alpha-Glucosidase Inhibitors (AGI) DI Flashcards Preview

PHM 602- Diabetes > alpha-Glucosidase Inhibitors (AGI) DI > Flashcards

Flashcards in alpha-Glucosidase Inhibitors (AGI) DI Deck (14)
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1
Q

AGI MoA

A

Decreases breakdown of sucrose and complex carbs in the brush border of the small intestine

2
Q

AGI drugs

A

Acarbose (Precose), miglitol (Glyset)

3
Q

Brand name for acarbose

A

Precose

4
Q

Brand name for miglitol

A

Glyset

5
Q

Acarbose dosing

A

25mg PO TID, MDD 50mg PO TID

6
Q

Miglitol dosing

A

25mg PO TID, MDD 100mg PO TID

7
Q

AGI side effects

A

GI disturbances, weight gain

8
Q

AGI CI

A

Any GI complications

9
Q

AGI counseling

A

start low and go slow to avoid GI side effects, take with first bite of each meal- skip meal, skip dose! Ask about GI upset

10
Q

AGI pearls

A

High A1C lowering but only for patients whose diets mostly consist of complex carbs, neutral effect on ASCVD, CKD, HF

11
Q

AGI monitoring

A

PPG, A1C, GI side effects

12
Q

AGI peak effect

A

4-6 weeks

13
Q

AGI in ADA guidelines

A

They’re not mentioned anywhere

14
Q

AGI in AACE guidelines

A

Last-line option