q

Sandy appearance

A

Arenavirus

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262
Q

Hepatitis that is blood-borne, big, bad, body-fluid

A

Hepatitis B

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263
Q

Typical lesion of staph aureus

A

Abscess

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264
Q

Tetracycline inhibits what ribosomal unit?

A

30s

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265
Q

Growth media which is the source of AA and N (beef,yeast extracts)
An undefined medium because AA source contains variety of cmpds with the exact composition being unknown
Contains all the elements that most bacteria needed for growth and are non selective

A

Nutrient agar

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266
Q

Selective and differential bacterial media:

Thayer-Martin or New York City agar

A

Neisseria with area of normal flora

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267
Q

Selective and differential bacterial media:

Buffered charcoal-yeast extract (BCYE) agar

A

Legionella

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268
Q

Ribosome subunits of fungi, Protozoa, helminths, animals and humans

A

80s

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269
Q

Exotoxins that binds to MHC II receptors

Non specifically activates large number of T cells

A

Superantigen exotoxins

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270
Q

Examples of differential media

A
Blood agar
Eosin methylene blue EMB
MacConkey 
Mannitol salt agar MSA
X-gal plates
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271
Q

Staph that causes UTI in sexually active women

2nd to e.coli

A

Staph saprophyticus

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272
Q

Tears, saliva, and mucus has natural antimicrobial property

This enzyme cleaves the peptidoglycan backbone by breaking GLYCOSYL BOND

A

Lysozyme

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273
Q

Strep pneumoniae is encapsulated thus exhibits what reaction

A

Quellung reaction

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274
Q

Reserve of high energy stored in the form POLYMERIZED METAPHOSPHATE.

A

Volutin granules

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275
Q

(-) peptidoglycan

(+) sterols

A

Eukaryotes

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276
Q

Treatment for strep saprophiticus

A

Quinolones

Trimethoprim-sulfamethoxazole

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277
Q

Enriched media in which nutritionally rich whole blood supplements is the basic nutrient.

A

Blood agar

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278
Q

Disease caused by staph epidermidis

A

IV catheter infections

Endocarditis on normal prosthetic heart valves

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279
Q

Requires living host cells for growth thus they are the only obligatory intracellular organism among bacteria

A

Rickettsia and chlamydia

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280
Q

Enterococci is resistant to vancomycin because of different cross-linking sequence in the cell wall of the bacteria

A

D-ala-lactate

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281
Q

Enzymes of beta hemolytic

A

Streptolysin o and S (hemolysin)

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282
Q

Processes of DNA transfer on bacteria

A

Conjugation, transformation, transduction

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283
Q

The energy for flagellar movement provided by ATP

A

Proton-motive force

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284
Q

Enriched media that contains heat-treated blood (40-45c) which turns brown

A

Chocolate agar

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285
Q

Differential media for lactose fermentation

A

Macconkey

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286
Q

Nutrient agar medium composition

A

Beef extract- 0.3g (mineral and carbo)

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287
Q

A membrane disrupting bacterial exotoxins which contain lecithinase showing a double zone of hemolysis.

A

Cl. Perfringens alpha toxin

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288
Q

Basis of the selective action of several antibiotics

A

Differences in ribosomal RNAs and proteins

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289
Q

Inclusion bodies formed when source of N, S, P are depleted and there is excess C

A

Poly beta hydroxybutyric acid (PHB acid)

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290
Q

Green zone, incomplete hemolysis

A

Alpha hemolytic

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291
Q

Growth at 4C

A

Y. Enterocolitica

L. Monocytogenes

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292
Q

Treatment for staph aureus

A

Prp
Vancomycin (if methicillin or nafcillin resistant)
Clindamycin
Nafcillin or cloxacillin (if beta lactamases resistant)

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293
Q

Backbone of peptidoglycan

A

Alternating n-acetylglucosamine and N-acetylmuramic acid molecules

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294
Q

Transfer of naked forms of DNA which occurs in same sp of bacteria

A

Transformation

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295
Q

Enzyme reaction that produces O2 + H + NADP

A

NADPH oxidase

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296
Q

Capsule of bacillus anthracis is not composed of polysaccharide, it is composed of..

A

Glutamic acid

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297
Q

Linear pcs of DNA

A

Exogenates

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298
Q

Murein or mucopeptide
Structural support and maintains the characteristic shape
Able to withstand media of low osmotic pressure

A

Peptidoglycan

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299
Q

Transport media that uses broth for strict anaerobes

A

Thioglycolate

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300
Q

Type minimal media the contains a single selected agent, usually AA or sugar.
This allows the culturing of specific lines of auxotrophic recombinants

A

Supplementary minimal media

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301
Q

Different types of media for growing different types of cell

A
Differential media
Enriched media
Nutrient media
Transport media
Selective media
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302
Q

Diseases caused by staph aureus (6)

A
Mastitis
Blepharitis 
Cellulitis
Osteomyelitis
Food poisoning
TSS
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303
Q

Spore-forming bacteria

A

Clostridium and bacillus

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304
Q

Flagellum-like structure that provides undulating motion for spirochetes

A

Axial filament

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305
Q

Normal flora of conjunctiva

A

Diptheroids, staph epidermidis and non hemolytic strep

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306
Q

Found in the outer layer of gram positive bacteria
Antigenic, induce ab that are SPECIES-SPECIFIC
mediates the adherence of staph to mucosal cells

A

Teichoic acid

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307
Q

Toxin of vibrio cholerae
Catalyzes ADP-ribosylation of Gs protein ECG activates adenylcyclase that produces high level of cAMP, thus increases water and acid secretion

A

Choleragen

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308
Q

Most common resident of upper respiratory tract

A

Alpha hemolytic strep and neisseria

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309
Q

A selective differential agar used to isolate and identify member of enterococcus

A

Bile esculine agar

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310
Q

Coagulase (-)

A

Staph epidermidis and staph saprophyticus

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311
Q

Selective and differential bacterial media:

Loeffler’s and tellurite medium

A

Corynebacterium diptheria

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312
Q
Growth media used for the growth of only selected microorganisms.
An antibiotic (by which the selective microorganisms is resistant) is added to the medium in order to prevent other cells, which do not posses the resistance, from growing.
A

Selective media

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313
Q

Growth media that contains minimum nutrients possible for colony growth.
Often used to grow wild type microorganism.
Used to select or used against recombinants or exconjugants

A

Minimal media

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314
Q

Selective and differential bacterial media:

TCBS (alkaline medium)

A

Vibrio cholerae

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315
Q

Transport media for vibrio cholera

A

Venkat-ramakrishnan medium

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316
Q

Evasion of immediate host defense:

Listeria

A

Listeriolysin

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317
Q

Components of anthrax toxin

A
Protective Antigen (PA) that serves as B component
Edema factor (EF) that activates adenylcyclase 
Lethal factor (LF) kills cell
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318
Q

Teichoic acid is a polymer of (2)

A

Glycosyl phosphate and ribitol phosphate

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319
Q

Complete cell wall lysozyme digestion

A

Protoplast

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320
Q

Membrane disrupting exotoxins

A

Pore-forming cytolysin

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321
Q

Is cell wall or cell membrane antigenic?

A

Yes

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322
Q

Examples of defined media

A

Nutrient agar medium
Peptone
Agar

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323
Q

Bacteria that grow well in tap and distilled water

A

Psedomonasl

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324
Q

Toxins of staph aureus and its manifestations

A

Enterotoxin: vomiting, watery and nonbloody diarrhea
TSST: asso with tampon use, superantigen
Exfoliatin: phage II staph, scalded skin syndrome, superantigen
Alpha toxin: skin necrosis

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325
Q

Inhibits enolase

A

Fluoride ion

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326
Q

Microaerophilic

A

Campylobacter, helicobacter

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327
Q

Strep pyogenes has what type of capsule

A

Hyluronic acid capsule

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328
Q

Bacteria that escapes macrophage and grow inside them

A
RuMBLeS
Rickettsia
mycobacteria
Brucella
listeria
shigella
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329
Q

Responsible for toxic effects of endotoxins. Found in LPS in OM.

A

Lipid A

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330
Q

Spores can be destroyed this steam heating

A

Autoclaving at 121C for 30 min, psi of 15

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331
Q

Peptone composition

A
  1. 5g protein and N source

0. 5g NaCl as electrolyte

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332
Q

Site of beta-lactamases

A

Periplasmic space

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333
Q

Pore forming cytolysin

A

Alpha toxin by staph aureus

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334
Q

Colonize with further spread

A

Strep. Pneumoniae
Neisseria gonorrheae and meningitidis
H. Influenzae

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335
Q

Mediates the adherence and phage typing in staph aureus

A

Teichoic acid

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336
Q

Examples of nutrient media

A

Blood agar

Chocolate agar

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337
Q

Acid-fast bacteria

A

Mycobacterial

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338
Q

Neurotoxin of Cl. Tetani which act on cns, inhibiting the inhibitory transmitter GABA

A

Tetanospasmin

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339
Q

Transport media that has a non-nutrient soft agar gel containing a reducing agent to prevent oxidation, charcoal to neutralize

A

Stuart transport medium

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340
Q

Transfer of bacterial genes via phage vectors

A

Transduction

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341
Q

Homologous recombination requires what protein

A

Rec A protein

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342
Q

Partial cell wall lysozyme digestion

A

Spheroplast

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343
Q

Strep pyogene is sensitive to..

A

Bacitracin

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344
Q

(+) peptidoglycan

(-) sterols

A

Prokaryotes

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345
Q

Neurotoxin of Cl. Botulinum that acts on peripheral synapses, blocking the release of neurotransmitters

A

Botulinum toxin

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346
Q

Selective and differential bacterial media:

EMB or MacConkey

A

Enteric bacteria

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347
Q

Hemolytic activity of strep pneumoniae

A

Alpha hemolytic

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348
Q

Obligate anaerobes

A

Actinomyces
Bacteroides
Clostridium

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349
Q

Enzyme reaction that produces H2O + O2

A

Catalase

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350
Q

Bacterium that is an obligate parasite

A

Treponema PALLIDUM

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351
Q

(-) teichoic acid; endotoxins

A

Gram negative bacteria

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352
Q

Test in lancefield classification

A

Precipitin test

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353
Q

Selective and differential bacterial media:

Chocolate agar

A

Haemophilus and neisseria for sterile area

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354
Q

Involved in cross-linking

A

D-alanine

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355
Q

Superantigen exotoxins examples

A

Toxic shock syndrome toxin (TSST) by staph aureus

Strep pyogenes exotoxin A (SPE-A)

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356
Q

In what phase in bacterial growth cycle when there is nutrient depletion or toxic products slow down growth until the number of new cells produced balances the cells that die
(Living=death)

A

Stationary phase

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357
Q

Minimal media contains

A

Carbon source (succinate)
Salts (Mg, N, P)
Water

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358
Q

(+) teichoic acid; exotoxin

A

Gram positive

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359
Q

Bacteria reproduce by this process in which one parent cell divides to form 2 progeny cells

A

Binary fission

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360
Q

Bacteria that has thick peptidoglycan

A

Gram (+) bacteria

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361
Q

In what phase in bacterial growth cycle when there is a marked decline on the number of viable bacteria.

A

Death phase

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362
Q

They have chitin, which is a polymer of N-acetylglucosamine

A

Fungi

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363
Q

A-B toxin that inhibits protein synthesis (5)

A
Diptheria toxin
Exotoxin A
Shigella toxin
Shigalike toxin 
Verotoxin
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364
Q

Differential media mannitol fermentation

A

Mannitol salt agar

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365
Q

Gelatinous layer covering the entire bacterium

Composed of polysaccharide

A

Capsule

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366
Q

No hemolysis

A

Gamma hemolytic

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367
Q

Differential media that is used in strep test, contains bovine heart blood that becomes transparent in the presence of hemolytic streptococcus

A

Blood agar

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368
Q

Evasion of immediate host defense:

Mycoplasma

A

Ciliastasis

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369
Q

It a liquid or gel designed to support the growth of microorganisms or cells.

A

Growth medium or culture medium

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370
Q

Staph epidermidis is the normal flora of…

A

Skin ans mucus membrane

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371
Q

Selective and differential bacterial media:

Regan-Lowe

A

Bordetella pertussis

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372
Q

Evasion of immediate host defense:

Mycobacterium tuberculosis

A

Sulfolipids (sulfatides)

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373
Q

A single circular molecule of loosely organized DNA lacking a nuclear membrane and mitotic apparatus

A

Nucleiod

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374
Q

Obligate aerobes

A

Pseudomonas

Mycobacteirum

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375
Q

Component of exotoxin that binds to specific cell surface receptors and initiates internalization of the A component. It determines what cell type each toxin damages.

A

B component

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376
Q

What is the type of sex pili used for bacterial conjugation

A

Type VII

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377
Q

Treatment for staph epidermidis

A

Vancomycin

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378
Q

Produce igA protease

A

N. gonorrheae and meningitidis

H. Influenzae type B

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379
Q

Spores contains their own DNA

What structure Coats the spores?

A

Dipicolinic acid (calcium chelator)

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380
Q

Toxin of enterotoxic e.coli

Internalize A component to ADP-ribosylates Gs, which activates an adenylcyclase that produces high level of cAMP

A

Labile toxin

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381
Q

Strep pneumonia does not live in the presence of…

A

bile and optochin

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382
Q

Oxygen generates 2 toxic molecules

A

Hydrogen peroxide

Superoxide radicals

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383
Q

(+) sterols

Smallest bacteria

A

Mycoplasma

Mycoplasma genitalium (468 genes)

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384
Q

Bacteria infected by virus

A

Bacteriophage

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385
Q

Obligate intracellular pathogens

A

Mycobacterium leprae
Chlamydia
Mycoplasma

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386
Q

Peptidoglycan synthesis is inhibited by..

A

Penicillin and cephalosporin

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387
Q

Functions as the origin of the transverse septum that divides the cell on half and as the binding site of DNA bacterial ribosomes

A

Mesosome

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388
Q

Cross linking enzyme on the surface of bacteria which is targeted by beta-lactam antibiotics

A

Transpeptidase

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389
Q

Growth media that distinguishes one microorganism type to another.
This uses biochemical characteristics of the microorganism growing in the presence of specific nutrients or indicators

A

Differential or indicator media

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390
Q

Selective and differential bacterial media:

Hektoen enteric agar

A

Salmonella and shigella spa

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391
Q

One of the ways to visualize capsules, where it swells in the presence of homologous antibodies

A

Quellung reaction

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392
Q

A polysaccharide coating secreted by many bacteria

Adhere to various structures such as on the surface of teeth by strep.mutans

A

Glycocalyx or slime layer

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393
Q

Examples of transport media

A

Thioglycolate
Stuart transport medium
Venkat-ramakrishnan medium

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394
Q

They are determined by its rigid cell walls

A

Bacterial shape

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395
Q

Strep pyogenes causes what disease.

A

Pharyngitis

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396
Q

Replicate only within cells
Inner core of either DNA or RNA but no cytoplasm
Depends on host cells for protein synthesis and energy generation
Fast mutation

A

Virus

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397
Q

A-B toxin that inhibits protein synthesis:

Diptheria toxin

A

EF-2 inhibitor

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398
Q

Catalase (+)
Coagulase (+) forms golden yellow colonies
Mannitol (+)

A

Staph aureus

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399
Q

Component of exotoxin which internalize and inhibits a specific critical intracellular function causing damage to the cell. It is the active toxic portion of toxin

A

A component

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400
Q

Bacteria that invades the Peyer’s patches thru the phagocytic M cells

A

Shigella

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401
Q

Colonize with toxin elaboration

A

Corynebacterium diptheriae

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402
Q

Differential media for lac Operon mutants

A

X-gal plates

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403
Q

Mycobacteria is an acid fast bacteria, resisting decolorization with an acid alcohol after being stained by carbolfuchsin.
What component contributes to this property?

A

Mycolic acid

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404
Q

Exchange of two nearly identical pcs of DNA

A

Homologous recombination

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405
Q

Occurs when nutrients (c and n) are depleted

A

Sporulation

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406
Q

Staph aureus is a normal flora of..

A

Nose

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407
Q

Criteria of transport media (5)

A

1) temporary storage of specimens
2) maintains specimen’s viability without altering their conc
3) contains buffers and salt only
4) lacks C, N and other GF so as to prevent microbial multiplication
5) in isolating anaerobes, must be free from molecular oxygen

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408
Q

Lancet shape diplococci

A

Strep pneumoniae

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409
Q

Selective and differential bacterial media:

Lowenstein Jensen

A

Mycobacterium tuberculosis

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410
Q

Transfer of DNA directly from one living bacterium to another.
Bacterial sex.
Major mechanism for transfer of antibiotic resistance.

A

Conjugation

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411
Q

Most common bacterial resident of large intestine

A

Bacteroides

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412
Q

Contains gene for toxins and antibiotic resistance

A

Plasmid

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413
Q

Prokaryotes, especially bacteria doesn’t have true nucleus, rather they have..

A

NUCLEOID

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414
Q

Staph epidermidis is ____ sensitive

A

Novobiocin

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415
Q

Enzyme reaction that produces ClO + H2O

A

Myeloperoxidase

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416
Q

Determined group of beta hemolytic strep

A

C carbo

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417
Q

4 phases of bacterial growth cycle

A

1) lag phase
2) log phase
3) stationary phase
4) death phase

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418
Q

Functions of capsule

A

Virulence
Identification
Adherence
Antigen in vaccine

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419
Q

A-B toxin that inhibits protein synthesis:

Shiga toxin

A

Of shigella dysenteriae type I

A component cleaves 60s ribosomes

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420
Q

In what phase in bacterial growth cycle occurs a vigorous metabolic activity where cells do not divide yet.

A

Lag phase

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421
Q

In what phase in bacterial growth cycle when there is rapid cell division

A

Log phase

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422
Q

Major determinant of growth of bacteria

A

Nutrients

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423
Q

D-ala-D-ala is targeted by what antibiotic?

A

Vancomycin

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424
Q

Highly resistant structures formed in response to adverse conditions

A

Spores

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425
Q

Bacteria that grows in amoeba in streams

A

Legionella

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426
Q

Clear zone, complete hemolysis

A

Beta hemolytic

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427
Q

Axial filament.
Counterclockwise rotation - ?
Clockwise rotation -?

A

Counterclockwise rotation - directed motion

Clockwise rotation - tumbling

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428
Q

Undefined medium (aka basal or complex medium) contains: (3)

A
  1. C source
  2. Water
  3. Various salts
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429
Q

Invagination of cytoplasmic membrane

A

Mesosome

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430
Q

A-B toxin that increase cAMP

A

Labile toxin
Anthrax toxin
Pertussis toxin
Choleragen

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431
Q

Differential media for lactose and sucrose fermentation

A

EMB

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432
Q

Toxin that inhibits Gi which is the negative regulator of adenylcyclase thru ADP ribosylation thus increasing cAMP

A

Pertussis toxin

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433
Q

Enzyme reaction that produces H2O2 + O2

A

Superoxide dismutase

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434
Q

Determined by orientation and degree of attachment of bacteria at the time of cell division

A

Bacterial arrangement

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435
Q

True or false: pathologic effects of endotoxins are similar irrespective of organism

A

True

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436
Q

transport enzyme and oxidative phosphorylation

A

Plasma membrane

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437
Q

Ribosome subunit of bacteria

A

70s (50s and 30s)

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438
Q

A-B toxin that inhibits protein synthesis:

Verotoxin

A

Of e.coli serotype O157:H7
Inactivates protein synthesis by removing adenine from the 28s rRNA
Causes bloody diarrhea

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439
Q

Most important virulence factor of streps

Provides type specific immunity

A

M protein

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440
Q

Growth media commonly used to harvest as many different types of microbes as are present in the specimen.
Contains nutrients required to support the growth of wide variety of organisms.

A

Nutrient media

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441
Q

Erythromycin inhibits what ribosomal subunit of bacteria?

A

Inhibits 50s

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442
Q

Evasion of immediate host defense:

N. gonorrheae

A

Capsule

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443
Q

Agar composition

A

1.5g solidifying agent
100ml distilled water
pH 7

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444
Q

Breaks down the beta 1->4 bonds between NAM and NAG

A

Lysozyme

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445
Q

Group a strep

A

Strep pyogenes

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446
Q

Cytokines that cause fever

A

TNF, IL-1, IL-6

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447
Q

Facultative anaerobes

A

Strep

E. coli

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448
Q

Strep pneumoniae produces this enzyme causing mucosal colonization

A

IgA protease

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449
Q

Single, covalently closed circle or a loop of double stranded DNA

A

Bacterial chromosome

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450
Q

Defined medium (aka chemically defined medium or synthetic medium) contains:

A
  1. All chemical used are known

2. No yeast, animal or plant tissue present

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451
Q

Major protein in the cell wall of staph aureus which binds to Fc portion of IgG

A

Protein A

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452
Q
Evasion of immediate host defense:
Some gram (-)
A

Membrane activation (MAC) resistance

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453
Q

Entamoeba, trichomonas

A

Diamond medium

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454
Q

Cryptosporidium

A

Sheather’s sugar flotation

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455
Q

Microsporidia

A

Ryan’s trichrome blue stain

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456
Q

Trichinosis

A

Bemtonite floccukation test

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457
Q

Schistosoma

A

Kato’s thick smear method

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458
Q

Acanthamoeba

A

Culbertson’s medium

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459
Q

Enterobius, taenia egg

A

Cellophane tape swab

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460
Q

Onchocerca volvulus

A

Mazzotti test

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461
Q

Leishmania

A

Montenegro skin test

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462
Q

Eosinophilia in urine

A

Hansel’s stain

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463
Q

Amoeba

A

Boeck and Orbohlav’s Locke-Egg serum medium

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464
Q

Strongyloides

A

Baermann’s technique
Filter paper strip procedure
Agar plate method

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465
Q

Trypanosoma cruzi

A

Machado-Guerreiro test

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466
Q

Trichomonas

A

Modified thioglycolate medium

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467
Q

Cyclospora

A

KOH

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468
Q

Egg counting

A

Stoll’s technique

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469
Q

Child + peri orbital cellulitis + sinusitis + ear discharge

A

H. Influenzae

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470
Q

Meyers-Kouwenaar syndrome is a synonym for

A

Tropical pulmonary eosiophilia
Occult filariasis
Weingartner’s syndrome

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471
Q

Army barracks + flu like+ maculopapular rash + petechiae

A

Meningococcemia (n.meningitidis)

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472
Q

Toxin of v.cholerae and LT enterotoxic of E. coli are similar

A

B subunits of the toxin bind to GM1 receptors on the host cell

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473
Q

Travel + fever + jaundice + bleeding + neurologic signs

A

Fulminant malaria (p.falciparum)

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474
Q

Diarrhea + beef, poultry + legumes

A

Clostridium perfringens

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475
Q

Watery diarrhea + shellfish ingestion

A

Vibrio cholera

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476
Q

Thumbprint sign + epiglottis

A

H.influenzae

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477
Q

Cellulitis + exposure to fresh water

A

Aeromonas hydrophila

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478
Q

Outbreaks of respiratory infections every winter

A

RSV

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479
Q

Diagnosis of infective endocarditis

A

Duke criteria

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480
Q

Outbreaks of respiratory infections in hospitalized infants

A

RSV

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481
Q

Diarrhea + fried rice ingestion + china town

A

Bacillus cereus

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482
Q

Camping + tick bite + flu like + blanching macules

A

Rocky Mountain spotted fever (rickettsia rickettsii)

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483
Q

Facial or sphenoidal sinus infection + unilateral + retro-orbital headaches

A

Septic cavernous sinus thrombosis (staph)

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484
Q

Pale, greasy, malodorous stools with malabsorption after drinking untreated stream or lake water

A

Giardia lamblia

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485
Q

Aseptic meningitis + facial diplegia

A

Borrelia burgdoferi

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486
Q

Bloody diarrhea + salami + apple juice + raw veggies

A

EHEC

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487
Q

Un pasteurized milk + cabbage

A

Listeria monocytogenes

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488
Q

Indolent + culture negative + a febrile + endocarditis

A

Tropheryma whipplei

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489
Q

HIV + hypoxemia + CXR infiltrates

A

Pneumocystis jiroveci

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490
Q

Para nasal infection + fever + nuchal rigidity + brainstem signs

A

Subdural empyema (microaerophilic staph and strep)

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491
Q

Diarrhea+ ingestion of potato + egg salad + mayonnaise

A

Staph aureus

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492
Q

Major determinant of virulence in h.influenzae

A

Capsule

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493
Q

Painless genital ulcer

A

Primary syphilis

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494
Q

Travel to US (Oklahoma/Arkansas/Missouri) + wild rabbits + tabanid fly

A

Tularemia

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495
Q

Watery diarrhea + salads + cheese

A

ETEC

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496
Q

Hemorrhagic vesicles surrounded by a rim of erythema with central necrosis or ulceration

A

Erythema gangrenosum (p.aeruginosa and A.hydrophila)

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497
Q

Ethmoid or maxillary sinus infection + nuchal rigidity + brain stem signs

A

Septic thrombosis of the superior Sagittal sinus (s.pneumoniae)

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498
Q

“Bull neck” appearance + pseudomembrane

A

Diphtheria

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499
Q

Quinolones kill bacteria by

A

Inhibiting DNA gyrase

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500
Q

Most commons presenting sign of liver abscess

A

Fever

501
Q

19yr old man develops fever, sore throat, malaise, headache, nausea, and rash on the lower parts of both is arms and legs

A

Rickettsia rickettsii

502
Q

Dysentery + mollusks + crustaceans

A

Vibrio parahemolyticus

503
Q

Unilateral/ bilateral parotid swelling + pain aggravate when drinking citrus juice

A

Mumps virus

504
Q

Confers resistance to malaria

A

G6PD, hemoglobin C or E

505
Q

Steeple sign + croup

A

Parainfluenza virus

506
Q

Endocarditis + injection drug users + tricuspid valve

A

Staph aureus

507
Q

Trauma/post-op incision + red, hot, shiny, swollen + exquisite tenderness

A

Necrotizing fasciitis (group A strep)

508
Q

Transplant recipients + diabetes, elderly, Cancer patients + meningismus

A

Bacterial meningitis ( strep.pneumoniae)

509
Q

Ingestion of shellfish + flu like + hypotension + bullous lesions + leg pain

A

Vibrio vulnificus

510
Q

Travel to Europe + tick bite + flu-like + ecchymoses + petechiae

A

Babesia

511
Q

Inflammatory diarrhea + poultry + raw milk

A

Campylobacter jejuni

512
Q

Painful genital ulcers

A

Chancroid

513
Q

Making more than one type of mRNA for the same piece of DNA (virus)

A

Shifting the reading frame

514
Q

Puncture wound of the foot

A

P. aeruginosa

515
Q

Necrotizing fasciitis that leaked into the perineal area causing massive swelling of scrotum of penis

A

Fourneir’s gangrene

516
Q

New properties that a bacterium acquires as a result of expression of the integrated probated genes

A

Lysogenic conversion

517
Q

Involved in the initial viral-specific phosphorylation of acyclovir

A

Thymidine kinase

518
Q

Chemical treatment for genital warts

A

Podophyllin

519
Q

Topical herpes keratitis but no effect on genital lesions

A

Vidarabine

520
Q

Inhibits pox protein synthesis

Blocks translation of late mRNA

A

Methisazone

521
Q

Efavirine inhibits ..

A

CYP2C9 and CYP2C19

522
Q

For treatment-experienced HIV
Effective against HIV strains resistant to other drugs
Induced CYP3A4
Inhibits CYP2C9 and CYP2C19

A

Efavirine

523
Q

Stavudine, zerit, d4T

A

Didehydro-dideoxythymidine

524
Q

Injected intravitreally for treatment of CMV retinitis

A

Fomivirsen

525
Q

NNRTI

A

Delavirdine
Efavirenz
Efavirine
Nevirapine

526
Q

Virazole

A

Ribavirin

527
Q

Prodrug of acyclovir?

A

Valacyclovir.

It has longer duration

528
Q

Has longer half life than amantadine

Require no dosage adjustment in renal failure

A

Rimantadine

529
Q

Ddl, ddc, d4T all cause this adverse effect

A

All Ds cause peripheral neuropathy

530
Q

Mode of action of ganciclovir

A

Inhibits DNA polymerase of cmv and HSV

Chain termination

531
Q

Dihydroxypropoxymethylguanine (DHPG)

A

Gancyclovir

532
Q

Treatment for CMV infection

A

Ganciclovir

533
Q

Do not give aspirin in children for fever,. You give what?

A

Acetaminophen

534
Q

Major route of elimination of acyclovir

A

Renal excretion

535
Q

Highly active anti-retroviral therapy (HAART)

1st line standard care

A

2 NRTI + 1 PI

536
Q

Prodrug and oral prep of ganciclovir

A

Valgancyclovir

537
Q

Host-coded proteins that are member of cytokines and which inhibits viral replication.

A

Interferon (IFN)

538
Q

Has activity against HBV

Asso with fanconi’s syndrome

A

Tenofovir

539
Q

Prophylaxis and treatment for ganciclovir-resistant strains

A

Foscarnet

540
Q

Acyclovir triphosphate inhibits DNA synthesis by (2)

A

Competitive substrate for DNA polymerase

Chain termination

541
Q

type II or immune interferon

A

IFN Gamma

542
Q

Adenine arabinose, ara-A

A

Vidarabine

543
Q

Blood levels decreased by antacids, phenytoin and rifampin
Increased by azole antifungals and macrolides
Teratogenic

A

Delavirdine

544
Q

N-methylisatin - B-thiosemicarbozone

A

Methisazone

545
Q

Adverse effect of ganciclovir

A
MaLTHuS
Mucositis
Leukopenia
Thrombocytopenia
Hepatic dysfunction
Seizure
546
Q

Primary adverse effect of azidothymidine

A

Bm suppression

547
Q

NRTIs

A
Azidothymidine (zidovudine, AZT)
Dideoxyinosine (didanosine, ddI)
Dideoxycytidine (zalcitabine, ddC)
Didehydro-dideoxythymidine (stavudine, d4T)
Ribavirin (Virazole)
Emtricitabine
Methisazone (N-methylisatin B-thiosemocarbazone)
Tenofivir
Lamivudine (3TC)
548
Q

Didanosine, videx, ddl

A

Dideoxyinosine

549
Q

Does not require phosphorylation
Inhibits DNA and RNA polymerase and reverse transcriptase
Pyrophosphate analog

A

Foscarnet

550
Q

NRTI or NNRTI:
Competitive inhibition of HIV-1 reverse transcriptase
Requires intracytoplasmic activation via phosphorylation
Activity against HIV-1 and HIV-2

A

NRTI

551
Q

Thiazole-carboxamide moiety is substituted by aminoimidazole-carboxamide

A

Ribavirin

552
Q

Another guanosine analog that does not cause chain termination

A

Penciclovir

553
Q

Structural difference between nucleoside and nucelotide

A

Nucleotide has an attached phosphate group

It has an ability to persist in cells for long period of time increasing their potency

554
Q

NRTI or NNRTI :
Binds directly to HIV-1 reverse transcriptase resulting in allosteric inhibition of RNA and DNA-dependent DNA polymerase.
Neither competes with nucleoside triphosphate s nor require phosphorylation to be active
No activity against HIV-2

A

NNRTI

555
Q

NNRTI or NRTI
Do not need phosphorylation
Binds directly and incompetitively to reverse transcriptase

A

NNRTI

556
Q

Neuraminidase inhibitors that can shorten course of influenza A and B infection

A

Zanamivir (inhaled)

Oseltamivir (oral)

557
Q

T or F: IFN does not protect virus-infected cell and not itself the antiviral agent

A

True

558
Q

Drug of choice for HSV-1 encephalitis

A

Acyclovir

559
Q

1st protease inhibitor to be approved for treatment of HIV

A

Saquinavir

560
Q

Included in HAART regimen
Effective against HBV infection by inhibiting DNA polymerase
Safely administered to patients with decompensated liver disease

A

Lamivudine (3TC)

561
Q

Antisense oligonucleotide that binds to mRNA of CMV

A

Fomivirsen

562
Q

Trisodium phosphonoformate, foscavir

A

Foscarnet

563
Q

Treatment for AIDS patients resistant to azidothymidine

A

Dideoxyinosine

564
Q

Adverse effects of foscarnet

A

Nephrotoxicity
Hypocalcemia
Hallucination
Seizures

565
Q

Blood level of delavirdine is increased by …

A

Azole, antifungal and macrolides

566
Q

Zidovudine, retrovir, AZT

A

Azidothymidine

567
Q

Rimantadine and amantadine action

A

Prevents viral un coating in influenza A

568
Q

Drug is metabolized to ddCTP to be active

A

Dideoxycytidine

569
Q

Blood level of delavirdine is decreased by

A

Antacids, phenytoin and rifampin

570
Q

Drug of choice for CMV retinitis

A

Gancyclovir

571
Q

Zalcitabine, hivid, ddc

A

Dideoxycytidine

572
Q

1st NNRTI to be approved for treating HIV infection

A

Nevirapine

573
Q

Treatment for advance AIDS patients

A

Didehydro-dideoxythymidine

574
Q

Drug is metabolized into ddATP to be active

A

Dideoxyinosine

575
Q

Other name for rimantadine

A

Flumadine

576
Q

Confers resistance to NRTIs

A

Pol genes

577
Q

Primary adverse effect of dideoxyinosine

A

Pancreatitis

Peripheral neuropathy

578
Q

Phsphorylated acyclovir is converted by thymidine kinase into…. which interferes with viral synthesis by acting as competitive substrate for DNA polymerase and chain termination

A

Acyclovir triphosphate

579
Q

Drugs that inhibits NA synthesis

A
Acyclovir
Ganciclovir
Vidarabine
Fomivirsen 
Foscarnet
580
Q

Inhibits synthesis of guanine nucleotides

For RSV infection in children

A

Ribavirin

581
Q

Treatment fro HSV 1&2 and VZV

A

Acyclovir

582
Q

Has an adverse effect of nightmare and nausea

A

Efavirenz

583
Q

Adverse effect of vidarabine

A
GiPiTCH
Gi irritation
Paresthesia
Tremor
Convulsion 
Hepatic dysfunction
584
Q

NNRTI that penetrates most tissue including CNS and placenta
Metabolized by CYP3A4
Effective in preventing HI vertical transmission

A

Nevirapine

585
Q

Main adverse effect of Didehydro-dideoxythymidine

A

Peripheral neuropathy
Lactose acidosis
Hepatic steatosis

586
Q

Main adverse effect of dideoxycytidine

A

Peripheral neuropathy

587
Q

Nucleoside analog of arabinose, instead of ribose.

Teratogenic.

A

Vidarabine

588
Q

Inhibits early replication of influenza A (not B)

Prevents in coating by binding to M2 (matrix protein)

A

Amantadine

589
Q

NNRTI that are teratogenic

A

Delavirdine

Efavirenz

590
Q

This drug increases the clearance of azidothymidine

A

Rifampin

591
Q

Increase plasma levels of azidothymidine by…

A

Antifungals

592
Q

Inhibitor of protease encoded by HIV

A

Saquinavir

Indanivir

593
Q

Frequent adverse effects of NNRTI

A

Rash (ulceration, SJS)

594
Q

Newest NNRTI

A

Efavirine

595
Q

Resistant strains of influenza A to amantadine

A

H3N2 virus

H1N1 strains

596
Q

Drug of choice for patients with AIDS

A

Azidothymidine

597
Q

Other name for amantadine

A

Alpha-adamantanamine

Symmetrel

598
Q

Contains propylene glycol
Contraindications for pregnancy and young children
Adverse effects of renal or hepatic dysfunction

A

Emtricitabine

599
Q

Enhance bioavailability by fatty foods
Metabolized by cytochrome p450
Teratogenic

A

Efavirenz

600
Q

Ultrahigh-temperature sterilization temp and time

A

140C for 1-3sec

601
Q
Microbial control (reduction and elimination) methods can be classified based upon their level of effectiveness against different types of microbes: 
Treatment include bacterial endospores, which form a 3-layer coat of protection, and acid-fast Mycobacteria which have a waxy cell wall.
A

Highest level of resistance

602
Q

residual chemicals that remain active on surfaces for extended periods of time, providing longer-lasting antimicrobial effects.

A

Chlorhexidine

603
Q

Alcohols are most effective in concentrations ranging from _____.

A

50-90%

604
Q
Peroxides can be used as sterilants (\_\_\_ peroxide vapor), high-level disinfectants (\_\_\_ solutions) or
as antiseptics (\_\_\_ solutions).
A

sterilants (30% peroxide vapor)
high-level disinfectants (25% solutions)
antiseptics (3% solutions).

605
Q

Utilizes steam to penetrate cells, is faster and more effective than dry heat.

A

Moist heat

606
Q

Depending on ______ used, chemicals from these groups (SCHHAAPPP) can be used as sterilants, disinfectants, and antiseptics.

A

Concentration and form (gas, liquid or solid)

607
Q

Autoclave temperature

A

121C for 15 min under 15psi

608
Q

Laundry detergent (benzalkonium chloride)
Dish soap
Household cleaners (409)
Mouthwash. (Cetylpyridinium chloride)

A

Soap and detergents

609
Q

Sorbic, benzoic, propionic, lactic, acetic (vinegar), ascorbic

A

Organic acids

610
Q

Gas or vapor form of a chemical agent (aldehyde, halogen, H2O2)

A

Sterilants

611
Q

Photoreactivation uses visible light (_____nm) to activate repair enzymes (pyrimidine or thymine dimerase or DNA photolyase) that repair the UV damaged DNA.

A

400-750nm

612
Q

Liquid form of chemical agent

A

Disinfectant

613
Q

aromatic compounds that are toxic to tissues in high concentrations. They are intermediate to low-level disinfectants and antiseptics that damage cellular membranes and alter protein structure. They are bactericidal, fungicidal and virucidal, but CANNOT kill ENDOSPORES.

A

Phenol and phenol derivatives

614
Q

Chemical control method that can only eliminate some types of bacteria, fungi and viruses. These agents are generally used to clean materials that contact outer, but not inner, skin surfaces.

A

Low-level disinfectants

615
Q

A powerful, penetrating form of radiation that causes breakages in microbial DNA.

A

Ionizing radiation

616
Q

Microbes that grow best at cooler temperatures ranging from -5°C to 20°Celsius.

A

Psychrophiles and psychrotrophs

617
Q

2% glutaraldehyde solution (cidex)

37% formaldehyde

A

Aldehydes

618
Q
Copper,zinc, mercury and silver
Gold and silver lining of the teeth
Thimerosal (vaccine preservative) 
Silver nitrate eye drops
Zicam
Mercury chlorides
A

Heavy metals

619
Q

Filters pores size used to remove smallest

A

0.01 um

620
Q

Microbes that include bacteria growing in hot springs and deserts, prefer warmer temperatures ranging from 40°C to 80°C.

A

Thermophiles

621
Q

Category of microbial control methods:

Include the use of sterilants, disinfectants, antiseptics and sanitizers

A

Chemical control method

622
Q

process used to disinfect or sterilize gases and heat-sensitive liquids by physically removing microbes. It mechanically traps and removes microbes, but does not kill them and cannot remove some of the toxins they produce. Used to sterilize water, air, blood products, vaccines, drugs, IV fluids, enzymes and media. Surgical masks and respirators filter the air that healthcare workers inhale and exhale.

A

Filtration

623
Q

Danger zone that allows microbes to rapidly grow and metabolize.

A

Temperatures between 20-50C

624
Q

Main advantage of ionizing radiation

A

Ability to penetrate and sterilize material thru outer packages ad wrappings

625
Q

Much lower concentration than sterilants and disinfectants

A

Antiseptics

626
Q

Filters pores size used to remove bacterial cells

A

0.22-0.45 um

627
Q

Batch (historical) pasteurization temp and time

A

63C for 30min

628
Q

process that destroys less than 100 % of microbes on living surfaces. Examples include swabbing skin with iodide prior to surgery and washing your hands with soap.

A

Antisepsis

629
Q

Filters pores size used to remove largest viruses and most bacteria

A

0.22 um

630
Q

A form of non-ionizing energy with a short wavelength (4-400nm). It kills microbes by damaging their DNA.

A

UV radiation

631
Q

Microbes that can be found in geysers and volcanoes, grow best at temperatures above 80°C.

A

Hyperthermophiles

632
Q

Example of microbes that can survive several months in refrigerator.

A

Psychrophiles
Staph aureus
Clostridium

633
Q

Filters pores size used to remove multicellular algae, animals and fungi

A

5 um

634
Q

Lysol, pine-sol, antibacterial soaps and products that contains triclosan

A

Phenol and phenol derivatives

635
Q

Microbicidal/microbistatic:

agents that kill microbes

A

Microbicidal

636
Q

used in cured meats (ham, bacon, hot dogs, bologna, salami) to maintain a bright red color. These substances break down during frying and freezing, causing the meat to lose its “pink” appearance. There has been a link between nitrosamines produced from the cooking of processed meat and cancer in humans.

A

Nitrites and nitrates

637
Q

Chemical control method that can kill fungal spores (sex cells) and acid-fast bacteria (TB), but cannot kill endospores. These agents are typically used to treat materials that come into contact with mucous membranes.

A

Intermediate-level disinfectant

638
Q

can be used to create hypertonic environments, which cause microbial cells to shrink and undergo plasmolysis due to the loss of water. These preservatives are static agents, because they do not kill microbes, they only slow or inhibit their metabolism.

A

Natural preservatives

639
Q

Microbes that include most disease-causing forms of bacteria, grow best at temperatures ranging from 20°C to 40°C.

A

Mesophiles

640
Q

Non-ionizing radiation example

A

Uv radiation

641
Q

any process that removes microbes and other debris or contaminants to “safe levels.” Examples include washing plates and cups.

A

Decontamination

642
Q

It produces highly reactive free radicals that damage proteins and DNA. It is most toxic to anaerobes, which lack the enzyme catalase needed for its breakdown. It is one of the 3 chemical groups that can be used to kill endospores.

A

Hydrogen peroxide s

643
Q

Because dry heat penetrates more slowly than moist heat (steam), dry heat ovens require higher temperatures and longer exposure times in order to effectively sterilize objects.
Dry heat temp and time?

A

1 hour at 171°C or

2 hours at 160°C

644
Q

Disadvantage of UV radiation

A

Unable to penetrate thru substances such as glass, metal and plastic.

645
Q

Iodide (skin antiseptic, betadine surgical scrub)
chlorine gas (sterilant); chlorine bleach (high level disinfectant)
bromine
fluorine (toothpaste and water disinfectant)

A

Halogens

646
Q

Filters pores size used to remove viruses

A

0.01-0.22 um

647
Q

A high pressure chamber that utilizes temperatures of121°C for 15 minutes under 15 psi (pressure) to sterilize nonliving surfaces (kills endospores). Used to sterilize heat-resistant materials, such as glassware, surgical dressings, rubber gloves, metallic instruments, liquids, and some heat-resistant papers and plastics.

A

Autoclave

648
Q
Microbial control (reduction and elimination) methods can be classified based upon their level of effectiveness against different types of microbes: 
Treatment include protozoans in both cyst and vegetative form, Gram-negative bacteria, which have an outer membrane, porins and drugs pumps, as well as fungi, which have a cell wall made of chitin.
A

Intermediate level resistance

649
Q

UV damaged DNA forms ____ that block DNA replication and transcription.

A

pyrimidine (thymine) dimers

650
Q

Process that destroys 100% of microbes (even endospores) on non-living surfaces.

A

Sterilization

651
Q

A mechanical method of microbial control used to remove microbes from the surface of instruments and teeth. It utilizes high frequency sound waves to generate “shock waves” that are conducted through living structures or liquids. The force exerted by these shock waves leads to the rupture of microbial membranes and their removal from surfaces. Used to clean surgical instruments, dental instruments, teeth, pacemakers, hearing aids, test tubes and small electronics.

A

Ultrasonic vibration

652
Q

effective physical control agent that can be delivered in both moist (steam sterilization, pasteurization) and dry (bacti-cinerators and ovens) forms.

A

Heat

653
Q

T or F: refrigeration and freezing do NOT kill microbes.

A

True, they merely hold the number of microbes steady (static). Although refrigeration and freezing can slow or halt the growth of most mesophiles, it may allow the slow growth of spoilage bacteria, such as psychrophiles that can grow and metabolize even at freezing temperatures!

654
Q

Filters pores size used to remove Protozoa and small unicellular algae

A

1.2 um

655
Q

Flash pasteurization temp and time

A

72C for 15sec

656
Q

chemicals that alter microbial proteins and at high concentrations and in gas form can be sporicidal

A

Halogens

657
Q

static agents used to prevent food spoilage.

A

Preservatives

658
Q

Chemical antimicrobials range from low-level disinfectants, to intermediate-level disinfectants, to high-level sterilants. Antimicrobial chemicals include:

A

SCHHAAPPP

1) halogens;
2) phenolics;
3) chlorhexidine;
4) alcohols;
5) peroxides;
6) soaps and detergents;
7) heavy metals;
8) aldehydes; and
9) preservatives.

659
Q

Non-ionizing/ionizing radiation:

causes breakage in microbial DNA.

A

Ionizing radiation

660
Q

can be used as low-level disinfectants or antiseptics. They are NOT sporicidal. They oxidize and inactivate proteins and can be toxic to humans

A

Heavy metals

661
Q

Filters pores size used to remove larger viruses and pliable bacteria (mycoplasma, rickettsia, chlamydia, some Spirochetes)

A

0.025 um

662
Q

radiation that can be used to regulate the growth of microbes on non-living substances, such as: food, water, on walls and floors, even the air in dental offices and hospital operating rooms.

A

Non-ionizing radiation (UV radiation)

663
Q

70% ethanol (disinfectants)
50% isopropanol (antiseptics)
Water-free Hand sanitizer such as purell

A

Alcohols

664
Q

Heat helps control microbial growth by…

A

Destroying or denaturing structural and regulatory proteins.

665
Q

Factors that affect the rate at which microbes are killed include:

A

ENARA

1) exposure time to agent (the longer the material is exposed to agent, the more microbes will be killed)
2) number of microbes present on surface (the more microbial contamination, the longer it will take to disinfect it)
3) amt of organic debris or contaminants
4) resistance level of microbes (endospores vs non-endospores);
5) activity level of the agent (cidal versus static).

666
Q

Exposure of human tissue to UV light can result in …

A

UVA (wrinkles)
UVB (sunburn)
UVC (cancer)

667
Q

added to baked goods, cheeses, pickles, sodas, jams, jellies and dried fruits to reduce the growth of mold and bacteria.

A

Organic acids

668
Q

intermediate-level disinfectants or antiseptics that dissolve lipid membranes (surfactants) and denature proteins. They are effective against most fungi and bacterial cells, but CANNOT kill endospore- formers.

A

Alcohols

669
Q

Non-ionizing/ionizing radiation:

uses ultraviolet light to form dimers between neighboring thymines in the DNA.

A

Non-ionizing radiation

670
Q

Sugar and salts

A

Natural preservatives

671
Q

Preferred method for disposing of animal carcasses contaminated with infectious agents.

A

Incineration

672
Q

Chemical control method that are able to kill endospore-forming bacteriaand can be used to completely eliminate all microbes on non-living surfaces. These powerful agents are used to sterilize materials such as catheters, implants, and surgical instruments.

A

High-level disinfectant

673
Q

Filters pores size used to remove yeasts and larger unicellular algae

A

3 um

674
Q

another effective dry heat method, which uses temperatures of 800°C to 6500°C to burn microbial material.

A

Incineration

675
Q

Category of microbial control methods:

Include heat, filtration, UV radiation and US vibration

A

Physical control method

676
Q

Intermediate level disinfectant ___ in killing mycobacteria and non lipid viruses, but does NOT kill endospores

A

Varies

677
Q

Moist heat methods

A

Steam sterilization (Autoclaving, boiling, pasteurization)

678
Q

A low-pressure steam method that requires temperatures of 100°C for a minimum of 10 minutes in order to disinfect, but NOT STERILIZE, objects. Exposing materials to this for 30 minutes will kill most non-spore-forming pathogens, but NOT ENDOSPORES. Used to disinfect drinking water, eating utensils, food, hospital bedding and baby bottles.

A

Boiling

679
Q

Microbicidal/microbistatic:

agents that temporarily inhibit the reproduction of microbes, but do not kill them.

A

Microbistatic

680
Q

T or F:Mechanical agents (filtration) physically remove microbes but do not kill them.

A

True

681
Q

low-level disinfectants used in hospitals, dental offices, and veterinary clinics. They can also be used as skin degerming agents in preoperative scrubs or oral rinsed. It disrupts cellular membranes (surfactants) and denatures proteins, but cannot kill endospores.

A

Chlorhexidine

682
Q

Antimicrobial agents damage microbes by disrupting the:

A

1) cell wall;
2) cell membrane;
3) proteins;
4) NA (DNA or RNA).

683
Q

Used to disinfect drinking water, eating utensils, food, hospital bedding and baby bottles.

A

Boiling

684
Q

Filters pores size used to remove largest bacteria

A

0.45 um

685
Q

Radiation that is Used to regulate the growth of microbes in food, drugs, vaccines, medical plastics, surgical gloves, bone and skin tissue grafts

A

Ionizing radiation

686
Q

An effective sterilizing agent because it can denature structural and regulatory proteins needed for metabolism. Used for water-sensitive materials such as metals, oils, and powders.

A

Dry heat

687
Q

It is cationic quaternary ammonium compounds called “quats.”

A

Soap and detergent

688
Q

prevent the growth of molds in dried fruits, juices, syrups and wines and prevent discoloration of food products.

A

Sulfur compounds (sulfites)

689
Q

A low-pressure, moist heat method used to reduce the number of microbes in MILK and JUICE in order to slow the rate of food spoilage. Milk is not sterile after this, as this techniques kills most microbes that cause human disease and food spoilage, but not all.

A

Pasteurization

690
Q

UV damaged DNa can be repaired by a process called ____.

A

Photoreactivation

691
Q

Ultrahigh-temperature pasteurization temp and time

A

134C for 1sec

692
Q
Microbial control (reduction and elimination) methods can be classified based upon their level of effectiveness against different types of microbes: 
Treatment include naked viruses, Gram-positive bacteria, and enveloped viruses.
A

Low level resistance

693
Q

Used to sterilize heat-resistant materials, such as glassware, surgical dressings, rubber gloves, metallic instruments, liquids, and some heat-resistant papers and plastics.

A

Autoclave

694
Q

Main disadvantage of ionizing radiation

A

Risk of exposure for those who work with this type of radiation.

695
Q

Chemical agents of control have 4 primary sites of action:

A

1) cell wall;
2) cell membrane;
3) proteins;
4) NA (DNA or RNA).

696
Q

weak disinfectants or antiseptics that act as surfactants to disrupt the cellular membranes of some bacteria and fungi. It is unable to kill endospore-forming bacteria.

A

Soap and detergents (quats)

697
Q

Boiling temp and time

A

100C for 10min

698
Q

highly toxic agents which can be used as sterilants, high-level disinfectants, or tissue preservatives depending upon concentration and form (gas, liquid or solid). It inhibits microbial growth by damaging proteins and nucleic acids (DNA and RNA). It can be used to kill endospores and inactivate viruses during vaccine preparation.

A

Aldehydes

699
Q

process that destroys less than 100% of microbes on non-living surfaces. Unable to kill endospores which are the most difficult type of microbe to treat. Examples include applying 5% bleach soln to an operating table and boiling eating utensils after use by sick patients

A

Disinfection

700
Q

organic acids, sulfur compounds,nitrites, and sugars and salts.

A

Preservatives

701
Q

Dry heat methods

A

Incineration (bacti-cinerator)

Sterilization ovens

702
Q

High level disinfectant kills endospores.

A

Some

703
Q

Hibiclens,hibitane, betasept, peridex

A

Chlorhexidine

704
Q

Category of microbial control methods:

Include filtration and US vibration

A

Mechanical control method

705
Q

Ionizing radiation

A

Gamma rays

X-rays

706
Q

Diagnostic test for Enterobius vermicularis infection

A

Scotch tape test on the perianal area

Cellophane tape swab

707
Q

Diagnostic test for Strongyloides

A

Filter paper strip procedure
Agar plate method
Baermann’s technique

708
Q

Lemon-shaped egg

A

Trichuris trichiura

709
Q

Treatment for Strongyloides stercoralis infection

A

Albendazole

710
Q

Pathognomonic sign of taenia solium infection

A

Migrating intraventricular cyst

711
Q

Cephalic cone

Halzoun

A

Fascio hepatica

712
Q

Filariasis is caused by

A

Wuchereria bancrofti

Brugia malayi

713
Q

Lung fluke

A

Paragonimus westermani

714
Q

Intermediate host of loa loa

A

Deer fly

715
Q

“Mal morado” or “erisipelas de la costa”

A

Onchocerca volvulus

716
Q

Fiery serpents that plagued the Israelites by the Red Sea

A

Dracunculus medinensis

717
Q

Resemble gastric carcinoma

A

Anisakis sp.

718
Q

Brood capsules

Liver cysts

A

Echinococcus granulosus

719
Q

Resides in veins surrounding the bladder and deposits egg in urine.
Causes urinary bladder carcinoma
Terminal spine

A

Schistosoma haematobium

720
Q

Sheep liver fluke

Sheep liver rot

A

Fasciola hepatica

721
Q

Transmitted by genus mansonia

A

Brugia malayi

722
Q

Collarette of spine

A

Echinostoma ilocanum

723
Q

Dot sign

A

Ascaris lumbricoides

724
Q

T or F: within the normal human host, there is no immune reaction to living worms

A

True

725
Q

Test for schistosoma cercariae

A

Circum oval precipitin test (COPT)

726
Q

Mode of transmission of fasciolopsis buski

A

Eating aquatic vegetation carrying the cysts

Bamboo shoots and water chestnuts

727
Q

Treatment for onchocerciasis

A

DEC diethylcarbamazine

728
Q

Whipworm

A

Trichuris trichiura

729
Q

Fascio hepatica excysts in..

A

Duodenum

730
Q

Can be acquired thru ingestion of undercooked meat where in the encysted larvae of nematode live in striated muscle

A

Trichinella spiralis

731
Q

Pinworms mature in..

A

Cecum and ascending intestine

732
Q

Box-like segments of tapeworm

A

Proglottids

733
Q

Treatment for filariasis

A

Ivermectin

Diethylcarbamazine DEC

734
Q

Causes neurocysticercosis

A

Taenia solium

735
Q

Treatment for toxocarca canis infection

A

Diethylcarbamazine

736
Q

May cause periorbital edema

A

Trichinella spiralis

737
Q

Bipolar plugs

A

Trichuris trichiura

738
Q

Transmission of fasciola hepatica

A

Eating watercress contaminated with metacercariae

739
Q

African eye worm

A

Loa loa

740
Q

Differentiate in dermal nodule

A

Onchocerca volvulus

741
Q

Hanging groin

A

Onchocerca volvulus

742
Q

Form of larva that can penetrate the skin (n.americanus and s.stercoralis)

A

Filariform larva

743
Q

Infective stage of loa loa

A

Micro filariae

744
Q

Beef tapeworm

A

Taenia saginata

745
Q

Cat/dog hookworm

A

Ancyclostoma braziliensis

746
Q

Barber’s pole

A

Angiostrongylus cantonensis

747
Q

Blood and tissue nematodes spread by ..

A

Bite of arthropod

748
Q

Vector of filariasis

A

Culex, aedes poicilus, and anopheles flavirostis mimimus mosquito

749
Q

Guinea worm

A

Dracunculus medinensis

750
Q

Treatment for Cestodes and Trematodes infection

A

Praziquantel

751
Q

Black river blindness

A

Onchocerca volvulus

752
Q

Infective stage of hymenolepis nana

A

Eggs are directly infectious to humans

753
Q

In trichuris trichiura, there is no auto infection, why is that?

A

Since the eggs must incubate in moist soil for 3-6weeks before they become infective.

754
Q

Treatment for fasciola hepatica

A

Bithionol

755
Q

Blood and tissue nematodes

A

Onchocerca volvulus

Wuchereria bancrofti and brugia malayi

756
Q

Treatment of fasciolopsis buski

A

Praziquantel

757
Q

4 suckers and circle of hooks

A

Taenia solium

758
Q

Acquired when ingested undercooked crabs/crayfish
Ova with operculum
Hemoptysis

A

Paragonimus westermani

759
Q

Dog roundworms

A

Toxocarca canis

760
Q

Positive uterine rosette

Spirometra

A

Diphyllobothrium latum

761
Q

The thickened skin may appear dry, scaly and thick (LEOPARD SKIN)

A

Onchocerca volvulus

762
Q

Infective stage of filariasis in man

A

Microfilariae

763
Q

Intestinal nematodes that are acquired when their larvae penetrate the skin, usually of the foot

A
Necator americanus (hookworm)
Strongyloides stercoralis
764
Q

Intermediate host of Trematodes

A

Snail

765
Q

Vector of onchocerca volvulus

A

Black fly or buffalo gnat

Simulium flies

766
Q

Nematode that causes loeffler’s syndrome -pneumonitis

A

Ascaris lumbricoides

767
Q

Intermediate hosts of diphyllobothrium latum

A

Crustaceans and fish

768
Q

Adult worms of blood and tissue nematodes lives in

A

Lymphatic tissue

769
Q

Reaction to proteins released by dying onchocerca, including fevers, rashes, ocular damage, joint and muscle pain, and lymphangitis as well as hypotension, pyrexia, respiratory distress, and prostration.
Drug reaction to DEC diethylcarbamazine

A

Mazzoti reaction

770
Q

Acquired thru ingestion of raw seafoods

A

Anisakis sp.

771
Q

The most anterior segment of tapeworm, which has suckers or sometimes hook

A

Scolex

772
Q

Garrison fluke

A

Echinostoma ilocanum

773
Q

Length of pork tapeworm

A

2-8meters

774
Q

Dog tapeworm

A

Echinococcus granulosus

775
Q

___proglottids that contains the fertilized eggs

A

Gravid proglottids

776
Q

Pudoc worm

A

Capillaria philippinensis

777
Q

Visceral larva migrans

A

Toxocarca canis

778
Q

Scariest worm

A

Ascaris lumbricoides

779
Q

Causes hydatid disease, an extra-intestinal tapeworm infection

A

Echinococcus granulosus

780
Q

Eating raw fish containing cysts

Causes cardiac beriberi / cardiac failure

A

Heterophyses heterophyses

781
Q

Most common sequela of neurocysticercosis

A

Seizure

782
Q

Rat tapeworm

A

Hymenolepis diminuta

783
Q

Treatment for loa loa infection

A

Ivermectin

Diethylcarbamazine

784
Q

Flatworms

A

Platyhelminthes

785
Q

T or F: flatworms does not have digestive tract

A

True

786
Q

Schistosoma that resides in intestinal tract and deposits eggs in feces.
Small lateral spine.

A

Schistosoma japonicum

787
Q

Diagnostic test in echinococcus granulosus infection

A

Casoni’s skin test

788
Q

“Craw-craw or “sowda”

A

Onchocerca volvulus

789
Q

Cutaneous larva migrans aka creeping eruption (intensely pruritic, migratory skin infection)

A

Ancyclostoma braziliensis

790
Q

Nurse cells

A

Trichinella spiralis

791
Q

Infective stage of dracunculus medinensis to man

A

Microfilariae in Copepods

792
Q

Intermediate host of Echinostoma ilocanum

A

Pila luzonica

793
Q

Cochin china diarrhea

A

Strongyloides stercoralis

794
Q

Schistosoma that resides in intestinal tract and deposits eggs in feces.
Prominent lateral spine

A

Schistosoma mansoni

795
Q

Intestinal nematode that is acquired by ingestion of encysted larvae in muscle (pork meat)

A

Trichinella spiralis

796
Q

Produces large eosinophilic exudates

A

Ascaris lumbricoides

797
Q

Pin worm / seat worm

A

Enterobius vermicularis

798
Q

New world hookworm

A

Necator americanus

799
Q

Mature schistosomal larva that infects human

A

Cercariae

800
Q

Largest intestinal nematode

A

Ascaris lumbricoides

801
Q

Cutting plates

A

Necator americanus

Fasciolopsis buski

802
Q

Blood fluke

A

Schistosoma

803
Q

Occurs when humans take the role of pigs and ingest eggs rather than the encysted larvae

A

Cysticercosis

804
Q

Endemic in Philippines

A

Hymenolepis nana

Echinostoma ilocanum

805
Q

Flukes

A

Trematodes

806
Q

Rat lungworms

A

Angiostrongylus cantonensis

807
Q

A group of Platyhelminthes that is hermaphroditic (has male and female sex organs)

A

Cestodes

808
Q

T or F: all flukes have a water snail species as an intermediate host

A

True

809
Q

Fish tapeworm

A

Diphyllobothrium latum

810
Q

For egg counting

A

Stoll’s technique

811
Q

Has indirect and direct cycle and

Autoinfection where filariform larvae develop and penetrate intestinal wall

A

Strongyloides stercoralis

812
Q

The larvae of diphyllobothrium latum is called..

A

Plerocercoid / sparganum

813
Q

Topical pulmonary eosinophilia

A

Filariasis

814
Q

Tapeworms

A

Cestodes

815
Q

Disease caused by clonorchis sinensis

A

Cholangicarcinoma

816
Q

Max length of diphyllobothrium latum

A

45 meters

817
Q

Diagnostic test for trichinosis

A

Bentonite floccukation test

818
Q

No filariform larvae stage, no tissue invasion, no lung involvement and the eosinophilic count is not elevated

A

Trichuris trichiura

Enterobius vermicularis

819
Q

Schistosoma with Non-operculated ovum

A

Schistosoma japonicum

820
Q

Ova with operculum

Has elongated sucking grooves

A

Diphyllobothrium latum

821
Q

Giant intestinal fluke

A

Fasciolopsis buski

822
Q

Anisakis sp. transmission

A

Acquired thru ingestion of raw seafoods

823
Q

___proglottids that has the male and female sex organs

A

Mature proglottids

824
Q

Has rostellar hooks

A

Taenia solium

825
Q

Causes borborygmi (rumbling and gurgling noise in intestine) and diarrhea

A

Capillaria philippinensis

826
Q

Roundworms

A

Nematodes

827
Q

Causes radiculomyeloencephalitis

A

Angiostrongylus cantonensis

828
Q

Manifests:
Katayama reaction (fever) as a result of the grown adults laying their eggs.
Swimmer’s itch as a result of penetration of cercaria on the swimmer’s skin.
Claystem/pipe stem fibrosis

A

Schistosoma japonicum

829
Q

Causes vitamin b12 deficiency to megaloblastic anemia

A

Diphyllobothrium latum

830
Q

The life cycle of trichuris trichiura is

A

Slow

831
Q

Pork tapeworm

A

Taenia solium

832
Q

Diagnostic test for toxocarca canis

A

Casoni skin test

833
Q

Tramway sign in X-ray

A

Ascaris lumbricoides

834
Q

Causes calabar swelling or fugitive swelling

Crawling across the conjunctiva

A

Loa loa

835
Q

A group of Platyhelminthes that live and mate within digestive tract

A

Cestodes

836
Q

Fluke that is Endemic in Philippines

A

Echinostoma ilocanum

837
Q

Schistosomes

A

S. haematobium
S. japonicum
S. mansoni

838
Q

Tapeworm that is Endemic in Philippines

A

Hymenolepis nana

839
Q

Rectal prolapse

A

Trichuris trichiura

840
Q

Nematodes that has larval form that migrates through the tissue and into the lung at some stage of their life cycle. The larvae grow in the lung, are coughed up and swallowed into the intestine, where they grow into adult worms.

A

Ascaris lumbricoides
Necator americanus
Strongyloides stercoralis

841
Q

Diagnostic test for schistosoma

A

Kato’s thick-smear method

842
Q

Ascaris lumbricoides and Necator americanus have very similar life cycle, they differ only in the path that each larvae form takes to reach the lung:

A

Necator americanus: foot to lung

Ascaris lumbricoides: intestine to lung

843
Q

Filariasis, a wuchereria bancrofti and brugia malayi infection, causes what manifestations?

A

Elephantiasis

Elephantoid fever

844
Q

Treatment for echinococcus granulosus

A

Albendazole

845
Q

Causes Pruritus ani (perianal itching)

A

Enterobius vermicularis

846
Q
Smallest tapeworm (15-55mm) 
Dwarf tapeworm
A

Hymenolepis nana

847
Q

Egg hen shape ova

A

Fasciolopsis buski

848
Q

Infective stage of onchocerca volvulus in man

A

Micro filariae

849
Q

Vector of schistosoma japonicum

A

Onchomelania quadrasi

850
Q

Intestinal nematodes that are acquired thru ingestion of eggs

A
Ascaris lumbricoides 
Trichuris trichiura (whipworm)
Enterobius vermicularis (pinworm)
851
Q

Principal host of Strongyloides stercoralis

A

Man

852
Q

It causes anaphylactic shock when the hydatid cyst bursts

A

Echinococcus granulosus

853
Q

Chinese liver fluke

A

Clonorchis sinensis

854
Q

Toxoplasma is one of the transplacentally acquired TORCHES organisms that can cross bpb. Pregnant women should avoid cats.

A

Just a note

855
Q

Has axonemes

A

Giardia lamblia

856
Q

Plasmodium grows in (liver,Rbc) while reproduce in (liver,Rbc)

A

Plasmodium grows in liver while reproduce in RBC

857
Q

Treatment for toxoplasma gondii infection

A

Pyrimethamine + trisulfapyrimidine

858
Q

Flagellated trophozoite

A

Giardia lamblia

Trichomonas vaginalis

859
Q

Manifestation in visceral leishmaniasis

A

Massive Splenomegaly

860
Q

Trophozoite of this organism asexually bud and divide into 4 merozoites that stick together, forming a cross or x-shaped TETRAD ( MALTESE CROSS)

A

Babesia sp.

861
Q

Intestinal Protozoa that causes bloody diarrhea

A

Entamoeba hystolitica

862
Q

Treatment for pneumocystis jiroveci

A

Trimethoprim-sulfamethoxazole

863
Q

Campers frequently develop this protozoan infection after drinking from clear untreated mountain stream

A

Giardia lamblia

864
Q

Balantidium coli causes

A

Diarrhea

865
Q

Infective stage of plasmodium in man

A

Sporozoites

866
Q

Stain of pneumocystis jiroveci

A

Silver stain

867
Q

Strawberry cervix

A

Trichomonas vaginalis

868
Q

Quartan malaria

A

P.malaria

869
Q

Infective stage of plasmodium in mosquito

A

Gametocyte

870
Q

Blood mucoid stools
(+) tenesmus : Painful spasm of the anal sphincter along with an urgent desire to defecate without the significant production of feces

A

Amebiasis

871
Q

Treatment for chagas disease

A

Nitrofurfurylidine derivative - nifurtimox

872
Q

Giardia lamblia infection often manifests malodorous stool packed with fats.

A

Since giardia lamblia does NOT invade the intestinal walls, there is NO blood in the stool

873
Q

Commonly infects recto-sigmoid large intestine

A

Amebiasis

874
Q

Sausage- shaped gametocyte

A

P.falciparum

875
Q

Ziemann’s stipling

A

P.malariae

876
Q

Villous atrophy - malabsorption

Lactose intolerance

A

Giardia lamblia

877
Q

Positive kerandel’s sign (excruciating pain after minor soft-tissue injury, e.g. in palms and ulnar region.)

A

Trypanosoma brucei rhodesiense

878
Q

Manifestation on acute chagas disease

A

Chagoma - erythematous induration area

879
Q

Vector of leishmania donovani

A

Phlebotomus sandfly

880
Q

Swiss cheese appearance on degeneration

A

Entamoeba hystolitica

881
Q

Vivax and ovale burst loose every..

A

48 hrs (tertian malaria)

882
Q

Diagnostic test for giardia lamblia

A

String test

883
Q

Aestivoautumnal, malignant tertian or sub tertian malaria

Bursts loose irregularly

A

P.falciparum

884
Q

Swimming in freshwater

A

Naegleria fowleri

885
Q

Hypnozoite can only be found in what species of plasmodium

A

P.vivax and ovale

886
Q

Infective stage of entamoeba hystolitica to man

A

Cyst

887
Q

Cryptosporidium parvum, when ingested as a round oocyst contains ___sporozoites

A

4 sporozoites

888
Q

Vector of trypanosoma cruzi

A

Panstrongylus megistus / reduviid bug / kissing bug

Feces

889
Q

Trichomonas that is commensal

A

Trichomonas tenax

890
Q

Falling leaf motility

A

Gardia lamblia

891
Q

Diagnostic test of chagas disease

A

Machado-Guerreiro Test

892
Q

T or F: males can have trichomoniasis

A

True. Usually asymptomatic

893
Q

Malaria life cycle

A
  1. Pe-erythrocytic cycle - from anopheles, sporozoites is injected to human bloodstream to liver. SPOROZOITE becomes TROPOZOITE, then undergoes nuclear division forming SCHIZONTS then cytoplasmic membrane division forming MEROZOITE resulting to liver cell bursting.
  2. Exo-erythrocytic cycle - reinfects liver and repeat cycle
  3. Erythrocytic cycle - enters Rbc (instead of liver cells)
894
Q

Infective stage of leishmania donovani in man

A

Promastigote (flagellated motile form)

895
Q

Manifestation in chronic chagas disease

A

Mega esophagus and mega colon

Chagasic cardiopathy

896
Q

Infective stage of trypanosoma cruzi in man

A

Metacyclic trypomastigote

897
Q

Motility of gardia lamblia

A

Falling leaf motility

898
Q

Most common site of gardia lamblia infection.

A

Upper part of small intestine

899
Q

Hemoflagellate ( lives in the bld stream)
kinetoplast (mass of mito DNA lying close to the nucleus)
Undulating membrane

A

Trypanosoma brucei rhodesiense

Trypanosoma cruzi

900
Q

Treatment for Balantidium coli infection

A

Iodoquinol

901
Q

Merozoite invades all ages of RBC

A

P. Falciparum

902
Q

Algid malaria

A

P.flaciparum

903
Q

Flask-shaped ulcer

A

Entamoeba hystolitica

904
Q

Fungal infection (previously protozoa) common in AIDS

A

Pneumocystis jiroveci

905
Q

Positive Romanas sign (edema lower eyelid with conjunctivitis
Positive intracellular amastigote stage

A

Trypanosoma cruzi

906
Q

Treatment for malaria

A

Chloroquine (vivax, ovale, malariae)
Primaquine (vivax, ovale)
Mefloquine (chloroquine-resistant)

907
Q

Causes tartar teeth

A

Trichomonas tenax

908
Q

East African sleeping sickness

A

Trypanosoma brucei rhodesiense

909
Q

Vector of malaria

A

Anopheles mosquito

910
Q

TETRAD of babesia sp,

A

Maltese cross

911
Q

Vector of trypanosoma brucei rhodesiense

A

Tse tse fly

912
Q

Following ingestion cyst converts back into the motile form, called the…

A

trophozoite

913
Q

When exposed to new environments (such as temperature changes, transit down the intestinal tract, or chemical agents), the protozoa can secrete a protective coat and shrink into a round armored form, called

A

Cyst

914
Q

Culture for trichomonas

A

Modified thioglycolate medium

915
Q

The largest pathogenic Protozoa found in the intestine

A

Balantidium coli

916
Q

Slow granulomatous infection and Meningitis in immunocompromised persons

A

Acanthamoeba

917
Q

Transmission of toxoplasma Gondi

A

Ingestion of infected raw meats or food contaminated with cat feces

918
Q

Treatment for trichomoniasis

A

Metronidazole

919
Q

Protozoa ingests solid pieces of food thru a small mouth called

A

Cytostome

920
Q

Acid fast oocysts

A

Cryptosporidium parvum

921
Q

Diagnostic test for entamoeba and trichomonas

A

Diamond medium

922
Q

P.malaria bursts loose every

A

72 hrs (quartan malaria)

923
Q

Glycogen vacuoles

A

Iodomoeba butschlii

924
Q

Diagnostic test for microsporidium

A

Ryan’s trichrome blue stain

925
Q

Trophozoite and cyst, which is infective?

A

Cysts

926
Q

Plasmodium merozoite invades senescent RBC

A

P.malariae

927
Q

Vector of babesia sp.

A

Ixodes sp.

928
Q

Infective stage of toxoplasma gondii

A

Trophozoite

929
Q

Culture for amoeba

A

Boeck and Drbohlav’s Locke-Egg serum medium

930
Q

The only ciliated protozoan that causes human disease - diarrhea

A

Balantidium coli

931
Q

Diagnostic test for leishmania

A

Montenegro skin test

932
Q

Obligate intracellular parasite (Protozoa)

A

Toxoplasma gondii

933
Q

Culture for acanthamoeba

A

Culbertson’s medium

934
Q

P.vivax and ovale has a dormant form called

A

Hypnozoite

935
Q

Malaria is a febrile disease caused by 4 different Protozoa:

A

Plasmodium vivax
Plasmodium falciparum
Plasmodium ovale
Plasmodium malariae

936
Q

This sensitive diagnostic test is conducted where 40 lab-grown reduviid bugs are allowed to feed on the patient, and 1 month later the bug’s intestinal contents are examined for the parasite.

A

Xenodiagnosis

937
Q

Shepherds crook

A

Chliomastix mesnili

938
Q

Kala-agar (black sickness)

A

Leishmania donovani

939
Q

American trypanosoma

A

Trypanosoma cruzi

940
Q

Common site of infection in amebiasis

A

Recto-sigmoid large intestine

941
Q

Positive ingested Rbc

A

Entamoeba hystolitica

942
Q

Dum dum fever

A

Leishmania donovani

943
Q

Chagas disease

A

Trypanosoma cruzi

944
Q

Blood-borne flagellates

A

Leishmania

Trypanosoma

945
Q

Flagellated protozoan

A

Trichomonas vaginalis

946
Q

Diagnostic test for cyclospora

A

KOH

947
Q

Benign tertian malaria

A

P. vivax (and ovale)

948
Q

Free living meningitis-causing amoeba that lives in freshwater and moist soil.

A

Naegleria fowleri

Acanthamoeba

949
Q

Buffalo-skin or Dyak skin ulcers

A

Entamoeba hystolitica

950
Q

Most common site of cryptosporidiosis

A

Jejunum

951
Q

Incubation period of plasmodium

A

2-4 weeks

952
Q

Causes dysentery, amoebic colitis and liver abscess (anchovy paste)

A

Entamoeba hystolitica

953
Q

Treatment for acute amebic colitis (by Entamoeba hystolitica)

A

Metronidazole

954
Q

Diagnostic test for cryptosporidium

A

Sheather’s sugar flotation

955
Q

Causes paraventricular calcification and encephalomyelitis

A

Toxoplasma gondii

956
Q

Parasites found more commonly in AIDS

A

Pneumocystis jiroveci (MC)
Toxoplasma gondi
Cryptosporidium

957
Q

Winter button sign (posterior lymphadenopathy)

A

Trypanosoma brucei rhodesiense

958
Q

Quotidian fever

A

P.vivax

959
Q

Plasmodium merozoite invades only reticulocyte

A

P.vivax and ovale

960
Q

Clinical form of leishmaniasis caused by L.donovani.

A

Visceral leishmaniasis

961
Q

Rapidly progressing meningoencephalitis in immunocompetent persons

A

Naegleria fowleri

962
Q

Onchocerca volvulus

A

Simulium flies (female black fly)

963
Q

Drancunculus medinensis

A

Copepods (cyclops)

964
Q

Tsutsugamushi

A

Leptotrombidium spp.

965
Q

Babesiosis

A

Ixodes spp

966
Q

Trypanosoma brucei

A

Tse tse fly

967
Q

Borrelia burgdoferi

A

Ixodes tick

968
Q

Bartonella bacilliformis

A

Phlebotomus fly

969
Q

Loa loa

A

Deerfly (mango fly), Chrysops

970
Q

Bartonella Quintana

A

Pediculus humanus

971
Q

Trypanosoma cruzi

A

Panstrongylus megistus (reduviid bug)

972
Q

Schistosoma japonicum

A

Onchomelania quadrasi

973
Q

Rickettsia pox

A

Liponyssoides

974
Q

Rickettsia prowazeki

A

Pediculus humanus

975
Q

Yersinia pestis

A

Xenopsylla cheopis

976
Q

American trypanosomiasis (chagas disease)

A

Triatoma, panstrongylus

977
Q

Rickettsia rickettsii

A

Dermacentor spp

978
Q

Francisella tularensis

A

Dermacentor

979
Q

Echinostoma ilocanum

A

Pila luzonica

980
Q

Borrelia recurrentis

A

Ornithodoros

981
Q

Boutonneuse fever

A

Rhipicephalus

982
Q

Disease cause by strep pyogenes

A
PRAISE 
Pharyngitis
Rheumatic fever
Acute post strep glomerulonephritis  
Impetigo (contagiosa)
Scarlet fever - spares the face
Erysipelas
983
Q

Transmission of L.monocytogenes

A

Ingestion of contaminated raw milk products and cabbages (coleslaw)

984
Q

Produces serpentine colonies

A

Mycobacterium tuberculosis

985
Q

Optochin, bile and quellung positive

A

Strep pneumoniae

986
Q

Long, thin aerobic spirochete that have hook on one or bothe ends, giving them an “ice tongs” appearance

A

Leptospira

987
Q

Clostridium species that is not motile

A

Clostridium perfringens

988
Q

Vector of yersinia pestis

A

Xenopsylla cheopis

989
Q

Between chlamydia and rickettsia, which has fond to columnar epithelium

A

Chlamydia

990
Q

Obligate aerobes

A
NN BBB LMP
neisseria and nocardia
Bacillus cereus, bordetella, brucella
Legionella
Mycobacteria
Pseudomonas
991
Q

Poly microbial

A

Brain abscess

992
Q

Cat-scratch disease
Bacillary angiomatosis
Inoculation lymphoreticulosis
Parinauds occuloglandular syndrome

A

Bartonella henselae

993
Q

Produce medussa head colonies

A

Bacillus anthracis

994
Q

Vector of Borrelia burgdorferi

A

Ixodid nymph tick

995
Q

Causes left-sided valve infection in addicts

A

P. aeruginosa

Candida albicans

996
Q

Number one cause of bacterial bronchitis and and pneumonia in teenagers and young adults

A

Mycoplasma pneumoniae

997
Q

Hematologic hallmark of gardnerella vaginalis infection

A

Clue cells

998
Q

Characteristic fried egg appearance

A

Mycoplasma

999
Q

Yersinia pestis is a gram-neg bacteria that exhibits striking bipolar staining with special stains. What are those?

A

Giemsa or Wayson’s stain

1000
Q

Lucio’s phenomenon

A

mycobacterium leprae

1001
Q

Causes UTI having alkaline urine due to urease

A

Proteus mirabilis

1002
Q

Transmission of coxiella burnetti

A

Inhalation of aerosols

1003
Q

T or F: strep viridans is part of normal oral flora (found in the nasopharynx and gingival crevices) and GIT.

A

True

1004
Q

Treatment for gardnerella vaginalis

A

Metronidazole

1005
Q

Most common cause of duodenal ulcers and chronic gastritis. And second leading cause of gastric ulcers

A

Helicobacter pylori

1006
Q

Job’s syndrome (hyper-IgE syndrome)
Recurrent cellulitis
Spreads from central localized infection.

A

Staph aureus cellulitis

1007
Q

Group B, beta-hemolytic strep

A

Strep agalactiae

1008
Q

Lyme disease

A

Borrelia burgdorferi

1009
Q

Causes bacterial vaginitis

A

Gardnerella vaginalis

1010
Q

T or F: strep agalactiae is part of normal flora of vagina of pregnant women

A

True. About 25% of pregnant

1011
Q

Endemic typhus

A

Rickettsia typhi

1012
Q

Are corynebacterium and listeria catalase positive

A

Yes

1013
Q

Pseudoappendicits syndrome.

A

Yersinia pseudotuberculosis

1014
Q

Yaws

A

Treponema pertenue

1015
Q

Rusty colored sputum in pneumonia

A

Strep pneumoniae

1016
Q

Mycobacterium tuberculosis produces ____ in culture

A

Niacin

1017
Q

Produces black eschar

A

Bacillus anthracis

1018
Q

Corkscrew-shaped spirochete

A

Borrelia

1019
Q

Toxins of staph aureus

A

Exfoliatin
Enterotoxin
TSST-1

1020
Q

“The great pretender”

A

Treponema pallidum

1021
Q
Non fermenters
Hot tub folliculitis (diffuse folliculitis)
Echtyma gangrenosum 
Cellulits ff penetrating trauma 
HAP
A

Pseudomonas aeruginosa

1022
Q

Muscle spasm
Trismus
Risus sardonicus
Respiratory muscle paralysis

A

Tetanus

1023
Q

Lactose fermenter enteric

A

E.coli and klebsiella pneumoniae

1024
Q

Diagnostic test for diphtheria

A

Elek’s test

1025
Q

T or F: salmonella typhi is zoonotic

A

False. S.typhi is not zoonotic and only carried by humans

1026
Q

Growth medium of mycobacterium leprae

A

Footpads of mice or in armadillo

1027
Q

Predictive model for diagnosis of group A strep

A

Centor criteria

1028
Q

Indole negative

Ferments lactose

A

Klebsiella pneumoniae

1029
Q

Red diaper syndrome

A

Serratia mercescens

1030
Q

Causes spontaneous myonecrosis and spontaneous non traumatic gangrene

A

Clostridium septicum

1031
Q

Some people recovering from typhoid fever become chronic carriers, harboring salmonella typhi in their ____ and excreting bacteria constantly.

A

Gall bladder

1032
Q

Swarming enteric

A

Proteus mirabilis

1033
Q

Friedlander’s pneumoniae

A

Klebsiella pneumoniae

1034
Q

Disease that presents with the abrupt onset of a watery diarrhea (classically described as looking like RICE WATER) with loss of up to 1liter of fluid per hr in severe cases.

A

Cholera. It causes death by dehydration

1035
Q

Group A strep, beta-hemolytic

A

Strep pyogenes

1036
Q

Flagella of clostridium has this virulence protein

A

H-antigen

1037
Q

Treatment for yersinia pestis

A

Streptomycin + tetracycline

1038
Q

Most common cause of non-gonoccocal urethritis

A

Chlamydia trachomatis

1039
Q

Causes Rocky Mountain spotted fever

A

Rickettsia rickettsii

1040
Q

Diseases caused by Clostridium septicum

A

Spontaneous myonecrosis

Spontaneous non traumatic gangrene

1041
Q

Cord factor of mycobacteria

A

Trehalose dimycolate

1042
Q

Step agalactiae is hydrolyzed by …

A

Hippurate

1043
Q

Pinta

A

Treponema carateum

1044
Q

Incubation period of Leptospira interrogans

A

5-14 days (2-30days)

1045
Q

Incubation period of yersinia enterocolitica

A

Cold enrichment - 4C For 1wk

1046
Q

Whooping cough

A

Bordetella pertussis

1047
Q

Spirillum minus

A

Rat bite fever

1048
Q

Oroya fever is a profound intravascular hemolytic anemia of a few weeks duration, associated with lesions called VERRUGA PERUANA resembling Kaposi’s sarcoma; also known as Carrión’s disease.

A

Bartonella bacilliformis

1049
Q

Index organism for fecal contamination of water

A

E.coli

1050
Q

Most common bacteria in surface water worldwide

A

Vibrios

1051
Q

Borrelia burgdorferi can invade the brain, cranial nerves and even motor/sensory nerves. What is the most common CN palsy?

A

Bell’s palsy

1052
Q

Patient that is a worker in the meat-packing industry, a veterinarian, a farmer or a traveler who consumes dairy (cow or goat) products in Mexico ore elsewhere. Possible disease?

A

Tularemia

1053
Q

Causes tularemia

A

Francisella tularensis

1054
Q

Neurotoxin of Cl.botulinum inhibits the release of _____ from peripheral nerves. Toxin is not secreted, rather It is released upon the death of bacteria.

A

Acetylcholine

1055
Q

Diagnostic test of step.pyogene that indicates presence of pyrrolidonyl arrylamidase

A

PYR test

1056
Q

Most common cause of bloody diarrhea in 1-4yrs old

A

Shigella dysenteriae

1057
Q

It is seen in secondary syphilis. In paroxysmal cold hemoglobinuria, an antibody associated with syphilis and viral infections.

A

Donath-Landsteiner antibody

1058
Q

Most common cause if UTI in sexually active women (second to e.coli)

A

Staph saprophyticus

1059
Q

Enzymes of serratia mercescens

A

Gelatinase
DNAse
Lipase

1060
Q

Most common type of salmonella infection

A

Inflammatory diarrhea

1061
Q

Erysipelas - fiery red swelling of face

A

Strep pyogenes

1062
Q

3rd most common cause of meningitis in children

A

Listeria monocytogenes

1063
Q

Cause of dental carries

A

Strep viridans

1064
Q

Culture of h.influenzae

A

Chocolate agar

1065
Q

Diseases caused by brucella

A
BUM
Brucellosis (causes undulant fever) 
Bang's disease
Undulant fever
Mediterranean fever
1066
Q

Family vibrionaceae

A

Vibrio cholera
Vibrio panhaemolyticus
Campylobacter jejuni
Helicobacter pylori

1067
Q

Trench fever

A

Bartonella quintana

1068
Q

Recurrent form of epidemic typhus

A

Brill-zinser disease

1069
Q

Can live in 6.5% NaCl and 40% bile

A

Group D strep

1070
Q

Rapidly spreading, diffuse process
Associated with lymphangitis and fever
Milroy’s disease

A

Strep cellulitis

1071
Q

Most common cause of diarrhea

A

Yersinia enterocolitica

1072
Q

Between chlamydia and rickettsia, which requires an arthropod vector?

A

Rickettsia

1073
Q

Weil’s disease

A

Leptospira interrogans

1074
Q

Infected lymph node in bubonic plague

A

Inguinal nodes (boubon is Greek for groin)

1075
Q

Caused the Black Death or the bubonic plague

A

Yersinia pestis

1076
Q

Diagnostic test for cholera

A

String test

Thiosulfate-citrate-bile salts (TCBS) agar

1077
Q

Cross reacts with rickettsiae species

A

Proteus mirabilis

1078
Q

Stain that demonstrates the metachromatic granules of corynebacterium diptheriae

A

Methylene blue

1079
Q

Female genital tract abscess

Pancreatitis

A

Bacteroides fragilis

1080
Q

Diseases caused by strep agalactiae

A

Neonatal meningitis, pneumonia and sepsis

1081
Q

Staph that causes continuous ambulatory peritoneal dialysis (CAPD)

A

Coagulase negative staph

1082
Q

Caseous necrosis is due to

A

Phosphatides

1083
Q

Epidemic typhus

A

Rickettsia prowazeki

1084
Q

Vector of rickettsia rickettsii

A

Dermacentor spp.

1085
Q

Culture for mycobacteria

A

Lowenstein-Jensen medium

1086
Q

Causes severe croup, acute supraglottic laryngitis and meningitis (3mos -3yrs)

A

H.influenza

1087
Q

T or F: mycobacterium leprae grows better in cooler temperature closer to the skin surface.

A

True. Leprosy involves the cooler are of the body.

1088
Q

H.influenzae requires two factors for growth (both found in blood)

A

Factor V - NAD

Factor X - Hemin

1089
Q

Fevers caused by leptospira interrogans

A
FCPCN
Fort Bragg fever
Canefield fever
Pretibial fever
Canicola fever
Nanukayami fever
1090
Q

Incubation period of mycobacterium tuberculosis

A

3-8 wks

1091
Q

Early congenital syphilis occurs within 2 years and is like severe secondary syphilis. What are the manifestations?

A

Condylomata latum

Snuffles : runny nose

1092
Q

Rat catcher’s yellow

A

Leptospira interrogans

1093
Q

Most common cause of meningitis in adults

A

Strep pneumoniae

1094
Q

Drug induced
Adults
Stratum germinativum

A

Toxic epidermal necrolysis (TEN)

1095
Q

Bacitracin-sensitive

A

Strep.pyogene

1096
Q

Curved gram-negative rod with a single polar flagellum

A

Vibrio cholerae

1097
Q

Produces bull’s eye target colonies

A

Yersinia enterocolitica

1098
Q

Indole positive
Beta hemolytic
Ferments lactose

A

E.coli

1099
Q

Major virulence factor of strep pyogenes

A

M protein

1100
Q
Nongonoccocal urethritis (20-30%)
Prostitis and epididimytis in men
A

Ureaplasma urealyticum

1101
Q

Hansen’s disease

A

Leprosy by mycobacterium leprae

1102
Q

Cellulitis on bone renderers and fish mongers

A

Erysipelothrix rhusfopathiae

1103
Q

Primary bacterial peritonitis

honeymoon cystitis

A

E.coli

1104
Q

Staghorn calculi

A

Proteus mirabilis

1105
Q

Wasserman reaction

A

Treponema pallidum

1106
Q

Q fever

A

Coxiella burnetti

1107
Q

Disease caused by group D strep

A

Subacute bacterial endocarditis
Biliary tract infection
Urinary tract infection

1108
Q

Lancet shape

A

Strep pneumoniae

1109
Q

Classic test that uses cross reacting OX strains of proteus vulgaris antigens to help confirm diagnosis of a rickettsial infection

A

Weil-Felix reaction

1110
Q

Mobiluncus

A

Gardnerella vaginalis

1111
Q

Dental plaques

Produce sulfur granules

A

Arachnia propionica

1112
Q

Severest form of leprosy where patients cannot mount CMI response to M.leprae.

A

Lepromatous leprosy

1113
Q

Group d strep has this thing that helps them bind to heart valves

A

Dextran

1114
Q

Rule of six in syphilis

A

Sixual transmission
6 axial filaments
6 wks incubation
6 wks for ulcer to heal
6 wks after ulcer heals,vsecondary syphilis develops
6 wks for secondary syphilis to resolve
66% of latent stage patients have resolution
6 years (at least) to develop tertiary syphilis

1115
Q

Human granulocytotrophic ehrlichiosis

A

Anaplasma phagocytophila

1116
Q

Stage of syphilis: chancre

A

Primary syphilis

1117
Q

Diseases caused by chlamydia trachomatis

A

TPL
Trachoma - corneal scarring (scar traction pulls and folds the eyelids inward so that the eyelashes rub against the conjunctiva and cornea
Pebbly conjunctiva
Lymphogranuloma venereum

1118
Q

Virulence factor of yersinia pestis

A

V and W antigen

1119
Q

Bacteroides fragilis infection occurs when the organism enters into the ..

A

Peritoneal cavity

1120
Q

Leonine facies if a manifestation of …

A

Lepromatous leprosy

1121
Q

Group D strep, alpha,beta,gamma-hemolytic

A

Enterococci (strep faecalis and faecium)

Non-enterococci ( strep bovis and equinus)

1122
Q

Motility of L.monocytogenes

A

Tumbling motility

Actin-jet motility

1123
Q

Comparison of rash from Rocky Mountain spotted fever and epidemic typhus

A

In contrast to Rocky Mountain spotted fever, epidemic typhus rash spares the palms, soles and face.

1124
Q

Enteric bacteria

A
PEKSS
Proteus mirabilis
E.coli
Klebsiella pneumoniae
Shigella dysenteriae
Salmonella typhi
1125
Q

Syphilitic reagin

A

IgG and igM

1126
Q

Has characteristic gull wing appearance at 42 degrees in culture

A

Campylobacter jejuni

1127
Q

Crepitus positive
Gas gangrene
Food poisoning (no fever)

A

Clostridium perfringens

1128
Q

Produces golden yellow colonies

A

Staph aureus

1129
Q

No lancefield classification

Alpha-hemolytic, encapsulated

A

Strep pneumoniae

1130
Q

Culture for corynebacterium diptheriae

A

TELL UR InTErn not to LOEF around

  1. Potassium tellurite agar
  2. Loeffler’s medium
1131
Q

Late congenital syphilis is similarly to tertiary syphilis except that cardiovascular involvement rarely occurs. What are the manifestations?

A

8th nerve deafness (vestibulocochlear nerve)
Saber shin (tibia leads to bowing)
Mulberry or Moon’s molar (molars have too many cusps)
Hutchinson’s teeth (incisors are widely spaced with a central notch)
Clutton’s joint (symmetrical arthrosis)

1132
Q

Some rickettsia share antigenic characteristics with …

A

Proteus vulgaris

1133
Q

Splenic abscess

A

Steptoccocal species

1134
Q

Microaerophilic bacteria

A

Helicobacter and campylobacter

Spirochetes

1135
Q

Most common cause of post-influenzal secondary bacterial pneumonia

A

Staph aureus

1136
Q

E.coli strain that causes Hemorrhagic uremic syndrome.

A

E.coli O157

1137
Q

Japanese river typhus

A

Rickettsia tsutsugamushi

1138
Q

Nonmotile enteric

A

Klebsiella pneumoniae and shigella dysenteriae

1139
Q

Rat bite fever

A

By streptobacillus moniliformis

1140
Q

Syphilis: endarteritis obliterans (inflam of inner lining of artery)

A

Syphilitic aortitis

1141
Q

Produces cherry red colonies

A

Serratia mercescens

1142
Q

Diagnostic test for Mycoplasma pneumoniae

A

Cold agglutinins

1143
Q

Puppy feces
Pica in children
Mimics appendicitis

A

Yersinia enterocolitica

1144
Q

Tiniest free living organism capable of self-replication

A

Mycoplasma

1145
Q

Strep pneumoniae produces this enzyme for mucosal colonization

A

IgA protease

1146
Q

Toxin of Cl.tetani which inhibits release inhibitory neurotransmitters (GABA, glycine) resulting in distant muscle contraction (tetany)

A

Tetanospasmin

1147
Q

Scrub typhus

A

Rickettsia tsutsugamushi

1148
Q

Greenish discharge with fishy odor

A

Gardnerella vaginalis

1149
Q

Urease positive
Phenylalanine deaminase positive
Indole negative
Does not ferment lactose

A

Proteus mirabilis

1150
Q

Purpura fulminans

A

N.menigitidis

1151
Q

Most patient with syphilis will develop an acute worsening of their symptoms immediately aft antibiotics. What is this phenomenon?

A

Jarisch-Herxheimer phenomenon

1152
Q

Has characteristic rose spots on belly

And a tongue brown and furred

A

Typhoid fever /enteric fever (Salmonella typhi)

1153
Q

Painless genital ulcer - chancroid

A

Syphilis (treponema pallidum)

1154
Q

How many organisms of v.cholerae are required to be infected?

A

100-1000 organisms

1155
Q

Obligate anaerobes

A

Clostridium

Bacteroides

1156
Q

Toxin produced by v.cholerae

A

Choleragen

1157
Q

Organisms that cause echthyma gangrenosum

A

P. aeruginosa

A. Hydrophila

1158
Q

Diarrhea caused by yersinia enterocolitica severe abdominal pain right lower quadrant, thus it often mimics what disease?

A

Appendicitis (mesenteric adenitis)

1159
Q

Reservoir of francisella tularensis and how humans get infected

A

Rabbits. From bite of ticks and deerflies

1160
Q

Bacitracin-resistant

A

Strep agalactiae

1161
Q

Stage of syphilis: tabes dorsalis (spinal cord posterior column and dorsal root)

A

Tertiary syphilis

1162
Q

This organism us ubiquitous in natural and man-made water environments. Aerosolized contaminates water is inhaled, resulting in infection. Sources such as air conditioning units and cooling towers.

A

Legionella pneumophila

1163
Q

Purpura fulminans + asplenia

A

N.menigitidis. + H.influenzae

1164
Q

Painful genital ulcer -chancroid

A

H. Ducreyri

1165
Q

Scarlitiniform rash

A

Arcanobacterium hemolyticum

1166
Q

At risk patients of salmonella typhi

A

Patients who are asplenia or have nonfunctioning spleen (sickle cell anemia)

1167
Q

Optochin-resistant

A

Strep viridans

1168
Q

Pemphigus neonatorum

A

Leptospira interrogans

1169
Q

Used to diagnose scarlet fever

A

Dick test

1170
Q

Diagnostic test for mycobacterium tuberculosis

A

Montoux test

1171
Q

Catalase and coagulase positive

Facultative anaerobe

A

Staph aureus

1172
Q

Currant jelly sputum

A

Klebsiella pneumoniae

1173
Q

Toxin that e.coli has that inhibits protein synthesis by inactivating 60s ribosomal unit

A

Verotoxin

1174
Q

Causes brain micro abscess, pyomyositis, hematogenous and contiguous focus osteomyelitis, post op infections, Ritter’s disease, localized bullous impetigo, necrotizing and nodular pneumonia

A

Staph aureus

1175
Q

Honey colored crusting

A

Staph aureus

1176
Q

Stage of syphilis: condylomata latum

A

Secondary syphilis

1177
Q

“Bull neck”

A

Corynebacterium diptheriae

1178
Q

3 most common causes of diarrhea in the world

A

Campylobacter jejuni
ETEC
Rotavirus

1179
Q

Opthalmia neonatorum
Fitz-Hugh-Curtis syndrome
PROM

A

N. gonorrheae

1180
Q

Proteus mirabilis cross reacts with _____ species

A

Rickettsiae species

1181
Q

Yersinia enterocolitica is closely related to yersinia pestis that causes bubonic plague. Their difference is in the mode of transmission.

A

Yersinia pestis: bite of a flea

Yersinia enterocolitis: fecal-oral route

1182
Q

Walking pneumoniae

A

Chlamydia pneumoniae or mycoplasma pneumoniae

1183
Q

Cat bite fever

A

Pasteurella multocida

1184
Q

Subungual hemorrhage

In s.aureus endocarditis

A

Osler’s node

1185
Q

Torulosis

Aseptic meningitis

A

Cryptococcus neoformans

1186
Q

Superficial fungal infection

A

Pityriasis versicolor

Tinea nigra

1187
Q

Fungal infection of the body

A

Tinea corporis

1188
Q

Unicellular growth form of fungi

A

Yeast

1189
Q

Coccidiodes immitis causes what diseases

A

San Joaquin fever

Desert rheumatism

1190
Q

Pilot’s wheel

A

Paracoccidiodes brasilensis

1191
Q

Can be found in pigeon droppings

A

Cryptococcus neoformans

1192
Q

Cigar-shape yeast

A

Sporothrix schenckii

1193
Q

Essential sterol in fungi

A

Ergosterol

1194
Q

Fungal infection of the groin and scrotum

A

Tinea cruris

1195
Q

T or F: spores can be transmitted from person to person

A

False. Never, it can be acquired thru inhalation as a spore.

1196
Q

Most common cns fungal infection

A

Cryptococcus neoformans

1197
Q

Subcutaneous-fungal infections gain entrance to the body following…

A

Trauma to the skin

1198
Q

Cottage cheese vaginal discharge

A

Candida albicans

1199
Q

The key to diagnosis of this fungus is doing a lumbar puncture and analyzing the CSF. An India ink test is positive.

A

Cryptococcus neoformans

1200
Q

Fungi that can grow as either a yeast or mold, depending on environmental conditions and temperature (usually growing as a yeast at body temperatures).

A

Dimorphic fungi

1201
Q

Coccidiodes immitis can be stained by

A

India ink

1202
Q

Diseases caused by Candida albicans

A

Diaper rush
Oral thrush
Vaginitis

1203
Q

Fungal infection (previously protozoa) common in AIDS

A

Pneumocystis jiroveci

1204
Q

Microorg that causes sporotrichosis

A

Sporothrix schenckii

1205
Q

Encapsulated yeasts

A

Cryptococcus neoformans

1206
Q

Madura foot

A

Pseudallescheria boydii

1207
Q

Cryptococcus neoformans is found in nature, especially in.

A

Pigeon droppings

1208
Q

Antifungal drug that inhibits ergosterol synthesis

A

Ketoconazole

1209
Q

Culture for fungi

A

Saborauds agar

1210
Q

Broad-based budding yeast

A

Blastomyces

1211
Q

Black nasal discharge + sinusitis

A

Mucormycosis / rhizopus

1212
Q

Fungal infection of the hair (scalp)

A

Tinea capitis

1213
Q

Systemic fungal infection.

A

Blastomycosis

Coccidiodomycosis

1214
Q

Infection from plant part trauma

A

Sporothrix schenckii

1215
Q

Category of cutaneous fungal infection where fungi live in the dead, horny layer of skin, hair and nails.

A

Dermathophytic cells

1216
Q

Primary manifestation of superficial fungal infections

A

Pigment change of the skin

1217
Q

Stain for pneumocystis jiroveci

A

Silver stain

1218
Q

When examined under microscope, the pus draining from the abscess of actinomyces infection reveals yellow granules called..

A

Sulfur granules

1219
Q

Subcutaneous fungal infection

A

Sporotrichosis

Chromoblastomycosis

1220
Q

Produces pseudohyphae

A

Candida albicans

1221
Q

Treatment for pneumocystis jiroveci

A

Trimethoprim-sulfamethoxazole

1222
Q

Non budding spherioles

A

Coccidiodes immitis

1223
Q

Fungus ball in the brain abscess

A

Aspergillus fumigatus

1224
Q

Eucaryotic cells that lack chlorophyll so they cannot generate thru photosynthesis. They do require aerobic environment.

A

Fungi

1225
Q

First line drugs for treatment of dermatophytoses

A

Topical imidazole

1226
Q

Reproducing bodies of molds.

A

Spore

1227
Q

Arthroconidia

A

Coccidiodes immitis

1228
Q

Fungus that has no ergosterol

A

Pneumocystis jiroveci

1229
Q

The fungi-like bacteria

A

Actinomyces

Nocardia

1230
Q

Broad hyphae invading blood vessels walls

A

Mucormycosis / rhizopus

1231
Q

Pityriasis versicolor is caused by..

A

Malassezia furfur

1232
Q

Multicellular colonies composed of clumps of intertwined branching hyphae

A

Molds

1233
Q

Fungi that live in and utilize organic matter (soil, rotten vegetation) as an energy source.

A

Saprophytes

1234
Q

Antifungal drug that destroys cm (ergosterol)

A

Amphiteracin B and nystatin

1235
Q

Causes oral thrush

A

Candida albicans

1236
Q

Rarest systemic fungal infection

A

Blastomyces

1237
Q

Fungal infection of the foot

A

Tinea pedis

1238
Q

Most common in chronic sinusitis

A

Aspergillus fumigatus

1239
Q

Fungal infection of the nails

A

Tinea unguium (onchomycosis)

1240
Q

Treatment for tinea capitis and tinea unguium

A

Oral griseofulvin

1241
Q

Rose gardener’s disease

A

Sporotrichosis. (Sporothrix schenckii)

1242
Q

Treatment for actinomyces and nocardia

A

SNAP
Sulfamethoxazole for Nocardia
Actinomyces is Pen G

1243
Q

Causes desert rheumatism and San Joaquin fever

A

Coccidioides immitis

1244
Q

Fungi can look like spaghetti (hyphae) and meat balls (spherical yeast)

A

Malassezia furfur

1245
Q

T or F: Cryptococcus neoformans is associated with AIDS.

A

True

1246
Q

Dichotomous branching hyphae

A

Aspergillus fumigatus

1247
Q

Lumpy jaw

A

Actinomyces Israeli

1248
Q

Dermatophytic cells secreted an enzyme called…

A

Keratinase

1249
Q

Treatment for Cryptococcus neoformans

A

Amphotericin B

Fluconazole (or flucytosine)

1250
Q

Lipophylic yeast

A

Malassezia furfur