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Flashcards in A&P immune system Deck (24)
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1

Define erythorcytes

RBC 5x10^6/ul

2

Define Platelets

Fragments from megakaryocytes - 150-400 thousand/uL

3

Leukocytes definie

nucleated cells of blood, WBC - in buff coat

4

Mononuclear cells

Luekocytes who nucleus has smooth outline - monocyte + lymphocytes

5

Polymorphonuclear cells

Nucleus is lobulated - aka granulocytes - prominent cytoplasmic granules - Eosinophils, basophils (mast cells) and neutrophils

6

WBC count

4,500-10,500/uL

7

Neutrophil %

40-60%

8

Eosinophils

1-4%

9

Basophils

0.5-1%

10

Monocytes

2-8%

11

Lymphocytes

20-40%

12

Central lymphoid organs

Bone marrow, Thymus

13

Peripheral lymphoid organs

Lymph nodes, spleen, peyer's patches, mesenteric lymph nodes of gut, tonsils, adenoids

14

Lymphocyte in blood --> ____ _____ ____ --> peripheral lymphoid tissue (lymph node) --> Lymph drains from node to node --> _____ _____ --> venous blood

post capillary venules
Thoracic duct

15

Antigen is defined as ____?

a substance that can be reocognized by immune system

16

Immunogen

an antigen that forms immune response

17

Tolergen

an antigen that has no immune response - prevents immune response to sequent adminstrated immunogen with same antigenic determinents

18

Epitope

part of antigen that fits into receptor (antigen determinant region)

19

Lymphocyte activation steps

Antigen fits into receptor --> several more receptors bind
Receptor binds --> cell activated when multiple receptor simultaneously bind antigen + cell surface molec
Proliferation --> divide
Differentation
T lymphocyte - T lymphoblast
B lymphocyte - B lymphoblast - plasma cell

20

Humoral immunity

antibody mediated

21

Cell mediated immuity

DC cell - no need for antibody - has receptor for "non-self"

22

Payer's patch

lymph node near entrance in small intestins

23

DC arrive at lymph in ___

Afferent lymph - gather at interface between cortex (B cell/ and paracrotx (T)

24

Order from high to low concentration of WBC normally

N>L>M>E>B