AACE Clinical Guidelines Flashcards Preview

PHM 602- Diabetes > AACE Clinical Guidelines > Flashcards

Flashcards in AACE Clinical Guidelines Deck (19)
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1
Q

Is AACE used for loose or strict targets?

A

Strict

2
Q

AACE A1C goal

A

6.5%

3
Q

AACE FBG goal

A

<110 mg/dl

4
Q

AACE PPG goal

A

<140 mg/dl

5
Q

When do you use the AACE guidelines?

A

Patients <65 without a clinical ASCVD event

6
Q

In the AACE guidelines, if a patient has established high-risk ASCVD and/or CKD, what therapies do you recommend?

A

SGLT2i and/or a long-acting GLP-1RA

7
Q

Treatment for entry-level A1C of <7.5%

A

MONOTHERAPY!

Metformin
GLP-1RA
SGLT2i
DPP4i
TZD
AGi
SU/GLN
8
Q

Treatment for entry-level A1C of ≥7.5-9.0%

A

DUAL OR TRIPLE THERAPY!

9
Q

Drugs in dual therapy

A

Metformin and one of these:

GLP-1RA
SGLT2i
DPP4i
TZD
SU/GLN
Basal insulin
Colesevelam
Bromocriptine QR
AGi

(Patients starting out on monotherapy can move here after 3 months if not at goal)

10
Q

Drugs in triple therapy

A

Metformin and two of these:

GLP-1RA
SGLT2i
TZD
SU/GLN
Basal insulin
DPP4i
Colesevelam
Bromocriptine QR
AGi

(Patients on dual therapy can move here in 3 months if not at goal)

11
Q

Entry-level A1C of 9.0% with no symptoms

A

Start dual or triple therapy

12
Q

Entry-level A1C of 9.0% with symptoms

A

Insulin +/- other agents

Patients on triple therapy can also move here in 3 months if not at goal

13
Q

AACE guidelines on starting basal insulin when A1C is <8.0%

A

TDD is 0.1-0.2 units/kg

14
Q

AACE guidelines on starting basal insulin when A1C is >8.0%

A

TDD is 0.2-0.3 units/kg

15
Q

When do you add prandial insulin?

A

Consider adding a GLP-1RA, SGLT2i, or DPP4i first before prandial insulin

16
Q

Basal Plus 1, Plus 2, Plus 3 method

A

Begin prandial insulin before largest meal, but if that doesn’t work you can progress to injections before 2 or 3 meals

17
Q

Basal Plus 1, Plus 2, Plus 3 dosing

A

10% of basal dose

18
Q

Basal Bolus method when to administer

A

Begin before each meal

19
Q

Basal Bolus dosing

A

TDD: 0.3-0.5 U/kg, 50% basal, 50% prandial

Start 50% of TDD in 3 doses