Metformin DI Flashcards Preview

PHM 602- Diabetes > Metformin DI > Flashcards

Flashcards in Metformin DI Deck (12)
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1
Q

Metformin primary MoA

A

Decrease glucose output from liver

2
Q

Metformin secondary MoA

A

Increase peripheral muscle glucose sensitivity

3
Q

Metformin brand names

A

Glucophage, Fortamet

4
Q

Metformin dosing

A

Ideal dose is 2,000mg PO QD, but adjust to 1,000mg PO QD if eGFR 30-45 mL/min

5
Q

Metformin side effects

A

N/V, lactic acidosis (rare), abdominal discomfort, diarrhea, weight loss

6
Q

Metformin DI

A

Contrast dye- hold 24 hrs before procedure and for another 48 hrs after that

7
Q

Metformin counseling

A

Start low and go slow, take with food to avoid GI upset, avoid alcohol, stop in sick day management

8
Q

What should you ask about at metformin refills?

A

Lactic acidosis, weight loss, GI upset

9
Q

Metformin pearls

A

High A1C lowering, potential benefit in ASCVD, but neutral effects on HF and CKD

10
Q

Metformin monitoring

A

A1C, FBG/PPG, eGFR, B12 levels, weight loss, LA

11
Q

Peak effect of metformin

A

6-8 weeks

12
Q

Metformin in ADA and AACE guidelines

A

1st line in both!